Gene Information

Name : guaA (SYN_01626)
Accession : YP_463100.1
Strain : Syntrophus aciditrophicus SB
Genome accession: NC_007759
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3068649 - 3070181 bp
Length : 1533 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGATTCTTATTATTGATTTCGGTTCTCAATACAACCAGCTGATCGCCCGGCGCGTGCGGGAGCTGGAGGTGTACTGCCA
GATTGAACCCCCGGAAATTGCGCTGGAAACGATCAAGGCTCTGCAGCCGGAAGGGATTATTCTCTCCGGAGGTCCGGCGA
GCATCTACGAACCCAAAAGTCCGAAGGTGGACAAGGGGATTTTCGACTTGAACATCCCGATCCTGGGCATCTGTTACGGC
CTGCAGTACATGGTTGACTCCCTGGGTGGCAAAGTGATCCGGTCGGCAAAGCGGGAATACGGGTTTGCCCAGCTCCACAT
TGTTCGGGAGGGAAAGGGAATCTTTGCGGGGGTAACGGAAAACACCCGCTGCTGGATGAGTCATGGCGATACGATCGACC
AGTTGCCCGCAGGCTTCGCGATCACGGCCTCTACGGCCAATACCCCCGCCGCGGCGATGGAAGATCCGGTTCGGCGGCTT
TACGGCCTGCAGTTCCACCCCGAAGTGGTTCATACGCCGGAAGGGAAAAAGATGCTGGAAAATTTCCTCTTTTCCGTCTG
CGGCTGCCGGAAGAGCTGGACCATGGCGTCCTTCATCCGGGATTCCGTGGAAGAGATCCGGTCAACCGTTGGAGACCGGA
AGGTCGTCCTTGGTCTGAGCGGCGGCGTGGATTCTTCCGTGGCGGCGCTGCTTCTTCATCAGGCCATCGGCAATCAGTTG
ACCTGTGTTTTTGTCGATAACGGCCTCCTGCGGCAGGGAGAGGCGGAAAAGGTCCGATCGCTCTTCAAACAGCATTTTCA
CATGAATGTCCGCTTCGCCCGGGCCAAGGCCCAGTTTCTCGATGCCCTGAAAGGCATCGTGGATCCTGAACGGAAGCGCA
AGATCATTGGCCGAGTCTTTGTCGAAGTCTTTGATCAGGAAGCGCGAAAAATCCGGGATGTGGATTATCTGGCACAGGGG
ACCCTCTATCCCGACGTGATCGAATCCCGTTCCGCCTTCGGCGGTCCAAGTGCGGTGATCAAGTCCCACCATAACGTGGG
CGGACTCCCCCGGCGGATGAAACTGAAGCTGATCGAGCCGCTGAAACACCTTTTCAAGGATGAGGTGCGCCTCCTCGGCA
GGGAGCTGGGACTCTCCGACGACATGATCTGGCGGCACCCCTTCCCCGGCCCCGGTCTGGGCATCCGGATCATCGGCGAG
GTGACGGACAAACGGCTGTCCCTCCTCCGCAAGGCCGATGCCATCCTGCTGGAGGAGATCAAGGCCGCCGATTACTATGG
CCGGCTCTGGCAGTCATTCGTCGTCCTGCTTCCCCTGAAAAGCGTCGGGATTATGGGCGATCAGCGAACCTATGAACATA
TCGCGGCCATCCGGGCCGTCACCAGCGATGACGCCATGACGGCGGACTGGGCGCGGCTTCCTCATGATCTGCTGGGAAAG
ATTGCCAATCGGATCATCAACGAGGTCCGGGGAATCAATCGCGTGGTCTACGATATCAGCTCCAAACCACCCAGCACGAT
TGAATGGGAATAA

Protein sequence :
MILIIDFGSQYNQLIARRVRELEVYCQIEPPEIALETIKALQPEGIILSGGPASIYEPKSPKVDKGIFDLNIPILGICYG
LQYMVDSLGGKVIRSAKREYGFAQLHIVREGKGIFAGVTENTRCWMSHGDTIDQLPAGFAITASTANTPAAAMEDPVRRL
YGLQFHPEVVHTPEGKKMLENFLFSVCGCRKSWTMASFIRDSVEEIRSTVGDRKVVLGLSGGVDSSVAALLLHQAIGNQL
TCVFVDNGLLRQGEAEKVRSLFKQHFHMNVRFARAKAQFLDALKGIVDPERKRKIIGRVFVEVFDQEARKIRDVDYLAQG
TLYPDVIESRSAFGGPSAVIKSHHNVGGLPRRMKLKLIEPLKHLFKDEVRLLGRELGLSDDMIWRHPFPGPGLGIRIIGE
VTDKRLSLLRKADAILLEEIKAADYYGRLWQSFVVLLPLKSVGIMGDQRTYEHIAAIRAVTSDDAMTADWARLPHDLLGK
IANRIINEVRGINRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-142 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-142 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-142 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-124 49