Gene Information

Name : leuS (SYN_02374)
Accession : YP_460226.1
Strain : Syntrophus aciditrophicus SB
Genome accession: NC_007759
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 188856 - 191444 bp
Length : 2589 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAACAGAAAATATGTGCCTCAGGAAATTGAAGAGAAGTGGCAGCGATACTGGGAAGAAAAAAATACTTTCAAGGTGAC
GGAAGATCCTTCAAAGAAAAAATACTATCTTCTGGAAATGTTTCCTTATCCCTCCGGCAAGATTCATATCGGCCACGTGA
GAAACTATACAATCGGCGATGTCGTTGCCCGCTACAAGCGAATGGAAGGGTACAACGTCCTGCACCCCATGGGTTGGGAC
TCCTTCGGCATGCCGGCGGAAAATGCGGCCATTGAACGGGGCATCCACCCTTCTCTCTGGACGAATGAAAATATCACTCA
CATGAGAAAGCAGCTCAAGCGAATGGGCTTCAGCTACGACTGGGACCGCGAGGTCTCGACCTGCGAACCGGTATACTACC
GCTGGGAACAGCTTTTCTTCCTCTGGATGTACGAAAAAGGGCTAGCCTACAAAAAGACTTCCAGCGTGAACTGGTGTCCC
AGGTGTCAGACCGTTCTGGCCAACGAGCAGGTGGAAGCCGGACTATGCTGGCGATGCGGTTCCGAAGTGGTGGAAAAAAT
CCTCGATCAGTGGTTTTTCCGCATCACCGCCTACATCGATGAACTCCTGGCGGGGTGCGACCGGTTGACGGGATGGCCGG
AGCGGGTGCTGACCATGCAGCGGAACTGGATCGGCAAGAGTTACGGCTGTGAGGTCTCGTTCCCCATGGCGGACGGCAAC
GGCGACATCAAGGTGTTTACCACCCGTCAGGATACCCTGTTCGGTGCAACCTTCATGCTGATTGCCGCCGAACATCCCCT
GGTCATGGAACTGATCAAGGGGAAACCTGTTGAAAAGGATGCCAGGACCTTCGCCGAAGAAGTCAAGAAACAGGACAAGC
TCATGCGGACATCGGATTATTATGAAAAGCAGGGGCTGTTCCTCGACTGTTACTGCCTCAATCCACTGACCGGCTGGGAG
ATGCCGATCTTTGCGACCAATTTTGTTCTCGCGGATTACGGCACCGGCTGCGTGATGGCCGTTCCGACTCATGACCAGCG
GGACTTCGAATTTGCCGAAAAATTCGGTCTCCGCAAGGTGGTGGTCATTTCGCCGCCGGACAAGACCCTTGATCCGGAAA
CCATGACGGAGGCCTATGTGGAGGAAGGCATCCTGGTCAATTCCGGACCCTTTAATGGAATGGAAAATCTCAAAGCCCTG
GACGCGATCGCCGATCATCTGATCGCCCTGGGACGGGGCAAACGAACGATACAATACCGGCTGCGGGACTGGGGCATCTC
CCGGCAGCGTTACTGGGGAGCGCCGATCCCCATGATCATGTGTCCTAAATGCGGTACGGTGCCGGTTCCGGAGGCCGAGC
TTCCCGTTGTGCTGCCTCGGGATGTCGATTTTTCGGGAGAAGGCGGATCACCCCTCGCGAAACACCCCGAATTTCTGAAC
ACGACCTGCCCTTCTTGCGGCGGCCCCGCGAAGCGGGAAAGCGATACGATGGACACCTTTGTGGAATCCTCCTGGTATTT
CGAACGTTACTGCTGCCCCCATTTCGCAGAAAAGCCCGGCCTGAACAGACAGCAGGTGGATTACTGGATGCCCGTGGATC
AGTACATCGGCGGGATCGAACATGCCATCCTTCACCTCCTCTACGCCCGCTTTTACACCAGGATGCTCCGGGACTTCGGT
CTGGTGGGGGTCGATGAACCCTTTACGAATCTGTTGACTCAGGGCATGGTCTGCAAAGAAACGACCCGCTGCCCCGATCA
CGGCTATCTCTACCCGGAAGAAGTCCGTGAAGGTCGATGCATCCACTGCCTGGCCGAAGTGATCGTCGGCAAGACGGAGA
AAATGTCCAAATCCCTAAAGAATGTGGTCGACCCCGATTATCTGGTCCGGCAGTACGGAGCGGATACAGCCCGGATGTTC
TGTCTTTTCGCCGCGCCGCCGGAGAAAGACCTGGAGTGGAGCGATCAGGGGGTGGAGGGATCGTTCCGTTTTATCGGCCG
GACCTGGCGCATTGTCGTGGATTATCTGGATGATCTTCAGGGAATTGCCCCCTTTGCGGGCGACGGGGAACTGGAAGGCG
AACTGAAGAGCCTGCGGCGCAAGACCCACCAGACAATCAGGAAGGTCCGGGATGATATGGGCGAGCGTTTCCATTTCAAT
ACGGCCATCAGCGCCATCATGGAACTGGTCAACACCCTGTACGGTCTGCCCCGACCGCCCCGGGAAGACCGGACGGCCCT
GGCCGTGATCCGGGAGACGATCGAAGCGATTATCCTGCTGCTGGCGCCGATTGTACCCCATCTCACCGAGGAACTCTGGC
AGATGCTGGGACATCAAGGAACCTGCCTGGCTGACACACCTCTGCCGGTTTATGATCCCACCGTCGCCGCTGAAGACGAA
ATGACCATCGTCATTCAGGTGAACGGCAAAGTGCGGAGCCGGGTCATCGTGGCAGCAGATGAAGCTGAAGATAAAATCAA
GGCGCTGGCGATGGGTGATGAGAAGGTATCCCGGTTCCTTGAGGGAAAATCCGTGATCAAGCAGGTCTACGTACCGAAAA
AGCTGGTGAATATTGTCGTGAAGGGTTGA

Protein sequence :
MNRKYVPQEIEEKWQRYWEEKNTFKVTEDPSKKKYYLLEMFPYPSGKIHIGHVRNYTIGDVVARYKRMEGYNVLHPMGWD
SFGMPAENAAIERGIHPSLWTNENITHMRKQLKRMGFSYDWDREVSTCEPVYYRWEQLFFLWMYEKGLAYKKTSSVNWCP
RCQTVLANEQVEAGLCWRCGSEVVEKILDQWFFRITAYIDELLAGCDRLTGWPERVLTMQRNWIGKSYGCEVSFPMADGN
GDIKVFTTRQDTLFGATFMLIAAEHPLVMELIKGKPVEKDARTFAEEVKKQDKLMRTSDYYEKQGLFLDCYCLNPLTGWE
MPIFATNFVLADYGTGCVMAVPTHDQRDFEFAEKFGLRKVVVISPPDKTLDPETMTEAYVEEGILVNSGPFNGMENLKAL
DAIADHLIALGRGKRTIQYRLRDWGISRQRYWGAPIPMIMCPKCGTVPVPEAELPVVLPRDVDFSGEGGSPLAKHPEFLN
TTCPSCGGPAKRESDTMDTFVESSWYFERYCCPHFAEKPGLNRQQVDYWMPVDQYIGGIEHAILHLLYARFYTRMLRDFG
LVGVDEPFTNLLTQGMVCKETTRCPDHGYLYPEEVREGRCIHCLAEVIVGKTEKMSKSLKNVVDPDYLVRQYGADTARMF
CLFAAPPEKDLEWSDQGVEGSFRFIGRTWRIVVDYLDDLQGIAPFAGDGELEGELKSLRRKTHQTIRKVRDDMGERFHFN
TAISAIMELVNTLYGLPRPPREDRTALAVIRETIEAIILLLAPIVPHLTEELWQMLGHQGTCLADTPLPVYDPTVAAEDE
MTIVIQVNGKVRSRVIVAADEAEDKIKALAMGDEKVSRFLEGKSVIKQVYVPKKLVNIVVKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-154 41