Gene Information

Name : spaP (SG0569)
Accession : YP_454249.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaP
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4790
EC number : -
Position : 965092 - 965772 bp
Length : 681 bp
Strand : +
Note : part of a type III secretory system probably involved in invasion into eukaryotic cells

DNA sequence :
ATGCTCACCAACGACATGACGCTCATTGTTTTACTTTCGTTCACCACCCTGTTGCCCTTTGTGATAGCGGGGGGCACCTG
CTATATCAAATTTTCTATCGTACTGGTGATGGTGCGAAATGCGCTGGGCATACAGCAAATACCTTCTACGCTTACGCTTA
ATGGTATTGCGCTGATATTAACCGCTTTCGTTATGATGCCTGTTTGCCAAAATATAAGCCACTATATCGAAACGCATCAG
ACCAATTTTAATAATATTGACTCAACGATGCAATTTGTCGACCAAGGCCTGGGAAGTTATAGAGACTATTTAGTACGTTA
TTCAGATAAAAAATTGATTCGCTTTTTTTGTGAGACCCAACATCGACAAAGCGGCGGCGAGCAGGAAACGGATCTTGAAT
GCACCGAAGAGAATATGTCATCGTTGTCATTGATGATGCTGATGCCTGCCTATGCGCTCAGTGAGGTACAAAGTGCATTT
AAAATTGCCTTCTTTTTGTATGTCCCCTTTGTCGTTATTGATATGGTGGTCTCCAGTATACTACTCGCGCTGGGGATGAT
GATGATGAGTCCAGTCACTATTTCAATACCTATCAAATTGATCCTGTTTGTGGCAATGGACGGTTGGACCTTATTAACAA
AAGGACTGATCCTGCAATATGCGGATTTGATTAAGCAATGA

Protein sequence :
MLTNDMTLIVLLSFTTLLPFVIAGGTCYIKFSIVLVMVRNALGIQQIPSTLTLNGIALILTAFVMMPVCQNISHYIETHQ
TNFNNIDSTMQFVDQGLGSYRDYLVRYSDKKLIRFFCETQHRQSGGEQETDLECTEENMSSLSLMMLMPAYALSEVQSAF
KIAFFLYVPFVVIDMVVSSILLALGMMMMSPVTISIPIKLILFVAMDGWTLLTKGLILQYADLIKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ysaR AAS66846.1 YsaR Not tested SSR-1 Protein 4e-98 100
spaP YP_217809.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 6e-60 60
spaP NP_461811.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 6e-60 60
spaP NP_457284.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 1e-59 60
spaP NP_806493.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 1e-59 60
spaP NP_311752.1 surface presentation of antigens protein SpaP Not tested LIM Protein 2e-60 57
epaP AAZ31293.1 EpaP Virulence ETT2 Protein 2e-59 56
spaP AAS66865.1 SpaP Not tested SSR-2 Protein 1e-58 52
lscR AAO18040.1 LscR Virulence TTSS locus Protein 9e-39 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG0551 Protein 2e-60 60
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG2455 Protein 1e-60 59
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG1012 Protein 2e-57 58
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG1773 Protein 5e-65 58
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG0394 Protein 2e-39 42
spaP YP_454249.1 surface presentation of antigens protein SpaP VFG0044 Protein 5e-38 41