Gene Information

Name : SG0565 (SG0565)
Accession : YP_454245.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Virulence
Product : ATP synthase SpaL
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 961568 - 962875 bp
Length : 1308 bp
Strand : +
Note : Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase

DNA sequence :
ATGAGAAGAAGTCCTCTGCAAAATTGTTTTGACTATGCGGCCCATCCAACGCGGATTCAGGGAAACATTATTGAAGCCAG
TTTGCCGGCGGCCGCGATCGGCGAAGTCTGTGAAGTGCTGTCATCAATTAACGACACTTCTCTGGCGGGTTATGCCCGGG
TCATTGGTTTCAACGGCAGTCGCACCATGCTGAGCCTGCTTTGCGATAGCGCGGGATTTTCCCAGCACCATCTTTTGGTG
CCCACCGGTAAACCTTTCCAATTCCCTCTGGGGGAGGCCTTATTGGGGGCGGTGCTTGACCCGCTGGGAAATATCTGCGC
ACGGCTGGACGGCGCAACGGAGACGGCGCTTATCGCCACCGAACATAGGCCGATTGACGTGGAGGCGCTGCATTTTAGCG
AACGTGAGCCTATCGCGGAAAAACTCATTACGCGGATCCGTGCCATTGATGGCTTATTAACCTGTGGACACGGCCAGCGG
TTGGGTATTTTCGCAGCGGCGGGCTGCGGAAAAACATCGTTAATGAATATGTTGATTGAGCACTCCGAGGCTGACGTTTA
TGTCGTGGGACTTATTGGAGAACGTGGCCGCGAAGTGACGGAATTCATCGAAGAGTTAAAACATTCCTCGCGCAGCGGGA
AAGTGGTGCTGGTGAATTCGACTTCGGATCGCTCCTCGGTGGAACGCTGTAATGCGGCGCAGGTGGCCACCACTGTCGCT
GAATATTTTCGCGACCAAGGCAAAAACGTGCTGTTGTTCATTGATTCAATCACACGTTATGCGCGCGCATTGCGCGATAT
GGCGTTAAGCATGGGGGAATTACCCGCGCGGCGCGGGTACCCCGCGTCGGTGTTTGAACGCTTACCCAAGCTGCTTGAAC
GACCGGGCAGCAGCCAGTTGGGATCCATTACCGCCTTTTATACCGTGCTGCTGGAAAATGAGGAAGAACCGGATGCAATC
GGTGATGAAGTAAGGTCGATCCTCGATGGCCATATTTATCTCAGCCACACTCTGGCAGCCCAGGGGCATTACCCGGCCAT
AGACATATTACGCAGCACCAGCCGACTGTTTCTACAAATTACCGACAAGCAACAGCAGCGTGCCGCCGTTCGTTTTCGCG
ATTTATTAGTTCGCCAGCGAGATATGCAGCTCTATCTGGACTTGGGTGAATACCGTCGTGGTGAAAATCAGGAAAACGAT
AACGCTTTCGATAAAGAAAACATCATGAGCGATTTTTTGCGCCAGCCGCTGGACGAATGTATGGAATTTAGCCAAACACT
GGAGCGATTGAATGAATGTCTGGCTTAG

Protein sequence :
MRRSPLQNCFDYAAHPTRIQGNIIEASLPAAAIGEVCEVLSSINDTSLAGYARVIGFNGSRTMLSLLCDSAGFSQHHLLV
PTGKPFQFPLGEALLGAVLDPLGNICARLDGATETALIATEHRPIDVEALHFSEREPIAEKLITRIRAIDGLLTCGHGQR
LGIFAAAGCGKTSLMNMLIEHSEADVYVVGLIGERGREVTEFIEELKHSSRSGKVVLVNSTSDRSSVERCNAAQVATTVA
EYFRDQGKNVLLFIDSITRYARALRDMALSMGELPARRGYPASVFERLPKLLERPGSSQLGSITAFYTVLLENEEEPDAI
GDEVRSILDGHIYLSHTLAAQGHYPAIDILRSTSRLFLQITDKQQQRAAVRFRDLLVRQRDMQLYLDLGEYRRGENQEND
NAFDKENIMSDFLRQPLDECMEFSQTLERLNECLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 0.0 100
invC AAS66861.1 InvC Not tested SSR-2 Protein 6e-109 57
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-111 56
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-111 56
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-111 56
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-111 56
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-105 54
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-82 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-74 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-74 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-76 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-75 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-66 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-70 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-66 44
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-68 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-78 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-78 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-67 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-67 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-76 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-76 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-76 44
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-69 44
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-69 44
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-69 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-69 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-69 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-68 44
escN AAC38383.1 EscN Virulence LEE Protein 5e-70 43
escN AAK26715.1 EscN Virulence LEE Protein 4e-68 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-70 43
escN AAC31513.1 L0034 Virulence LEE Protein 3e-70 43
escN AAL57542.1 EscN Virulence LEE Protein 4e-68 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-70 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-68 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-70 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-68 43
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-68 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-68 43
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-71 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-61 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-61 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-59 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-69 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-64 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-64 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-64 42
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-67 41
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SG0565 YP_454245.1 ATP synthase SpaL VFG2459 Protein 4e-118 59
SG0565 YP_454245.1 ATP synthase SpaL VFG0555 Protein 3e-111 56
SG0565 YP_454245.1 ATP synthase SpaL VFG1778 Protein 1e-110 56
SG0565 YP_454245.1 ATP synthase SpaL VFG1008 Protein 9e-105 51
SG0565 YP_454245.1 ATP synthase SpaL VFG0390 Protein 5e-80 48
SG0565 YP_454245.1 ATP synthase SpaL VFG0048 Protein 4e-81 46
SG0565 YP_454245.1 ATP synthase SpaL VFG0192 Protein 6e-84 45
SG0565 YP_454245.1 ATP synthase SpaL VFG2144 Protein 2e-73 45
SG0565 YP_454245.1 ATP synthase SpaL VFG1254 Protein 4e-74 44
SG0565 YP_454245.1 ATP synthase SpaL VFG0515 Protein 2e-69 44
SG0565 YP_454245.1 ATP synthase SpaL VFG0730 Protein 3e-70 43
SG0565 YP_454245.1 ATP synthase SpaL VFG0812 Protein 2e-70 43