Gene Information

Name : murD (SG0447)
Accession : YP_454127.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 781034 - 782350 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGACGGACTATCGGGGCGAACAAGTGGTCATCATCGGGCTGGGGCTTACCGGCCTTTCCTGCGTTGACTTTTTGCGCCG
CCGCGGCGTGACGCCGCGGGTGATGGACACCCGTTTTACACCGCCGGGTCTGGAGAAACTGCCGGCCGATGTGCCGCGCC
ACCTGGGGTCGTTGCATGAACAGTGGCTGCTCGACGCTACGCTTATCGTCACCAGCCCCGGCGTTCCCCTGTCGCATCCC
GCGCTGGCCGAGGCCGCGGCGGCCGGCGTTGCCATTATCGGCGATATAGAGCTCTTTGCGCGTGAGGCATCGGCGCCGGT
GGTGGCGATAACCGGCTCCAACGGCAAAAGCACCGTCACCTGTATGGTGGGCGAAATGGCCGCCGCCGCCGGCTGGCAGG
TGGGCGTTGGCGGCAATATTGGTCTGCCGGCGCTGACGCTTTTGGATTCGCCGTGCCAGCTGTATGTTCTGGAGTTGTCG
AGTTTCCAGTTGGAAACCACACATAGCCTGAAAGCGGCGGCGGCGACGGTTCTTAATATCAGTGAAGACCACATGAACCG
CTATCCGCTTGGCCTGCAACAGTACCGGGCAGCCAAGCTGAAAATTTACCACGATGCCGCGGTCTGCGTGGTCAACGCAG
AGGATGCGCTCACCCTGCCGGTGCGCGGACATGACGCGCGCTGCATCAGCTTCGGCGCGGAGCGCGGCGACTACTGCCTC
CGCCGGCATGCGGGGCAGACCTGGCTGATGGCGCGCGGTGAGCCGCTGCTGGAAGGCGCGGAACTGCGCGTTGGCGGCCG
CCATAATTACACCAACGCCCTGGCGGCGCTGGCGCTGTCGGATGCGCTGGGCATTCCGAGCGCTGCAAGTCTGGCGGCGC
TGCGTCAGTTCCGCGGTCTGACGCACCGTTTTGAATTAGTGCATGAACGCCGCGGCGTACGCTGGATTAATGATTCCAAA
GCGACCAATGTGGGCAGTACCGAGGCGGCGCTGAACGGACTGGAGGTGGTGGGTACGCTCCATTTACTATTGGGCGGCGA
TGGTAAATCCGCCGATTTCACGCCGCTGACGCCGTGGCTGCAGGGAGACCGGGTACAGCTGTATTGTTTCGGCCAGGATG
GCGCGCAGTTGGCGTCCCTGTGTCCTGAAGCCGCTACGCTCACCGAGACGCTTGAGCAGGCGATGCGCATCATCGGTTCC
CGGGTGAGGGCAGGGGATCTGGTGCTGCTGTCGCCGGCCTCCGCCAGCCTGGATCAGTTCAGCAATTTTGAAGTGCGTGG
TGACGTATTCACCCGCCTGGCGCGGGAGGTGGGTTGA

Protein sequence :
MTDYRGEQVVIIGLGLTGLSCVDFLRRRGVTPRVMDTRFTPPGLEKLPADVPRHLGSLHEQWLLDATLIVTSPGVPLSHP
ALAEAAAAGVAIIGDIELFAREASAPVVAITGSNGKSTVTCMVGEMAAAAGWQVGVGGNIGLPALTLLDSPCQLYVLELS
SFQLETTHSLKAAAATVLNISEDHMNRYPLGLQQYRAAKLKIYHDAAVCVVNAEDALTLPVRGHDARCISFGAERGDYCL
RRHAGQTWLMARGEPLLEGAELRVGGRHNYTNALAALALSDALGIPSAASLAALRQFRGLTHRFELVHERRGVRWINDSK
ATNVGSTEAALNGLEVVGTLHLLLGGDGKSADFTPLTPWLQGDRVQLYCFGQDGAQLASLCPEAATLTETLEQAMRIIGS
RVRAGDLVLLSPASASLDQFSNFEVRGDVFTRLAREVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 9e-58 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 9e-58 43