Gene Information

Name : spaP (SG2084)
Accession : YP_455764.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaP
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4790
EC number : -
Position : 3589615 - 3590316 bp
Length : 702 bp
Strand : -
Note : part of a type III secretory system probably involved in invasion into eukaryotic cells

DNA sequence :
ATGACCGCTAATCTCGACCTGCCCAACGACATGGGACTTATCGGGATTCTGGCACTGGCAACCCTATTGCCTTTTATCAT
TGCCTCCGGCACCTGCTATATCAAATTCTCCATCGTCTTCGTTATGGTGCGCAACGCTCTGGGCCTGCAGCAGGTGCCTT
CCAACCTTACTCTGAACGGTATCGCGCTGATGCTGGCGATGTTTATCATGGGGCCTATCGCCGGCGATGCCTATAATGCC
TACCAGGAGCAGCCGGTGGCGTTGGGCAGCGCCGCCTCGGTGCTGGAATTTCTGGAAAACAGCATGGAGTCCTACCGGCA
TTATCTGCAGAAATACGCCGACCCGCGCCTGACTGAATTCTTCGATCGGGCTCACGGTGGCGGCGGTGCTGCGCATGACG
CACCCGCGTCCGGTCATGCGCCCTCCATGTTGGCGCTATTGCCTGCCTATGCGCTAAGTGAAATCAAGGACTCCTTCAGA
ATCGGCTTTTATCTGTATCTTCCCTTTGTGGTGGTGGACCTGCTGATTTCCAGCGTTTTGCTGGCGTTGGGCATGATGAT
GATGAGCCCGATTACCCTGTCGGTGCCGATAAAATTGGTGTTGTTCGTCATGCTCGACGGTTGGACGCTGCTATCGCAAG
GGCTGGTTCTGCAATATCTCGATATGGGTGCCGGCGCGGAGATTGCGGGGGGCCCGGGATGA

Protein sequence :
MTANLDLPNDMGLIGILALATLLPFIIASGTCYIKFSIVFVMVRNALGLQQVPSNLTLNGIALMLAMFIMGPIAGDAYNA
YQEQPVALGSAASVLEFLENSMESYRHYLQKYADPRLTEFFDRAHGGGGAAHDAPASGHAPSMLALLPAYALSEIKDSFR
IGFYLYLPFVVVDLLISSVLLALGMMMMSPITLSVPIKLVLFVMLDGWTLLSQGLVLQYLDMGAGAEIAGGPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaP AAS66865.1 SpaP Not tested SSR-2 Protein 9e-81 100
spaP NP_457284.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-49 60
spaP NP_806493.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 2e-49 60
spaP YP_217809.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 9e-50 60
spaP NP_461811.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 9e-50 60
spaP NP_311752.1 surface presentation of antigens protein SpaP Not tested LIM Protein 5e-52 59
epaP AAZ31293.1 EpaP Virulence ETT2 Protein 1e-50 58
ysaR AAS66846.1 YsaR Not tested SSR-1 Protein 7e-44 51
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 3e-27 41
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 9e-28 41
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 3e-27 41
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 1e-27 41
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 1e-27 41
lscR AAO18040.1 LscR Virulence TTSS locus Protein 1e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG1012 Protein 1e-49 60
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG0551 Protein 4e-50 60
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG2455 Protein 7e-49 57
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG1773 Protein 4e-46 54
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG0188 Protein 9e-34 43
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG0394 Protein 3e-30 41
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG0044 Protein 1e-28 41
spaP YP_455764.1 surface presentation of antigens protein SpaP VFG0519 Protein 5e-28 41