Gene Information

Name : SG2081 (SG2081)
Accession : YP_455761.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaS
Function : -
COG functional category : N : Cell motility
COG ID : COG1377
EC number : -
Position : 3587509 - 3588567 bp
Length : 1059 bp
Strand : -
Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins

DNA sequence :
ATGAGTAATAAAACCGAGAAGCCGACGCCTAAGCGCCTGCGCGACGCTGCTAAAAAAGGGCAAGCCTTCAAATCCCGCGA
CGTCATCATTGCCTGCATGATGTTATGCGGTGTCTGTTGGCTAACCTCCTTCACCTCGCTTGAGAGCCTGATGGATCTTT
ATCGCCAAATGGTGGTCGGCAATTTTTCGTTATCGCTGACCGCCTACCGCAATGCACTGATGTTTACCGCGCTACAAATA
CTGCTGCCCATCATAGCAATGGGCATTGTGGCATCAGCGCTGCCGTTGCTGCTGCAAACCGGCTTTATGCTGGCGACCCG
GGCCTTCAAGCTCAACTTTCAGGCGCTTAACCCCACCCGCGGTATCAAGAAAATATTCAGTCTGCGCACTGCGAAAGACT
GTGTAAAGGCGCTGCTGTATTTGGCCGCTTTCGCTATAGCGTTGATGATAGTCTGGCGCACCCATCGGCAGCTCTTGTTT
GAGCAACTGTTTGCCAATCCGCAGGACATCGTCGCCATTTGGCGGCAATTGCTTATGTCGCTGGTGCTAACCTGCCTGCT
GTGTATTGTCTGTATAGTGATATTGGATATCGTAGCTGAATATTTTCTGCACCTGCGCAGTCTCAAAATGGACAAGCAAG
AGGTTAGGAGGGAGATGAAAGAGCAGGAAGGAGACCCGGAGATTAAACATCGCCGCCGCGAGGCTCATATGGAGATCTTG
TCTGAGCAGACGCAAGCCGATATTAAAGGGTCGCAGTTGATCATTGCAAATCCTACCCATCTTGCTGTGGGCATTTATCA
TAATCCCGATTTGACCCCTTTGCCGTTTATCTCGGTGCTGGAACGCAATCAACGGGCGTTGGCCGTGCGCGACTATGCGA
AAAAGGTCGGTGTATCGGTGATTGAAGATGTTCAGCTGGCCCGTCGGATATATTATACGCATCACCTATATTCTTTTGTT
AAGATTAACGAGTTGGATCAGGTACTCCGCTTATTAAGCTGGTTGCAGGATGTGGAAAATGCCGGGCGTTATGATTATGC
AAAAGAAAGTGAGGAATAG

Protein sequence :
MSNKTEKPTPKRLRDAAKKGQAFKSRDVIIACMMLCGVCWLTSFTSLESLMDLYRQMVVGNFSLSLTAYRNALMFTALQI
LLPIIAMGIVASALPLLLQTGFMLATRAFKLNFQALNPTRGIKKIFSLRTAKDCVKALLYLAAFAIALMIVWRTHRQLLF
EQLFANPQDIVAIWRQLLMSLVLTCLLCIVCIVILDIVAEYFLHLRSLKMDKQEVRREMKEQEGDPEIKHRRREAHMEIL
SEQTQADIKGSQLIIANPTHLAVGIYHNPDLTPLPFISVLERNQRALAVRDYAKKVGVSVIEDVQLARRIYYTHHLYSFV
KINELDQVLRLLSWLQDVENAGRYDYAKESEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 2e-145 100
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 9e-78 56
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-78 56
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 8e-79 56
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 8e-79 56
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 3e-59 47
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 1e-55 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SG2081 YP_455761.1 surface presentation of antigens protein SpaS VFG0548 Protein 9e-79 56
SG2081 YP_455761.1 surface presentation of antigens protein SpaS VFG1015 Protein 2e-67 46
SG2081 YP_455761.1 surface presentation of antigens protein SpaS VFG2452 Protein 2e-48 44