Gene Information

Name : SG0998 (SG0998)
Accession : YP_454678.1
Strain : Sodalis glossinidius morsitans
Genome accession: NC_007712
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1642627 - 1643382 bp
Length : 756 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTATCGCCATTATTCCCGCTCGTTTCGCCTCCAGCCGCCTGCCCGGCAAGCCGTTGGCCGATATCAACGGCAA
ACCCATGGTGGTCCGTGTCATGGAGCGGGCGCAAGCCTCTGGCGCCGATCGGGTCATTGTCGCGACCGATCATCAAGGGG
TAGTCGAAGCGGTTGAGCGCGCCGGCGGCGAAGTGTACCTGACTCGTCCCGATCATCAGTCCGGCACCGAGCGGCTGCAG
GAGGTTATCGATCGCTACGACTTCCCTGACGATCGGATTATCGTCAATGTGCAGGGCGACGAGCCGCTCATTCCGCCGCA
AATCATCCTCCAGGTGGCGGATAACCTGGCGGGGGCAGAGGCTGGCATGGCCACACTGGCGGTGCCTATTACCACCGCAG
AAGAGGCATTCAACCCCAACGCGGTAAAAGTGGTGGTGGATGCGCGCGGTTATGCGCTGTATTTCTCCCGTGCGACTATC
CCGTGGGACCGCGAAGGATTTGCCCGCAGCCGTGAGCACCTTTCTCATAGCCTGCTGCGCCATATCGGGATTTATGCCTA
TCGCGCCGACTTTATACGTCGCTACGTCAGCTGGTCTGCCAGTCCGTTGGAGAAGATTGAGATCCTCGAACAACTGCGCG
TTCTGTGGTACGGCGAAAAAATTCATGTCGCAGTGTCGAGCGTCGCGCCCGGCATGGGCGTGGACACGCCTGAAGAGCTG
GCGCAGGTCCGTTTGCTGCAGCAACAGCTGGATTAA

Protein sequence :
MSFIAIIPARFASSRLPGKPLADINGKPMVVRVMERAQASGADRVIVATDHQGVVEAVERAGGEVYLTRPDHQSGTERLQ
EVIDRYDFPDDRIIVNVQGDEPLIPPQIILQVADNLAGAEAGMATLAVPITTAEEAFNPNAVKVVVDARGYALYFSRATI
PWDREGFARSREHLSHSLLRHIGIYAYRADFIRRYVSWSASPLEKIEILEQLRVLWYGEKIHVAVSSVAPGMGVDTPEEL
AQVRLLQQQLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-33 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-33 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-33 46