Gene Information

Name : thiC1 (Msp_0228)
Accession : YP_447288.1
Strain : Methanosphaera stadtmanae DSM 3091
Genome accession: NC_007681
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : 2.5.1.3
Position : 286378 - 287667 bp
Length : 1290 bp
Strand : +
Note : thiamine biosynthesis protein 1; required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
TTGACTCAATTAGAATATGCAAGAAAAGGAGAAATAACTCCTGAAATGGAATATGTAGCAAAAACTGAAAATATAGATGT
TGAAAAATTAAGAAAAAATATAGCTTCTGGAAAAGTAGTTATACCAAAAAATGTGCATAATAATACTCTTCCAACTGGAA
TTGGTAAAGATTTACATACAAAAATTAATGCAAATATAGGATCATCTACAGAAATGGAAGATATTAATGTAGAGCTAGAA
AAACTAGATATACTACTAAAATATGGTGCAGATGCTGTGATGGATTTAAGTACTGGACCAAAATTACATGAAATCAGAAA
GGCAATAAGAGACAAAACAAATATACCTCTAGGAACAGTTCCAATATATGAAGCAGGAGTAGAAACAACTTCTCAAGATA
AAATTATTGTAGATATGGATGATGATATTATCTTTAAAACAATAATAAATCAAGCAAAAGAAGGTGTTGACTTTATAACA
GTACATTGTGGGATTACACAAGATGCAATAAAAGCAGTTGATGATTCAGAAAGATTAATGGGAATAGTAAGTAGGGGTGG
AGCTCTAACAGCTGCATGGATCATGCATAATGAAAGAGAAAATCCATTATATGCAGAATATGATTATTTACTAGAAATAT
GTAAAGAACATGATGTAACACTCTCTCTAGGTGATGGTTTAAGACCAGGTTGTATTCATGATGCAACTGATATTGCACAG
ATAAGAGAATTAACAACACTAGGAAGACTTGTAAAACGTTCACAAAAAGCTGGAGTACAAGTGATGGTTGAAGGACCAGG
TCATGTTCCTATAACACAAGTAAAGGCAAATATGCAAATACAAAAAACCATATGTTCAGATGCACCATTCTATGTTTTAG
GACCTTTAGTAACAGATGTTGCACCAGGTTATGATCATATTACAGCAGCAATAGGTGCAAGTATTGCAGGTGCAAGTGGG
GCTGACTTTTTATGTTATGTTACACCTGCAGAACATCTGTGTATACCAAATAAGGAACATGTAAAACAGGGTGTTATAGC
TTCAAAGATTGCTGCAGAAGTATCTGATATAGCCAAACAAATACCAAGTACAATGAAAAGAGAATATGATATGGCTGTTG
CAAGGGATAACTTTGACTGGGAAAAACAATTTGAATTGGCAATTGATGGAGAAACTGCACGTAAGTATTATGAAAGTACA
TCTACATCTGATGAGGAGATGTGTAGTATGTGTGGAGATTTCTGTGCTATAAAAATGGTTAAAGATCATGAAAAAGCAAA
TAAGAATTAG

Protein sequence :
MTQLEYARKGEITPEMEYVAKTENIDVEKLRKNIASGKVVIPKNVHNNTLPTGIGKDLHTKINANIGSSTEMEDINVELE
KLDILLKYGADAVMDLSTGPKLHEIRKAIRDKTNIPLGTVPIYEAGVETTSQDKIIVDMDDDIIFKTIINQAKEGVDFIT
VHCGITQDAIKAVDDSERLMGIVSRGGALTAAWIMHNERENPLYAEYDYLLEICKEHDVTLSLGDGLRPGCIHDATDIAQ
IRELTTLGRLVKRSQKAGVQVMVEGPGHVPITQVKANMQIQKTICSDAPFYVLGPLVTDVAPGYDHITAAIGASIAGASG
ADFLCYVTPAEHLCIPNKEHVKQGVIASKIAAEVSDIAKQIPSTMKREYDMAVARDNFDWEKQFELAIDGETARKYYEST
STSDEEMCSMCGDFCAIKMVKDHEKANKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-80 45
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-80 45
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-80 43