Gene Information

Name : guaA (SRU_2075)
Accession : YP_446181.1
Strain : Salinibacter ruber DSM 13855
Genome accession: NC_007677
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2569790 - 2571370 bp
Length : 1581 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGATAAGATCGTTGTTCTGGACTTCGGCTCGCAATACACGCAACTCATCGCGCGTCGGGTGCGGGAGACCGGAGT
GTATTCGGAGATTCGCCCCTGTACCGTCGAGGCGGACGCGATCGACGCCCTGAACCCGAGTGGCGTTATTCTGTCGGGGG
GGCCCTGTTCGGTCTACGACGAGGCGGGGCCGGCCCTTGACCCGGCCCTGCTTGAGCTGGAGCGCCCCGACGGCACCCCG
GTGCCGCTGCTGGGCATCTGCTACGGCCTGCAGGCCATGGCCCACCAGTTTGGGGGCGAGGTGGCCCGGGCCGACCGGCG
CGAGTTTGGGCGGGCGCAGCTGCAGGTGCCGCCGGACGGGCAGGAGAAGTCGCTTCTCTTCGAAGGCGTGCCGAGCGGCT
CGACCGTCTGGATGAGCCACAGCGACCACCTGACCGACCTCCCCGACGGCTACGAGGTGATTGCCCGGACCGACAACGCC
CCGGTGGCCGCCGTGCGCGACACGGACGGGCCCTACTACGGCGTGCAGTTTCACCCGGAGGTGGTGCACACGGACTACGG
CCGCCAGATTCTGGAGAACTTTGCGCACGCGATCTGCGGGTGCAGCGGCGACTGGACCCCCGCCTCGTTCGTGGAAGAGC
AGACCGAGACGATTCGGGACCGAGTGGGGGATCGCCACGTCATCCTGGGGCTCTCCGGGGGCGTGGACTCGTCGGTCGCC
GCCGCCCTTCTGCAGCGGGCCCTGGGCGATCAGCTCCACTGCATCTTCGTGAACAACGGCCTCCTGCGGAAGGGGGAGTG
GAACCAGGTGCAGGATACGTTCCGCGGCCACTTCGAGATGGACCTGCGCACCACCGACGCCACGGACCGCTTTCTGGAGC
GGCTCGACGGGGTGACGGACCCGGAGGAGAAGCGAACCATCGTCGGCAACACGTTCATCGAGGTGTTCGAGGAGCAGACC
GAGGCCATCGCCGCCGACCTGGGACACCGGCCCACCTACCTCGCCCAGGGCACGCTCTACCCCGATCTCATCGAGAGCGT
CTCGTTTAAGGGCCCGTCCGTCACCATCAAAACCCACCACAACGTCGGCGGGCTGCCCGAAGAGCTCGACTTCGACCTCA
TCGAGCCCTTCCGGGAGCTGTTCAAGGACGAGGTGCGCGAGATCGGGCGCCTGCTGGACGTGCCGGACCCAATCGTGGGG
CGGCATCCCTTCCCGGGGCCGGGCCTCGCCATCCGCATCCTCGGACAAATCACGCGGGAGCGGCTGGCCCTGCTGCGAGA
GGCGGACGCCATTTTCATCGAGGAGCTGCGCGCCAACGACCTCTACGACGAGGTCTGGCAGGCCTTCGCCGTCCTCCTGC
CGGTGCAGGCGGTGGGCGTGATGGGGGATGAGCGCACCTACGAAAACGTGTGCGCCCTGCGCGCCGTAACCAGCGTGGAC
GGCATGACGGCCGACTGGGCCCACCTCCCCCACGACTTTCTGGGGCACGTCTCGAATCGCATCGTCAACGAGGTGCCCGG
CATCAACCGGATCGTCTACGACGTGAGCTCCAAGCCGCCGGCCACCATCGAGTGGGAATAA

Protein sequence :
MHDKIVVLDFGSQYTQLIARRVRETGVYSEIRPCTVEADAIDALNPSGVILSGGPCSVYDEAGPALDPALLELERPDGTP
VPLLGICYGLQAMAHQFGGEVARADRREFGRAQLQVPPDGQEKSLLFEGVPSGSTVWMSHSDHLTDLPDGYEVIARTDNA
PVAAVRDTDGPYYGVQFHPEVVHTDYGRQILENFAHAICGCSGDWTPASFVEEQTETIRDRVGDRHVILGLSGGVDSSVA
AALLQRALGDQLHCIFVNNGLLRKGEWNQVQDTFRGHFEMDLRTTDATDRFLERLDGVTDPEEKRTIVGNTFIEVFEEQT
EAIAADLGHRPTYLAQGTLYPDLIESVSFKGPSVTIKTHHNVGGLPEELDFDLIEPFRELFKDEVREIGRLLDVPDPIVG
RHPFPGPGLAIRILGQITRERLALLREADAIFIEELRANDLYDEVWQAFAVLLPVQAVGVMGDERTYENVCALRAVTSVD
GMTADWAHLPHDFLGHVSNRIVNEVPGINRIVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-137 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-138 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-138 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-125 50