Gene Information

Name : SRU_0111 (SRU_0111)
Accession : YP_444264.1
Strain : Salinibacter ruber DSM 13855
Genome accession: NC_007677
Putative virulence/resistance : Resistance
Product : cadmium efflux ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 141539 - 144013 bp
Length : 2475 bp
Strand : +
Note : identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525

DNA sequence :
GTGCACAGTCCGTCCTCATCCGCCGTGGCCGAACAGGTTCAACTCGATCTCCCCGTCGTACTCCCACGCGTCCCCGACGC
GACGGACGCGTGCGTCGGTCGCCTCACGGACCGCCTCCGTGGGCAGCCGGGCGTAAGCAGGGCCCACGTGGTCCCCGCCA
CGAACGGCGCCCCGGACCGCCTCTGCGTGCACTACGACCCCGATACGATTGCGCGCTCTCGCATCCGGCGGCGCGTGCGG
AGTGTCGGCGCGGACCTGACCGACCGGTACGGGCACCTCTCCTGGGCCGTTGAGGGAATCTCACGTCCCCGGCGCGCCCG
GACCATCGCCAAGCGGCTGCGCCAAATCAATGGCGTGGTGGAGGCGGAGGCGCGTGCCGCCGAGCAGGTCCGCGTAGAGT
ACGACCGGTCGTCGACGAGTGCGGAGGAGATCCGCGACGTGCTCCGGTCGATGAACGTGCGGCCGCAGGGCGATCGGCTG
GCGGCGCAGGGGCTGGCGGCAGAGGCCGGCCGTGGAGACCGCGAGGAAGAACACGACCACGACCATGGTGGGATCTTCGG
CGAGAAGACGGAACTGATCGTTGCCGTCGCGGCCGGCGTGTGCGTGGCCCTGGGCGTTGGGCTCTCCGTCGTGGGCGGCA
CGCCCGGATGGGTCCCCTGGGGACTGTATGTCGGAGCCTACGCCCTTGGCGGGTACCACACCGTGCGGGAGGCGGTCGAG
ACGCTCCGGGCCGGCGAGTTTGAAGTAGATTTCCTCATGCTGGTGGCCGCGGGGGGAGCGGCGGTGCTCGGGAAATGGCT
GGAGGGGGCGTTTCTGCTGTTTCTCTTCTCCCTCGGCCACGCGCTGGAGCACTACGCGATGCGCCGCGCCCGCCGGGCCA
TCGAGTCGCTCGCCGACCTGGCCCCAGACACCGCGCTCGTCCGCCGCGACGGAGAAGAACGAGAGGTTTCCGTCGATCAG
CTGCGGGTGGGAGACACAGTCATCGTGAAGCCGAACGAGCGCATTCCGGCGGACGGATTCGTTACCCAGGGCGAGAGCGC
CGTCAACCAGGCCCCGGTGACTGGCGAGAGCGTGCCGGTGGACAAGACACCCGTTGAAACCCCGGCGGCCGTGCGGGACC
CGACGACCCTAGACGCGGCCCACCGCGTTTACGCCGGCACGATCAACGGGAGCGGCGTGCTGGAGGTACGCGTCACGAAG
CGGGCGGGCGAGTCGACCCTTTCACGAGTCGTACAGATGGTCACGGAGGCGGAAGCCGAGAAGTCCCCGACCGAACGCTT
CACCGACCGGTTTGAGCGGGTCTTCGTGCCGGCCGTCCTCGGGCTGGTGGGGCTTCTTCTCTTTGCCTGGGTGCCCCTCG
GCGAGCCCGTTGCCGACAGCTTCTACCGCGCCATGGCTGTGCTCGTGGCCGCCAGTCCGTGCGCCCTCGCCATCGCCACG
CCGAGTGCCGTGCTGAGTGCCCTGGCCCGGGCCGGGCAGGGGGGCGTGCTCGTGAAGGGGGGCGGCCCGCTCGAACACCT
CGGCCGACTCGGCGCCGTCGCGTTCGACAAGACGGGCACCCTCACGGAGGGGGCGCCCCGCGTCACGGACGTGCGTCCCC
ACAACGGAACGTCCGAAGAAGACCTTCTCCGGGCCGCCGTCGCCGCCGAACGGCTCAGCGACCACCCGCTGGCGGAGGCG
GTGGTCCAGTACGGGGACGAACACCTCGAGGGCCGCCCGCCCGAAGACGCGGCGGAAATGAAGGGCATCACGGGCCGGGG
CATTCGGGCCTCTGTGGGAGGGCGTCCCGTGCACGTCGGGAACGCGGCCCTTTTCGACGAGGTCGGCGGCCCACCGCCCC
CGGACCCGCTCCGCGACGAGGTGGAGGCGCTGGAGGCCGATGGGCGAACGACGATGATTGTCCGTCGCGGGGACACCTAC
CTCGGCGTGGTGGGCCTCGCCGATGCGCCCCGTCCAGAGGCCGCGGGCGTGGTGGAGCAGCTGCGCCGCGCGGGCATCCG
GCGGATGGTCATGCTTTCGGGCGACAACCAGCGCGTCGTGGACGCGGCGGCCGAACGGCTGGGGCTCGACGAGGCCCGGG
GCGACCTGCTGCCCAGCGACAAGGTGGACACCGTGCGGGCGCTCCGTCAGGACGAAGACGTGGCCATGGTGGGCGATGGG
GTGAACGACGCGCCCGCCATGGCGAACGCCACCGTGGGCGTTGCGATGGGGGCGGCGGGATCGGACGCGGCCCTGGAGAC
CGCCGACGTGGCCCTGATGGCCGACGACCTGTCCCAGCTGCCGTTCGCGGTGGGGCTCAGCCGACAGACCCGCCGCGTCA
TCACGCAGAACCTGTGGATTGCGCTCGGCATGGTGGCGGTGCTGGTGCCCGCTACGATTGCGGGGCTCTCCATCGGCCCG
GCCGTGGTGCTGCACGAAGGGTCGACGCTGCTCGTCGTGGGCAATGCGCTGCGGCTGCTCCGGTACGACACGTAG

Protein sequence :
MHSPSSSAVAEQVQLDLPVVLPRVPDATDACVGRLTDRLRGQPGVSRAHVVPATNGAPDRLCVHYDPDTIARSRIRRRVR
SVGADLTDRYGHLSWAVEGISRPRRARTIAKRLRQINGVVEAEARAAEQVRVEYDRSSTSAEEIRDVLRSMNVRPQGDRL
AAQGLAAEAGRGDREEEHDHDHGGIFGEKTELIVAVAAGVCVALGVGLSVVGGTPGWVPWGLYVGAYALGGYHTVREAVE
TLRAGEFEVDFLMLVAAGGAAVLGKWLEGAFLLFLFSLGHALEHYAMRRARRAIESLADLAPDTALVRRDGEEREVSVDQ
LRVGDTVIVKPNERIPADGFVTQGESAVNQAPVTGESVPVDKTPVETPAAVRDPTTLDAAHRVYAGTINGSGVLEVRVTK
RAGESTLSRVVQMVTEAEAEKSPTERFTDRFERVFVPAVLGLVGLLLFAWVPLGEPVADSFYRAMAVLVAASPCALAIAT
PSAVLSALARAGQGGVLVKGGGPLEHLGRLGAVAFDKTGTLTEGAPRVTDVRPHNGTSEEDLLRAAVAAERLSDHPLAEA
VVQYGDEHLEGRPPEDAAEMKGITGRGIRASVGGRPVHVGNAALFDEVGGPPPPDPLRDEVEALEADGRTTMIVRRGDTY
LGVVGLADAPRPEAAGVVEQLRRAGIRRMVMLSGDNQRVVDAAAERLGLDEARGDLLPSDKVDTVRALRQDEDVAMVGDG
VNDAPAMANATVGVAMGAAGSDAALETADVALMADDLSQLPFAVGLSRQTRRVITQNLWIALGMVAVLVPATIAGLSIGP
AVVLHEGSTLLVVGNALRLLRYDT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-95 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-95 42
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-94 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SRU_0111 YP_444264.1 cadmium efflux ATPase BAC0124 Protein 2e-151 64
SRU_0111 YP_444264.1 cadmium efflux ATPase BAC0298 Protein 1e-78 42
SRU_0111 YP_444264.1 cadmium efflux ATPase BAC0092 Protein 9e-91 41