Gene Information

Name : guaA (HCH_04942)
Accession : YP_436056.1
Strain : Hahella chejuensis KCTC 2396
Genome accession: NC_007645
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 5072351 - 5073931 bp
Length : 1581 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCGAAAATATTCATTCCCATCGTATTTTGATCCTGGATTTCGGTTCTCAATACACGCAGTTGATTGCTCGCCGGGT
TCGCGAAATCGGCGTTTACTGCGAAATTTACCCCTTCGACATGAGCGAAGCGGATATTCGCGAGTTCAACCCGAAAGGCG
TGATCCTGGCTGGCGGTCCCGAGTCCGTGACAGAACTGGGCTCACCGCGCGCGCCGGAATGCCTGTTCAACATGGATCTG
CCTCTGTTGGGCATTTGCTATGGCATGCAGACCATGGCGGAGCAGATGGGAGGCAAGGTTGCAGGCTCGAATGTGCGGGA
GTTCGGCTATGCGCAGGTGAAGATCGAGCGCTCCGAAGACGGTTTATTTGAAAATATCAAAGATCATGTGGCTGAAGACG
GCAAGCCCCTGCTGGACGTCTGGATGAGTCACGGCGATAAAGTGGTGGCTTTGCCGGAAGGCTTTGTGATCAGCGCTTCT
ACGCCTAGCGCGCCTATCGCCGCTATGCAGCATGAGAGCAAGCCCTGGTTTGGCGTGCAGTTCCATCCGGAAGTCACCCA
CACTCTGCAGGGGCGTCGCATGCTGGAGCGCTTCCTGGTGAATATCTGCGGATGTAAGCAACTGTGGACGCCGGGACGCA
TCATTGAAGACGCCATCACCCAGGTGCGTAATCAAGTAGGGCAGGACAAAGTGCTGTTGGGTCTATCCGGCGGCGTGGAC
TCCTCAGTGGTTGCGGCGCTGCTGCATCGCGCCATCGGCGATCAGCTGACCTGCGTGTTTGTGGATAATGGCCTGCTGCG
CCTGCATGAAGGCGATCAGGTTATGGACATGTTCGCCAAGAACATGGGCATCAAAGTCGTGCGCGCCAATGCGCAGGATC
AGTTTTTGAGCAAGCTGGCGGGAGAAAACGATCCCGAGCGCAAGCGTAAGATCATCGGCCACACCTTTATCGAAGTGTTT
GATGCGGAAGCGGCCAAAATCAAGGACGTGAAGTGGTTGGCGCAGGGCACTATCTACCCGGATGTTATCGAGTCCGCCGC
CGCGAAAACCGGTAAAGCCCATGTCATAAAATCCCACCACAATGTTGGCGGGTTACCGGAAGACATGGAAATGCAACTGG
TTGAGCCGCTGCGCGAACTGTTCAAGGACGAAGTCCGTAAGATCGGACTGGAGCTGGGACTGCCGTATGACATGGTGTAT
CGCCATCCTTTCCCGGGGCCGGGACTGGGCGTGCGCATTCTAGGCGAAGTGAAAAAAGAATATGCGGACATCCTGCGTGA
AGCGGATGCGATTTTCATAGAAGAACTGCATCGCGCGGAGTTGTATCACAAGGTGTCGCAGGCGTTTGCAGTATTCCTGC
CGGTTAAGTCTGTCGGTGTGGTGGGCGACGCCCGTCGCTATGAATACGTCATCGCGCTGAGAGCCGTAGAAACCATCGAT
TTCATGACTGCACGCTGGGCGCATCTGCCTTATGAACTATTGGAAAAGATCTCCAATCGTATTATTAATGAGATTTCCGG
CGTATCACGAGTGGTTTACGACGTTTCGTCCAAACCGCCTGCTACTATTGAGTGGGAGTAG

Protein sequence :
MSENIHSHRILILDFGSQYTQLIARRVREIGVYCEIYPFDMSEADIREFNPKGVILAGGPESVTELGSPRAPECLFNMDL
PLLGICYGMQTMAEQMGGKVAGSNVREFGYAQVKIERSEDGLFENIKDHVAEDGKPLLDVWMSHGDKVVALPEGFVISAS
TPSAPIAAMQHESKPWFGVQFHPEVTHTLQGRRMLERFLVNICGCKQLWTPGRIIEDAITQVRNQVGQDKVLLGLSGGVD
SSVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMDMFAKNMGIKVVRANAQDQFLSKLAGENDPERKRKIIGHTFIEVF
DAEAAKIKDVKWLAQGTIYPDVIESAAAKTGKAHVIKSHHNVGGLPEDMEMQLVEPLRELFKDEVRKIGLELGLPYDMVY
RHPFPGPGLGVRILGEVKKEYADILREADAIFIEELHRAELYHKVSQAFAVFLPVKSVGVVGDARRYEYVIALRAVETID
FMTARWAHLPYELLEKISNRIINEISGVSRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-126 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-126 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-126 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-113 50