Gene Information

Name : Moth_0774 (Moth_0774)
Accession : YP_429635.1
Strain : Moorella thermoacetica ATCC 39073
Genome accession: NC_007644
Putative virulence/resistance : Virulence
Product : ATPase FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 810673 - 811983 bp
Length : 1311 bp
Strand : +
Note : -

DNA sequence :
ATGAGTCTGGCTCCTGACCTGACATCTTACCGCCAGCGCCTGGCCGGCGCCACCCTCTGGCGCCGGGGCGGCAAGGTCAC
CAGGGTGACGGGCCTGACCATCGAAGCCCGGGGGCTGAAGGCGGCTATCGGCGAACTCTGCCGGATCTATAACAACGGCT
CCGGCCCCATCGTCGCCGAGGTGGTCGGCTTCCGGGAAGAAGTGACCCTCCTCATGCCCCTGGGGGAGCTGGAGGGCATT
GGCCCCGGCTGCCGGGTCATAGCCACAGGCCGCGGCCATTACATCAGGGTGGGGGAGGAACTGCTGGGCCGCGTCTTGGA
CGGCCTGGGCCGGTCCCTGGACGGCACCGTCCTGGTGAGCGGCGACCCCCAGCCGGTCAACAACCGGCCGCCCAACCCCC
TGAGCCGGCGCCGGATCAAGGAAGTCCTGGCTACGGGGGTCAAAGCCATCGACGCCCTCTTGACCTGCGGCTGCGGCCAG
CGGGTCGGCATCTTTGCCGGCAGCGGCGTTGGTAAGAGCACCCTCCTGGGGATGATCGCCCGCCACAGCACCGCTGACAT
CAACGTCATCGCCCTCATCGGCGAGCGCGGCCGGGAGGTGCGGGACTTTATCGAAGGCGACCTGGGGCCGGAGGGCCTGG
CCCGCTCCATCGTAGTGGCCGCCACCTCCGACCAGCCGGCCCTGGTGCGGATTAAGGGTGCTTTTACGGCCACGGCCATT
GCCGAGTACTTCCGCGACCAGGGGAAAAACGTCCTCCTGATGATGGACTCCCTGACCCGGTTCGCCATCGCCCAGAGGGA
GGTGGGCCTGGCCATAGGGGAGCCGCCGACAACCAGGGGTTACACCCCCTCGGTTTTTGCCTCCCTGCCGAAGCTGGTGG
AGAGGGCCGGCAACGGCGAGCGGGGTTCCATCACCGGCCTTTACACGGTTCTGGTGGAGGGCGACGATATGAACGAGCCG
GTGGCCGACACCGTCCGCGGCCTCCTGGACGGCCACATCGTCCTCTCCCGGCGCCTGGCGGCTGCGAACCACTACCCGGC
CATCGACGTCCTCCAGAGCATCAGCCGTCTAATGCCTGAGATCACCTCCCGGGAGCAACAGGAGCAGGCCGGCAAGCTGC
GGGATCTCCTGGCGGCCTACCAGGAGGCGGCCGATTTAATTGAGATCGGCGCCTACCAGGCGGGTTCCAACCCCCGGGTG
GACGCGGCCCTGAAATACCATGAGGCCATCCAGTCGTTCCTGCGCCAGGGGAAGGATGAATACTTTGCTTTCCAGGATAC
CCTGGCGGCCCTGGCGGGAATTTTAGCCTAG

Protein sequence :
MSLAPDLTSYRQRLAGATLWRRGGKVTRVTGLTIEARGLKAAIGELCRIYNNGSGPIVAEVVGFREEVTLLMPLGELEGI
GPGCRVIATGRGHYIRVGEELLGRVLDGLGRSLDGTVLVSGDPQPVNNRPPNPLSRRRIKEVLATGVKAIDALLTCGCGQ
RVGIFAGSGVGKSTLLGMIARHSTADINVIALIGERGREVRDFIEGDLGPEGLARSIVVAATSDQPALVRIKGAFTATAI
AEYFRDQGKNVLLMMDSLTRFAIAQREVGLAIGEPPTTRGYTPSVFASLPKLVERAGNGERGSITGLYTVLVEGDDMNEP
VADTVRGLLDGHIVLSRRLAAANHYPAIDVLQSISRLMPEITSREQQEQAGKLRDLLAAYQEAADLIEIGAYQAGSNPRV
DAALKYHEAIQSFLRQGKDEYFAFQDTLAALAGILA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-101 58
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-93 57
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 54
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-94 54
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-95 54
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-95 54
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-95 54
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-95 54
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-96 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-96 54
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-96 53
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-86 52
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-86 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-86 52
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-86 52
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-86 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-83 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-83 51
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-78 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-85 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-85 50
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-85 50
escN AAK26715.1 EscN Virulence LEE Protein 3e-85 50
escN AAL57542.1 EscN Virulence LEE Protein 3e-85 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-85 50
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-80 50
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-80 50
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-80 50
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-84 50
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-75 49
escN AAC31513.1 L0034 Virulence LEE Protein 8e-85 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 8e-85 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-84 49
escN AAC38383.1 EscN Virulence LEE Protein 3e-85 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-84 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-85 49
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-83 49
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-85 49
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-77 49
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-77 49
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-78 48
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-78 48
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-78 48
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-74 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-69 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 4e-73 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-73 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-73 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-73 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0192 Protein 1e-102 57
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0390 Protein 3e-100 56
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0048 Protein 2e-99 55
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG1254 Protein 2e-95 54
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG2144 Protein 9e-100 53
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG2331 Protein 2e-90 52
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0515 Protein 3e-86 52
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG2499 Protein 4e-89 50
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0812 Protein 4e-85 49
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0730 Protein 2e-85 49
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG1778 Protein 1e-70 45
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG2459 Protein 2e-70 43
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG0555 Protein 2e-73 43
Moth_0774 YP_429635.1 ATPase FliI/YscN VFG1008 Protein 2e-65 42