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Name : leuS (Moth_0568) Accession : YP_429441.1 Strain : Moorella thermoacetica ATCC 39073 Genome accession: NC_007644 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 589226 - 591715 bp Length : 2490 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGAAGCACGCTATAACTTCAAAGAGATCGAACCCAAATGGCAACGCCGCTGGGAGGCCAGCGACCTGTACCGGGTAAC GGAGGATCCCGATAAGCCCAAATTTTACTGCCTGGAGATGTTCCCCTACCCTTCTGGCAACTTGCACATGGGGCACGTCC GGAACTATTCCATCGGTGATGTAGTGGCCAGGGTCAAGCGGATGCGGGGTTATAACGTCCTCCATCCCATGGGATGGGAT GCCTTTGGCCTGCCGGCGGAAAACGCCGCCATCCACCGGGGCATCCCGCCGGCGGAGTGGACCTGGAGCAATATTGCCAA CATGCGCCGCCAGCTCCATGCCATGGGCATCAGCTACGACTGGGACCGGGAGGTGGCCACCTGCCACCCCAACTACTACC GCTGGACTCAGTGGCTTTTTCTGCAAATGTATAAACACGGCCTGGCCTACCGCAAGAAGGCTGCTGTCAACTGGTGCCCC TCCTGCGCTACCGTCCTCGCCAACGAACAGGTGGTAGACGGGGCCTGCGAGCGCTGCCATACCCCGGTAATGCGTAAAGA CCTGGAGCAGTGGTTCTTCCGCATTACCGATTATGCCGATCGCCTGCTGGAGGATTTGAAAAAGCTCCCGGGCTGGCCGG ATAAGGTAAAGATCATGCAGGAGAACTGGATTGGCAAGAGTTCCGGTGCGGAAGTAGTCTTCCGGGTGGAGGGTAGCGGC GAAGAGATTCCTGTTTTCACCACGCGACCCGACACCTTGTACGGCGTTACCTACCTGGTCCTGGCGCCCGAACACCCCCT GGTGGAGAAGTTAACCGCCGGGACGCCCTATGAGGGGCCGGTGGAGGAATTCGTCCAGGCGGCGCGCTATTTGAGCGCCC TGGATCGCACCGCCACGGAAAAGGAAAAGGAAGGTCTTTTTACAGGTGCCTATGCCATTAACCCGGTAAATAACGAACGG GTGCCCATCTGGATTGCTAACTATGTCCTCATGGAATATGGTACCGGTGCCGTCATGGGGGTACCGGCCCATGACCAGCG GGACTTTGAATTTGCTCGCAAATACGACCTGCCTGTAAAGGTCGTTATCCGGCCCGCCAGTTCGGAGTTGCCGGCCGGAG AGCTTGCAGCGGCCTATGTAGAAGACGGCATTATGGTGAATTCGGGTCCCTTTAATGGCCTGCCCAACCGGGAGGGTATT CAGAAGGTTACTGAATACCTGGAGAGTATCGGCAGGGGCAGGGCCAGGGTGAACTACCGCCTGCGGGACTGGCTCATTTC CCGCCAGCGTTACTGGGGCGCCCCCATACCCATGATCTACTGCGACCAGTGCGGTATTGTGCCGGTACCGGAGGAAGACC TGCCGGTTATCCTGCCCGAAGGAGTGGAATTCAGACCCACAGGGGAATCGCCCTTAACCTATTGCCCGGAGTTTGTTAAT ACCACCTGTCCCCGGTGTGGCGGCCCGGCCCGGCGGGAAACGGACACCATGGACACCTTCGTCTGTTCTTCCTGGTACTT CCTGCGCTATACCAGTCCCCACAGCCAGGATCGGGCCTTTGAGAGGGATAAAGTCGACTACTGGATGAACGTGGACCAGT ATATCGGCGGGGTGGAGCACGCCATCCTCCATTTGATGTACGCCCGTTTCTTCACCAAGGCCCTCCATGATTTCGGCCTG GTAGGGGTGGAGGAGCCCTTCCAGAACCTCCTGACCCAGGGAATGGTCCTTAAGGACGGCAGCAAGATGTCCAAGTCCAA AGGCAATATCGTCAGTCCTGAGGAGATAATCAATCGTTACGGGGCGGATACGGCCCGCCTCTTTATCCTCTTTGCCGCCC CGCCGGAGCGGGACCTGGAGTGGAGCGACCAGGGAGTGGAGGGTTGCTACCGCTTCTTAAACCGGGTCTGGCGCCTGGTA GGTTCCTACGCTGACGCAGTCCGCAGGGCGGGAGGCAGCCTGGAAATCAGGAGCCATGCTGACCGGGAGCTCTGGCGCCT CCTCCACGCCACCATCAAGAAAGTTACTGAGGATGTGGAGGAACGCTTTAACTTTAATACGGCCATCAGCGCTATTATGG AACTGGTCAATGGCTGTTATCGTTACCAGGACACTGTTCCGGAAGAGGAGCAGAATCTGGTTCTCATGGGAGAGGTCTTG CGCAAGCTGGTAACCCTGCTGGCTCCCTTTGCCCCCCATATTACTGAGGAACTCTGGCAGGGCCTAGGTGGACAGGAAAG CGTTCACCGGGAATCCTGGCCCCAGTACGACCCTGAGGCCCTGGTGGAAGAGGAGATCACTCTAGTAATCCAGATTAACG GTAAGGTAAAAGACCGGATGCAGGTGCCGGCAGGTTTGGCCAGGGAGAAAATCGAGGAACTCGTCCTGAACCGGGATAAG GTGGCAGCCCTGCTGGCCGGACAGCAGGTGGTAAAGGTCATTGTTGTCCCTGATAAACTTGTCAATGTGGTAGCTCGCCG GGCCAGTTGA Protein sequence : MEARYNFKEIEPKWQRRWEASDLYRVTEDPDKPKFYCLEMFPYPSGNLHMGHVRNYSIGDVVARVKRMRGYNVLHPMGWD AFGLPAENAAIHRGIPPAEWTWSNIANMRRQLHAMGISYDWDREVATCHPNYYRWTQWLFLQMYKHGLAYRKKAAVNWCP SCATVLANEQVVDGACERCHTPVMRKDLEQWFFRITDYADRLLEDLKKLPGWPDKVKIMQENWIGKSSGAEVVFRVEGSG EEIPVFTTRPDTLYGVTYLVLAPEHPLVEKLTAGTPYEGPVEEFVQAARYLSALDRTATEKEKEGLFTGAYAINPVNNER VPIWIANYVLMEYGTGAVMGVPAHDQRDFEFARKYDLPVKVVIRPASSELPAGELAAAYVEDGIMVNSGPFNGLPNREGI QKVTEYLESIGRGRARVNYRLRDWLISRQRYWGAPIPMIYCDQCGIVPVPEEDLPVILPEGVEFRPTGESPLTYCPEFVN TTCPRCGGPARRETDTMDTFVCSSWYFLRYTSPHSQDRAFERDKVDYWMNVDQYIGGVEHAILHLMYARFFTKALHDFGL VGVEEPFQNLLTQGMVLKDGSKMSKSKGNIVSPEEIINRYGADTARLFILFAAPPERDLEWSDQGVEGCYRFLNRVWRLV GSYADAVRRAGGSLEIRSHADRELWRLLHATIKKVTEDVEERFNFNTAISAIMELVNGCYRYQDTVPEEEQNLVLMGEVL RKLVTLLAPFAPHITEELWQGLGGQESVHRESWPQYDPEALVEEEITLVIQINGKVKDRMQVPAGLAREKIEELVLNRDK VAALLAGQQVVKVIVVPDKLVNVVARRAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-180 | 46 |
