Gene Information

Name : smpB (Moth_0275)
Accession : YP_429153.1
Strain : Moorella thermoacetica ATCC 39073
Genome accession: NC_007644
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 283781 - 284248 bp
Length : 468 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGGCCGCCAGGTAAAGGTCGTGACGGACAATCGCCGTGCCCGCCACGATTATTTTATTGAAGAAACCTACGAAGCGGG
CATCGCCCTGACCGGTACCGAGGTTAAATCCCTGCGCAACGGCAGGGCAAATATCAAAGATAGCTACGCGCGGGTAGAAA
ACGGCGAACTAATTCTCCACGACATGCATATCAGCCCCTATGAGCAGGGCAACCGCTTCAACCATGAACCGCGCCGGCCG
CGGCGCTTGCTCATGCACCGTTATGAGATCCAGCGCCTCTACGGCAAGGTACGGGAAAAGGGCTTGACCCTGATCCCGCT
GAAGGTGTATTTTAATGAGCGCGGCCTGGCCAAGGTAGAACTGGCCCTGGTCAAAGGTAAACGGCTTTATGACAAACGAG
AAGATATTGCCGCGCGTGATGCCCAGCGGGAAATAGCCAGGGCTTTACGCGAAAGGCAAAAAGTATAA

Protein sequence :
MGRQVKVVTDNRRARHDYFIEETYEAGIALTGTEVKSLRNGRANIKDSYARVENGELILHDMHISPYEQGNRFNHEPRRP
RRLLMHRYEIQRLYGKVREKGLTLIPLKVYFNERGLAKVELALVKGKRLYDKREDIAARDAQREIARALRERQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 8e-34 54
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-34 53
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 9e-27 41