Gene Information

Name : pyk (MCAP_0221)
Accession : YP_424208.1
Strain : Mycoplasma capricolum ATCC 27343
Genome accession: NC_007633
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 265192 - 266628 bp
Length : 1437 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGACTAAAGAAACATTACAAAAGAGAATGAAACGAACCAAAGTAATTACAACAATTGGTCCTTCAACTCACTCTGCAGA
AGCTATTAAAGAATTATTTAACAATGGAATGACAACTATTCGTTTAAATTTTTCACATGGTAGTTATGAAGAACACGGTT
ATAGAATTAAAGCTGCAAAAAAAATCTCTAAAGCTTTAAACAAGCCAATTTCAATAATATTAGATACTAAAGGTCCTGAA
ATTAGATTAGGAAAATTTAAAGATAATAAACAAGAAGTAGTAAAAGGTCAATCTATTACTATTTATACAGATAATTATTC
TTATTTAAATAAGGAATGTGTTCAAGGTGAAATGACTGTTGCTTATGATATGTCAGTTGATTTAAAGCCTGGAGATATGA
TTTTAATTGATGATGGTAAGTTAGAATTAACAGTTGATTCAGTTGAACCTCAAATCATTAAAGCAACTGCATTTAATCAT
CACATTGTAAAAACTAATAAACGTGTTAACTTACCTGGAATTGATTTTTCATTACCATTCTTATCTGAAAAAGATGAAAA
AGATATTTTATTTGGATGTGAACAAGGTGTTGATTATATAGCTGCATCATTTGTAAATACAGCTGAAAATGTAAGACAAA
TTAAAGAGATTCTAACTAAAGCTAATGCAAATCATATTCAAATTATTTCAAAAATAGAATCACAAGTTGGATTAGATAAT
ATTGATGAAATTATTGAAGAATCTGATGGAATTATGATTGCACGTGGTGATTTAGGATTAGAAATTCCATATTATGATGT
ACCTTATTGAGAAAAAATTATTATCAGAAAATGTAGAGAAAAAGGAAAGATTGTAATTGTTGCTACTCAAATGTTAGAAA
CAATGACAGAAAATCCATCACCAACTAGAGCTGAAGTAACTGATGTTTATTTTGCAACTGAACTTGGTGCTGATGCTACA
ATGTTATCTGGTGAATCAGCTGCTGGAGATTATCCGTTCTTAACAGTTCATACAATGTCAACAATTAATAAAAGAGCAGA
AGTTGAATTTTATAACAAGATTTACTATCAAGTACAATTAGATAATGCAAGAAACTCAACATCAGGACCTAGAGCTGAAA
TTGCAGACTTATTAGCTACAAAAACAAAAGATGGTGAATATAAATATGCTATTGTTTTATCAAAAACAGGTGAATTATTG
AAAACTATTTCTAAATTTAGACCAAATGTAACAATTTTAGGAGTTAGTCCAGATAAGAAATTATGAACTTCATTTGGTGT
GTGACATTCAATTTTTATGAATAAAGTTGATACTTTAGATAATTTAGATAATAATATTGAAAAATTATCAGAAATTGCTA
AATCTTGAGGAGCAAAACTTGGTGAAAAAGTTTTAGTTGTAAGAAGTACTGCTATAAAAGAAATAGAAGTTATCTAG

Protein sequence :
MTKETLQKRMKRTKVITTIGPSTHSAEAIKELFNNGMTTIRLNFSHGSYEEHGYRIKAAKKISKALNKPISIILDTKGPE
IRLGKFKDNKQEVVKGQSITIYTDNYSYLNKECVQGEMTVAYDMSVDLKPGDMILIDDGKLELTVDSVEPQIIKATAFNH
HIVKTNKRVNLPGIDFSLPFLSEKDEKDILFGCEQGVDYIAASFVNTAENVRQIKEILTKANANHIQIISKIESQVGLDN
IDEIIEESDGIMIARGDLGLEIPYYDVPYWEKIIIRKCREKGKIVIVATQMLETMTENPSPTRAEVTDVYFATELGADAT
MLSGESAAGDYPFLTVHTMSTINKRAEVEFYNKIYYQVQLDNARNSTSGPRAEIADLLATKTKDGEYKYAIVLSKTGELL
KTISKFRPNVTILGVSPDKKLWTSFGVWHSIFMNKVDTLDNLDNNIEKLSEIAKSWGAKLGEKVLVVRSTAIKEIEVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-71 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-72 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-71 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_424208.1 pyruvate kinase VFG0479 Protein 7e-72 41