Gene Information

Name : guaA (amb0732)
Accession : YP_420095.1
Strain : Magnetospirillum magneticum AMB-1
Genome accession: NC_007626
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 795433 - 796989 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCGAGCGCATCCTGATCGTCGATTTCGGCTCGCAGGTGACCCAGTTGATCGCGCGCCGCGTGCGCGAGGCCGGTGT
CTACTGCGAAATCCATCCCTTCAACCGGGTCTCCGTCGACAGCATCCGCGAGTTCGGCCCCAAGGGCGTGATCCTGTCGG
GCGGCCCGGCCTCGGTGGCCGATTTCGGCAGCCCCCGCGCCCCCCAGGGCCTGTTCGAGATGGGCCTGCCCATCCTCGGC
ATCTGCTACGGCCAGCAGACCATGTGCGAGCAGTTGGGCGGCAAGGTCGAGCCGGGCGACCACCGCGAGTTCGGCCGCGC
CATGCTCCAGGTCTCGGGCGAGCCCTGCGCCCTGTTCGACGGCATCGCCGCCAAGGGTGACGAGGTCCAGGTGTGGATGA
GCCACGGCGATCGCGTCACCGCCATTCCCCCGGGCTTCAAGGTGGTCGCCACCTCGGAAGGGGCGCCCTTCGCCGCCATT
GCCAATGCGGACAAGCGGTTCTACGGCGTGCAGTTCCACCCCGAGGTGGTGCACACCCCCATCGGCAAGCAATTGCTGTC
CAATTTCGTCCACAAGATCGTCGGCTGCGCCGGCGACTGGACCATGAAGGCCTTCCGCGCCCAGGAAATCGCCAAGGTAC
GCGCCCAGGTGGGGTCGGGCCGGGTGATCTGCGGCCTGTCGGGCGGCGTGGATTCCTCGGTGGTGGCGGCCCTGCTGCAC
GAAGCCATCGGCGATCAGCTGACCTGCGTGTTCGTCGACACTGGCTTCATGCGGGCCGGCGAGTCCGAGCAGGTGGTCAG
TGTCTTCCGCGACCGCTTCAACATCAAGCTGGTGCACAAGGACGCCTCGGGCCTGTTCCTCGACAAGCTGGCCAGTCTCA
CCGATCCCGAGAAGAAGCGCAAAATCATCGGCGCCACCTTCATCGACGTGTTCGAGGAGGAGGCCAAGGCGGTGGGCGGC
GCCGACTTCCTGGCCCAGGGCACCCTCTATCCCGACGTGATCGAAAGCGTCAGCTTCACCGGCGGGCCGTCGGTAACCAT
CAAGAGCCACCACAATGTTGGCGGCCTGCCCGAGCGCATGAACATGAAGCTGGTGGAACCGCTGCGCGAGCTGTTCAAGG
ACGAGGTCCGCGCCCTTGGCCGCGAATTGGGCCTGCCGGCCGACATGGTCGGCCGCCATCCCTTCCCCGGCCCCGGCCTG
GCCATCCGCATCCCCGGCCAGCCGCTGACCCGCGAGAACCTGGACATCCTCAGGAAGGCCGATTCCATCTATCTCGACGA
GATCCGCAAGGCGGGCCTTTATGACGAGATCTGGCAGGCCTTTGCCGTGCTGCTGCCGGTCCGCACCGTGGGCGTGATGG
GCGATTCGCGCTCCTACGACTACGCCTGCGCGCTGCGCGCTGTCACCAGCACCGACGGCATGACCGCCGATTTCTATCCC
TTCGACATGGCCTTCATCGGCCGGGTGGCCAATCGCATCATCAACGAGGTCAAGGGCATCAACCGGGTGACCTACGACAT
CACCAGCAAGCCGCCGGGCACGATTGAATGGGAGTGA

Protein sequence :
MSERILIVDFGSQVTQLIARRVREAGVYCEIHPFNRVSVDSIREFGPKGVILSGGPASVADFGSPRAPQGLFEMGLPILG
ICYGQQTMCEQLGGKVEPGDHREFGRAMLQVSGEPCALFDGIAAKGDEVQVWMSHGDRVTAIPPGFKVVATSEGAPFAAI
ANADKRFYGVQFHPEVVHTPIGKQLLSNFVHKIVGCAGDWTMKAFRAQEIAKVRAQVGSGRVICGLSGGVDSSVVAALLH
EAIGDQLTCVFVDTGFMRAGESEQVVSVFRDRFNIKLVHKDASGLFLDKLASLTDPEKKRKIIGATFIDVFEEEAKAVGG
ADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGRELGLPADMVGRHPFPGPGL
AIRIPGQPLTRENLDILRKADSIYLDEIRKAGLYDEIWQAFAVLLPVRTVGVMGDSRSYDYACALRAVTSTDGMTADFYP
FDMAFIGRVANRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-137 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-137 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-119 52