Gene Information

Name : hlgA (SAB2300)
Accession : YP_417756.1
Strain : Staphylococcus aureus RF122
Genome accession: NC_007622
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component A precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2430695 - 2431624 bp
Length : 930 bp
Strand : +
Note : -

DNA sequence :
ATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTTAATGGCCCCTTTAGCCAATCCATTTATAGAAATTTC
TAAAGCAGAAAATAAGATAGAAGATATCGGCCAAGGTGCAGAAATCATCAAAAGAACACAAGACATTACTAGCAAACGAT
TAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAAAAATATAACAAAGATGCCCTAGTTGTTAAGATGCAA
GGCTTCATCAGCTCTAGAACAACATATTCAGACTTAAAAAAATATCCATATATTAAAAGAATGATATGGCCATTTCAATA
TAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCAATTATCTTCCTAAAAATAAAATTGATTCAGCAGATG
TTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCAGCGCCATCAATCGGAGGCAGTGGCTCATTCAACTAC
TCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGTAGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGT
GAAAGCAAATTCATTCGTTACACCGAATGGTCAAGTATCTGCATATGATCAATACTTATTTGCACAAGACCCAACTGGTC
CAGCAACAAGAGACTATTTCGTCCCAGATAATCAACTACCTCCTTTAATTCAAAGTGGCTTTAATCCATCATTTATTACA
ACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGAAATCACTTACGGCAGAAACATGGATGCTACATATGC
ATACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATGCTTTTAAAAACCGAAACGTTACAGTTAAATATGAAG
TGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCTAAGTAA

Protein sequence :
MIKNKILTATLAVGLMAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQ
GFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNY
SKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPATRDYFVPDNQLPPLIQSGFNPSFIT
TLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 70
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 70
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 1e-105 70
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 70
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 1e-105 70
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 1e-105 70
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 1e-105 70
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 1e-94 66
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 1e-94 66
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 1e-97 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgA YP_417756.1 gamma-hemolysin component A precursor VFG1273 Protein 2e-141 99
hlgA YP_417756.1 gamma-hemolysin component A precursor VFG1274 Protein 5e-90 68
hlgA YP_417756.1 gamma-hemolysin component A precursor VFG1277 Protein 5e-95 66