Gene Information

Name : hysA2 (SAB2082)
Accession : YP_417540.1
Strain : Staphylococcus aureus RF122
Genome accession: NC_007622
Putative virulence/resistance : Virulence
Product : hyaluronate lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.2.1
Position : 2230263 - 2232692 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGACATATAGAATGAAGAAATGGCAAAAATTATCCACCATTACGTTATTAATGGCCGGTGGGATTACTTTTAATGATAG
TGAATTCAGAAGTGTTGATAAACATCAAATCGCTGTGGCTGATACGAATGTTCAAACGCCAAATTATGAGAAATTGAAGA
ATACATGGCTGGACGTTAACTATGGTTATGATAAGTATGATGAGAGCAATCCAGACATGAAGAAAAAGTTTGAGGCTACG
GAGAAAGAGGCAAGGAAATTACTTAGTGAGATGAAAACTGAAAGTGATAGGAAATACTTGTGGGAAAACTCAAAAGATTT
AGATACGAAGTCTGCGGATATGACTCGTACCTATCGTAATATTGAGAAAATCGCAGAAGCGATGAAGCATCCTAAAACCA
CTTTAAAAAATGACGAAAATAAGAAGAAAGTGAAAGATGCCCTTGAGTGGCTGCATAAAAATGCATATGGAAAAGAACCA
GGTAAAAAAGTTGCTGATCTGAAAACTAATTTCTCAAAATCAGCACCTCAAAAGAATACCAATTTAAATTGGTGGGATTA
TGAAATTGGAACACCTAGAGCACTAACAAATACCCTTATACTCTTAAAAGAAGATTTTACTGATGAAGAAAAGAAAAAAT
ACACTGCCCCTATTAAAACTTTCGCCCCAAAAAGTGATGAAATATTATCTTCTGTAGGAAAAGCTGAACCTGCTAAAGGC
GGAAATTTAGTAGACATTTCTAAAGTAAAACTTTTAGAAAGTATTATCGAAGAAGATAAAGATATGATGAAAAATTCAAT
AGATTCATTTAATAAAGTCTTCACTTACGTTCAAGATTCTGCCACTGATAAAGAACGTAATGGATTTTATAAAGATGGTT
CATATATCGACCATAAAGATGTCCCATACACTGGTGCTTATGGCGTTGTACTCTTAGAGGGGATTTCTCAAATGATGCCG
ATGATAAAAGAAACACCTTTTAATGATAAAACCCAAAATAATACAACCTTAACATCATGGATTGACGACGGATTTATGCC
ACTCATTTATAAAGGTGAAATGATGGATTTATCACGTGGTAGAGCCATTAGCCGAGAAAATGAAACGAGTCACTCAGCAT
CTGCAACTGTAATGAAATCATTGTTGAGATTAAGTGATGCCATGGATGAGTCTACAAAAGCTAAATATAAACAAATTGTC
AAAAACTCTGTTAAATCTGATTCAAGTTACGGCCAAAATGATACATTAAGCTCTTATTCAGACATAGATAAAATGAAGTC
TTTAATGACAGATAGCACTATTTCTACTAACGGTTTAACACAACAACTTAAAATATATAATGCCATGGATCGTGTCACCT
ATCACAATAAAGACTTAGACTTTGCATTTGGCTTAAGTATGACGTCGAAAAACGTCGCACGTTACGAAAATATCAACGGA
GAGAACTTAAAAGGTTGGCATACTGGTGCTGGAATGTCTTATTTATACAATAGCGATGTGAGACACTACCGTGATAACTT
CTGGGCAACAGCTGATATGAAACGATTAGCAGATACTACAACTTTAGAAAATGAAGAACCTAAAGGTACGGATGTTAAAA
AGTCTAGTAAAACTTTTGTAGGCGGAACAAAATTTGATGACCAACATGCTAGTATTGGAATGGATTTTGAAAATCAGGAC
AAAACTTTAACTGCCAAAAAATCATATTTCATATTAAACGATAAAATTGTCTTCTTAGGAACTGGCATTAAAACTACTGA
TTCATCAAAGAATCCAGTTACAACGATTGAAAATCGCAAAGCGCATGGGTATACGTTATATACAGACGATAAACAAACAA
CCAATTCCAATAATCAGGAAACCAATTCAGTCTTTTTAGAATCAACGAATAGCACTCAAAACAATATAGGCTATCATTTT
TTAAACAAATCGAAAATAACTGTAAAAAAAGAAAGTCATACTGGTAAGTGGAGTGATATAAATAAAAGCCAAAAGGATAC
ACAAAAAACTGATGAGTATTATGAAGTAACTCAAAAGCATTCTAATACAGATGATAAATATGCATATGTGTTGTATCCAG
GAATAACAAAAGATAATTTTAAATCCAAAGCAAGCCAAGTAACTGTCGTTAAACAAGATGATGACTTCCACGTTGTGAAA
GATAATGAATCGGTTTGGGCTGGTGTTAATTACAGTGATAGCACTCAAACTTTTGACATTAATGGTACTAAAGTCGAAGT
TAAAGCCAAAGGAATGTTTATTCTTAAAAAGAAAGATGATAACACTTATGAATGTAGCTTCTATAATCCCGAATCTACAA
ATTCCGCTTCAGATATTGAATCTAAAATTTCAATGACTGGATACTCTATTACAAACAAAAATACGTCGAATACTAATGAA
TCCGGCGTGCGCTTTGAATTAACTAAATAA

Protein sequence :
MTYRMKKWQKLSTITLLMAGGITFNDSEFRSVDKHQIAVADTNVQTPNYEKLKNTWLDVNYGYDKYDESNPDMKKKFEAT
EKEARKLLSEMKTESDRKYLWENSKDLDTKSADMTRTYRNIEKIAEAMKHPKTTLKNDENKKKVKDALEWLHKNAYGKEP
GKKVADLKTNFSKSAPQKNTNLNWWDYEIGTPRALTNTLILLKEDFTDEEKKKYTAPIKTFAPKSDEILSSVGKAEPAKG
GNLVDISKVKLLESIIEEDKDMMKNSIDSFNKVFTYVQDSATDKERNGFYKDGSYIDHKDVPYTGAYGVVLLEGISQMMP
MIKETPFNDKTQNNTTLTSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDESTKAKYKQIV
KNSVKSDSSYGQNDTLSSYSDIDKMKSLMTDSTISTNGLTQQLKIYNAMDRVTYHNKDLDFAFGLSMTSKNVARYENING
ENLKGWHTGAGMSYLYNSDVRHYRDNFWATADMKRLADTTTLENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQD
KTLTAKKSYFILNDKIVFLGTGIKTTDSSKNPVTTIENRKAHGYTLYTDDKQTTNSNNQETNSVFLESTNSTQNNIGYHF
LNKSKITVKKESHTGKWSDINKSQKDTQKTDEYYEVTQKHSNTDDKYAYVLYPGITKDNFKSKASQVTVVKQDDDFHVVK
DNESVWAGVNYSDSTQTFDINGTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSASDIESKISMTGYSITNKNTSNTNE
SGVRFELTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hysA1 YP_041274.1 hyaluronate lyase precursor 1 Virulence vSa¥â Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hysA2 YP_417540.1 hyaluronate lyase VFG1315 Protein 0.0 90