Gene Information

Name : leuS (SAB1618c)
Accession : YP_417087.1
Strain : Staphylococcus aureus RF122
Genome accession: NC_007622
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1762984 - 1765398 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAATTACAACCACAATCAAATTGAAAAGAAATGGCAAGACTATTGGGACGAAAATAAAACATTTAAAACAAATGATAA
CTTAGGTCAAAAGAAATTTTATGCTTTAGACATGTTTCCATATCCATCAGGTGCTGGTTTACATGTTGGACATCCTGAGG
GTTATACAGCAACAGATATCATTTCAAGATATAAGAGAATGCAAGGATATAATGTGTTACATCCGATGGGGTGGGATGCA
TTCGGATTACCAGCAGAGCAATATGCTTTAGACACTGGCAACGACCCACGTGAATTTACAAAGAAAAATATCCAAACTTT
TAAACGACAAATTAAAGAATTAGGGTTCAGTTATGATTGGGATCGTGAAGTTAATACAACAGATCCAGAATACTATAAAT
GGACACAGTGGATTTTCATACAGTTATATAACAAAGGTTTAGCATACGTTGATGAAGTTGCAGTTAACTGGTGTCCAGCA
TTAGGTACTGTTTTATCTAACGAAGAAGTGATTGATGGTGTCTCTGAACGTGGTGGACATCCAGTTTATCGTAAGCCGAT
GAAACAATGGGTACTTAAAATCACAGAATATGCAGATCAATTATTAGCAGATTTAGATGATTTAGATTGGCCTGAGTCTT
TAAAAGATATGCAGCGCAATTGGATTGGACGTTCTGAAGGGGCCAAAGTTTCATTTGATGTAGATAATACGGAAGGAAAA
GTAGAAGTATTTACGACTAGACCAGATACAATCTATGGTGCATCATTCTTAGTCTTAAGTCCTGAACATGCATTAGTTAA
TTCAATTACAACTGATGAATATAAAGAAAAAGTAAAAGCTTATCAAACAGAAGCTTCTAAAAAGTCAGATTTAGAACGTA
CAGATTTAGCAAAAGATAAATCAGGTGTGTTTACTGGTGCATATGCAATTAATCCTTTATCTGGTGAAAAAGTACAAATT
TGGATTGCTGATTATGTATTATCAACATATGGTACCGGAGCAATTATGGCAGTACCAGCGCATGATGACAGAGATTATGA
ATTTGCTAAAAAGTTTGATTTGCTAATCATTGAAGTCATTGAAGGTGGAAATGTTGAAGAAGCAGCATACACTGGTGAAG
GTAAACATATTAATTCTGGTGAACTTGATGGTTTAGAAAATGAAGCGGCAATTACTAAAGCTATTCAATTATTAGAGCAA
AAAGGTGCTGGCGAAAAGAAAGTTAATTACAAATTAAGAGATTGGTTATTCAGTCGTCAGCGTTATTGGGGTGAACCAAT
TCCTGTCATTCATTGGGAAGATGGAACAATGACAACTGTTCCTGAAGAAGAGCTACCATTGTTGTTACCTGAAACAGATG
AAATCAAGCCATCAGGGACTGGTGAGTCTCCACTAGCTAATATTGATTCATTTGTAAATGTTGTAGATGAAAAAACAGGT
ATGAAAGGACGTCGTGAAACAAATACGATGCCACAATGGGCAGGTAGTTGTTGGTATTATTTACGTTACATCGATCCTAA
AAATGAAAATATGTTAGCAGATCCCGAAAAATTAAAACATTGGTTACCTGTTGATTTATATATCGGTGGAGTAGAACATG
CGGTTCTTCACTTATTATATGCAAGATTTTGGCATAAAGTCCTTTATGATTTGGGCATCGTACCTACTAAAGAACCTTTC
CAAAAATTATTTAACCAAGGTATGATTTTAGGAGAAGGTAATGAGAAGATGAGTAAATCTAAAGGAAATGTAATCAATCC
TGATGATATAGTACAGTCTCATGGTGCAGATACTTTACGACTTTACGAAATGTTTATGGGGCCTTTAGATGCTGCAATTG
CATGGAGTGAAAAAGGATTAGATGGGTCTCGTCGATTCTTAGATCGCGTATGGCGTTTAATAGTAAATGAAGATGGAACA
TTGAGTTCAAAAATTGTAACTACAAATAATAAGTCTTTAGATAAAGTTTATAACCAAACTGTTAAAAAGGTAACAGATGA
CTTTGAAACATTAGGATTTAATACTGCTATTAGTCAATTAATGGTATTTATTAATGAGTGTTATAAAGTTGATGAAGTTT
ATAAACCTTACATTGAAGGTTTCGTTAAAATGTTAGCACCTATTGCACCACATATCGGTGAAGAATTATGGTCAAAATTA
GGACATGAAGAGTCTATTACGTACCAACCTTGGCCAACTTATGACGAAGCACTACTTGTAGATGATGAAGTAGAAATCGT
TGTTCAAGTTAATGGTAAATTGAGAGCTAAAATTAAAATTGCTAAAGATACATCAAAAGAAGAAATGCAAGAAATTGCCT
TATCTAATGACAATGTTAAAGCGAGTATTGAAGGTAAAGACATCATGAAAGTCATCGCTGTTCCTCAAAAATTAGTCAAT
ATTGTAGCTAAATAA

Protein sequence :
MNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPA
LGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGK
VEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQI
WIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLLIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQ
KGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTG
MKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPF
QKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLIVNEDGT
LSSKIVTTNNKSLDKVYNQTVKKVTDDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKL
GHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66