Gene Information

Name : leuS (Nmul_A0511)
Accession : YP_411211.1
Strain : Nitrosospira multiformis ATCC 25196
Genome accession: NC_007614
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 577954 - 580554 bp
Length : 2601 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAGGAAAAATATCACCCCCAGGAAATCGAGTCGGAAGCGCAGCAGTACTGGCAGCAAACCGCCGCATTCAAGGCTGT
GGAGGCGCCGGAAAAGCGGAAATACTATTGTCTTTCGATGTTTCCTTATCCCTCTGGCAAGTTGCACATGGGACATGTGC
GCAACTATACCATTGGCGATGTGCTGTCGCGCTATCACCGCATGCAGGGTTACAACGTGTTGCAGCCCATGGGCTGGGAT
GCCTTCGGCCTGCCGGCAGAGAATGCGGCAATGCAAAACAATGTACCGCCGGCAAAGTGGACCTACGACAATATCGCCTA
CATGCGCAAGCAATTGCAGAGTCTGGGGCTGGCAATGGATTGGGATCGCGAGCTTGCCACCTGCCAGCCGGATTATTACC
GGTGGAATCAGTGGCTGTTCCTGCGCATGCTGGAAAAGGGTCTGGCCTATAGAACGACGGGCATCGTAAACTGGGACCCT
GTCGACCAGACAGTACTGGCCAATGAGCAGGTAATCGACGGGCGCGGCTGGCGCACCGGAGCTCTGGTGGAAAAGCACGA
AATCCCGATGTATTACATGAAGATCACCGCGTATGCTGATGAGCTGCTGGAAGCGCTGAATGCGCTTCCGGGCTGGCCGG
AGCGGGTGAGAACGATGCAGGCCAACTGGATCGGCAAGAGCTTTGGTGTTGAAGTCCGGTTTCCTGCGGATGCCGAATCC
GGCATGCCGCAGGACTTGAAGGTTTTTACGACTCGTGCAGATACCTTGTTTGGCGTAACGTATGTAGCCGTCGCGGCTGA
GCATCCTGTCGCTCAGCACGCAGCGAAAAGTAATCCTGCCCTTGCTGCATTTATCGAAGAATGCAGGCAGGGGGCGATGA
TGGAAGCGGAACTCGCTACCCAGGAAAAGAAGGGTAGGGATACGGGTTTGTACGTTATCCACCCCCTGACCGGGGCCAGA
TTACCTGTCTGGATAGCCAATTACGTGCTGATGGGCTATGGGGAAGGGGCGGTGATGGCGGTTCCCGCTCATGATGAACG
CGATTTCGAGTTTGCTACCCAATATTCGCTGCCGATCAGGGCCGTGATCAAGCCTGTCGACTCCGGCCTGACGGTCCCCC
TTGCCCAGGCATATGTGGAACACGGCATTACGTTCGATTCCGGTGAGTTCTCCGGTCTCGCGTTCCAGCCCGCAGTGGAT
GCAATCGCTGTCGCATTGCAACAGAAGGGATTGGGCGAGAAACGCGTGCATTACCGCCTGCGTGACTGGGGCATTTCCCG
GCAGCGTTATTGGGGCTGCCCCATTCCTCTCATCTATTGCGATGCGTGCGGGGTAGTGCCGGTGCCCGATGAGCAGCTTC
CCGTGGTGCTTCCGGAAGATCTGGTGCCCGACGGCTCGGGCAACCCGCTTGCTAAAACGCCGTCATTTTACGAGTGTTCC
TGCCCGCGCTGCGGTCAGTCCGCCCGCCGGGAAACCGATACGATGGATACCTTCGTCGATTCGTCTTGGTATTACATCCG
TTATGCCTGCACCGACCAGCACCGGGCAATGGTGGATGCGCGCGTGGATTACTGGCTGCCCGTTGATCAATATATCGGCG
GCATCGAACATGCCATCCTGCATCTGCTCTACTCGCGCTTCTGGAGCAAGGTCATGCGCGATCTCGGACTGGTGTTGTTC
GACGAGCCGTTTGCCAATCTGCTGACCCAGGGCATGGTGCTCAATGAGATCATGTTCCGGAAAACGGGAAGCGGGCGCAT
CGTCTATTTCAACCCTGCGGATGTGGATATCCAGACCGACGAGCAGGGAAGACGAATCGGAGCGGTGCTGCGCGCCGACG
GCCAGCCGGTTGAAGCAGGCGGCATCGGCACGATGTCGAAATCCCGCAACAATGGCGTCGATCCGCAAAAACTCGTCGAG
CAATACGGGGCGGATACAGCCCGGCTCTTCATGATGTTTGCCAGCCCGCCCGAGCAGACTCTCGAGTGGGCGGATGCCGG
AGTAGAGGGCGCATTCCGTTTTTTGAAGCGATTATGGAAACAGGTTTACGATCATCTGCAACAAAGCGGTGTTGCGAATG
GTCCAATCCCGGTTGCAGGTCTCGGTCCTGAACTCAAGGCCTTGCGTTTTCAACTGCACCAGACCATCGCCAAGGTGGGT
GATGACCTGGGCAGGCGGCATACCTTCAATACCGCGATTGCGGCTGTAATGGAGTTGATGAACGCTCTCGGAAAATTGCA
GGATTCGAGCCCGTCTGCCCGCGGGTTGATGCAGGAAGCACTGGAAAATATTGTACTGCTGTTGTCGCCCATTGTTCCTC
ACATCTGCCATGTCCTCTGGCGGGAGCTCCGCCCGGGCACGGAGTTGCTCGATCAGCCATGGCCGCAAGCAGACGTTGCT
GCGCTCGTGCAGGATGAAATTGAGCTGATCGTTCAGGTCAATGGCAAGCTGCGGGGGAAGATACGGGTTGCCGCAGATAC
AAAACCGGTAATCGTTGAGCAGCTTGCGCTGGAGAATGAACAGGTGCGAAGGTTCATCGATGGAAAAGCAGTTAAAAAAG
TGGTGATGGTGCCAGGGAAACTGGTCAATATCGTCATTTGA

Protein sequence :
MQEKYHPQEIESEAQQYWQQTAAFKAVEAPEKRKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRYHRMQGYNVLQPMGWD
AFGLPAENAAMQNNVPPAKWTYDNIAYMRKQLQSLGLAMDWDRELATCQPDYYRWNQWLFLRMLEKGLAYRTTGIVNWDP
VDQTVLANEQVIDGRGWRTGALVEKHEIPMYYMKITAYADELLEALNALPGWPERVRTMQANWIGKSFGVEVRFPADAES
GMPQDLKVFTTRADTLFGVTYVAVAAEHPVAQHAAKSNPALAAFIEECRQGAMMEAELATQEKKGRDTGLYVIHPLTGAR
LPVWIANYVLMGYGEGAVMAVPAHDERDFEFATQYSLPIRAVIKPVDSGLTVPLAQAYVEHGITFDSGEFSGLAFQPAVD
AIAVALQQKGLGEKRVHYRLRDWGISRQRYWGCPIPLIYCDACGVVPVPDEQLPVVLPEDLVPDGSGNPLAKTPSFYECS
CPRCGQSARRETDTMDTFVDSSWYYIRYACTDQHRAMVDARVDYWLPVDQYIGGIEHAILHLLYSRFWSKVMRDLGLVLF
DEPFANLLTQGMVLNEIMFRKTGSGRIVYFNPADVDIQTDEQGRRIGAVLRADGQPVEAGGIGTMSKSRNNGVDPQKLVE
QYGADTARLFMMFASPPEQTLEWADAGVEGAFRFLKRLWKQVYDHLQQSGVANGPIPVAGLGPELKALRFQLHQTIAKVG
DDLGRRHTFNTAIAAVMELMNALGKLQDSSPSARGLMQEALENIVLLLSPIVPHICHVLWRELRPGTELLDQPWPQADVA
ALVQDEIELIVQVNGKLRGKIRVAADTKPVIVEQLALENEQVRRFIDGKAVKKVVMVPGKLVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-153 41