Gene Information

Name : murD (Nmul_A2496)
Accession : YP_413177.1
Strain : Nitrosospira multiformis ATCC 25196
Genome accession: NC_007614
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 2851469 - 2852890 bp
Length : 1422 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAACCTGCAAGGCAGAACTGTTCTGGTACTGGGCCTCGGAGAGACCGGCCTTTCCATGGCAAAATGGTTGTTTCGGCG
CGGAGCGCTGGTGCGAGCAGCTGATACCCGGAACGAGCCACCGGCCATGAGGGCGTTTAACAGCCTGCTGCCGCAGGCGG
AGGTTTTTACAGGTTCCCTGGCCGGCAGAGCCTTTTACGGCGTGGATTTAATCGCAATCAGTCCCGGTCTGCCCCTGTCG
GAGCCTCTTGTGCAGCAGGCGCTGAAAGAAGGCATCCCGGTGGTCGGGGATATGGAGCTTTTTGCCTGCGCAGTCGGAGG
CACGGGGGGGGGCATGCCAAAACTCGTCGGGATTACCGGCTCCAATGGCAAGACCACGGTGACCGCCATGACAGGGGCAA
TGTTAAAAAAAGCGGGGTGGGACGTCGAAGTAGCGGGAAATATCGGTCCTGCGGTACTGGATGCACTGATGCGCCGGGAG
GATACTGGAAAAATGCCCCAGGCGTGGGTGCTGGAGCTTTCCAGCTTCCAGCTGGAAACCACGAAGAGTCTGGGACTGGA
TGCAGCCGCAGTGCTGAATGTAAGCGAAGATCATCTTGACCGCTACGCAGGCATGCAGGAATACGCTGCTGCTAAGGCCC
GGATATTTCTTGGTGACAGCGAGGGTGTGCAAATCCTGAATGGCGATGATCCTGTCGTCCGGCAAATGACGTTAGCGGGT
AGACCTCACGTCACTTTCAGTCTTGCTACGCCACAAAGCGCCGACGATTTCGGCTTGCTTCGCGAAGGCGGAGACACCTG
GCTGATGCAGGGAGACACGCGTCTCATGGACGCGCGTGAACTCGCCATTACTGGCCGGCACAATTGCGCAAATGCACTGG
CGGCACTGGCGCTATGCCGCGCCCTGGCCGTCCCGTTCGAGCCTTTGTTACAGGCGCTCCGCGAATTCAGGGGCTTGCCC
CATCGAGTTGAAAAAGTGGCGGCTTTCAGTGGTATTACCTTCTACGACGATTCAAAAGGTACTAATGTGGGTGCAACGGT
GGCTGCTTTGAAAGGTCTGGGGCAACCCGTGGTTTTGATTGCCGGCGGAGATGGGAAGGCGCAGAATTTTTCACCCCTGG
CTGCCCCGATAGGCGAGCATGGGCGCGCGGTTGTTCTCATCGGGCGGGATGCAGAAAAAATCGCAGTGGCGATAAATGAG
TGCGGAGTGCCTCTGCATCGTGCTCAAACGATGGAAGAGGCCGTGCGGAAAAGTTTTCAGCTGGCGCGGGAGGGCGATGC
AGTCCTGATGTCGCCCGCGTGCGCAAGCTTCGATATGTTCGACAACTATGTGCATCGGGCGGAGGCGTTCGTTGCGGCGG
TAAGAAGCATGCAGGCCGCACGTGCAGGCGGTAATTCAGCTGGGGTTGCAGGACGACATTGA

Protein sequence :
MNLQGRTVLVLGLGETGLSMAKWLFRRGALVRAADTRNEPPAMRAFNSLLPQAEVFTGSLAGRAFYGVDLIAISPGLPLS
EPLVQQALKEGIPVVGDMELFACAVGGTGGGMPKLVGITGSNGKTTVTAMTGAMLKKAGWDVEVAGNIGPAVLDALMRRE
DTGKMPQAWVLELSSFQLETTKSLGLDAAAVLNVSEDHLDRYAGMQEYAAAKARIFLGDSEGVQILNGDDPVVRQMTLAG
RPHVTFSLATPQSADDFGLLREGGDTWLMQGDTRLMDARELAITGRHNCANALAALALCRALAVPFEPLLQALREFRGLP
HRVEKVAAFSGITFYDDSKGTNVGATVAALKGLGQPVVLIAGGDGKAQNFSPLAAPIGEHGRAVVLIGRDAEKIAVAINE
CGVPLHRAQTMEEAVRKSFQLAREGDAVLMSPACASFDMFDNYVHRAEAFVAAVRSMQAARAGGNSAGVAGRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 4e-63 46
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 4e-63 46