Gene Information

Name : Nmul_A2285 (Nmul_A2285)
Accession : YP_412969.1
Strain : Nitrosospira multiformis ATCC 25196
Genome accession: NC_007614
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2599705 - 2601612 bp
Length : 1908 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATGCAACAGTTTCAAGCGCGGTCCAAAGTTCGCTGCCTTTTTCGGGCAAGACTGCGCAAGTTGACGAAGGCACGGT
CAAACCTCTGCCCCGGTCACAAAAAACCTACCTGAGCGGTTCCCGCCCGGATATCCGGGTTCCCATGCGTGAAATCAGCC
AGTCCGATACGCCCGCCAGCATGGGAGCGGAAAAAAATCCGCCCATTTATGTCTATGATACTTCCGGTCCTTATACCGAC
CCGGCAATCAAAATTGACATTCGCGCCGGCTTGGCGCCGCTGCGCGAAAAGTGGATAGATGAGCGCGGAGATACGGAGAT
CCTCTCGGGTCCTGCCTCCATCTATGGCAGGCAACGTCTGAACGATCCGCGTCTCGCCGAACTGCGCTTTGACTTGAAAC
GCAGTCCCCGCCGCGCCAGAGCTGGAGCAAACGTGACACAAATGCATTATGCCCGAGGCGGCATCGTCACCCCGGAAATG
GAATTCATTGCCATACGGGAGAATCAGCGGTGCGAGCATTTGGCCGATCAACAGCGGGAAATGCTTGCGCGCCAACACCC
GGGCCAGGATTTCGGCGCGTTTCTGCCGCGCCACATCACGCCGGAGTTCGTACGCGACGAGGTCGCCAGGGGACGCGCAA
TCATTCCCGCCAACATCAATCATCCCGAATCCGAACCCATGATCATCGGGCGCAACTTTCTGGTGAAAATCAACGCAAAT
ATCGGTAATTCGGCACTAAGCTCAAGTATCCAGGAAGAAGTGGAAAAGATGACATGGGCGATACGCTGGGGAGGGGATAC
CGTAATGGATCTCTCCACGGGAAAAAACATTCATGAAACGCGCGAATGGATCATACGCAACAGTCCCGTTCCCATCGGCA
CGGTGCCGATCTACCAGGCCCTGGAAAAAGTAAATGGCAAGGCCGAAGATCTGACCTGGGAAATTTTTCGCGATACCCTG
ATAGAGCAGGCTGAACAGGGGGTGGACTATTTCACCATTCATGCCGGCGTACGGCTCGCCTATGTTCCGATGACCGCAAA
ACGGCTCACCGGTATCGTTTCCCGCGGCGGATCGATCATGGCGAAGTGGTGCCTTGCCCACCACAAAGAGAGTTTCCTGT
ATACGCAATTCGAGGAAATCTGCGAAATCATGAAGGCTTACGATGTGAGCTTCTCCCTCGGCGACGGATTGCGGCCCGGT
TCAATATACGATGCGAATGATGAAGCGCAGTTTGCGGAGCTGAAAACCCTCGGTGAACTGACGCAGATTGCCTGGAAGCA
TGATGTGCAGGTGATGATCGAAGGCCCCGGCCATGTTCCCATGCATCTCATCAAGGAGAACATGGATATGCAGCTGAAAT
ACTGCGCCGAAGCCCCGTTCTATACGTTGGGGCCGCTCACTACCGACATCGCTCCCGGGTACGATCATATTACCTCTGCC
ATCGGCGCTGCCATGATCGGCTGGTACGGTACCGCGATGTTATGTTATGTGACCCCCAAGGAGCATCTCGGCCTGCCGGA
CAAGGATGACGTCAAGGATGGCATCATCACCTATAAAATCGCTGCCCATGCCGCAGACCTGGCAAAAGGACACCCCGGCG
CCCAATTACGCGACAATGCTCTATCCAAAGCGCGCTTCGAGTTTCGCTGGGAAGATCAGTTCAACCTTGGCCTCGATCCC
GACAAGGCAAGGCAATTCCATGATGAAACTCTGCCGCAGGAAGGCGCGAAGCTCGCCCATTTCTGTTCGATGTGCGGTCC
GCATTTCTGCTCAATGAAAATCACACAGGATGTACGCGACTTTGCGGCAAGCAAAGGTGTCAGCGACCAAGAGGCCCTGG
AAAAAGGCATGGAAGAAAAAGCGAGTGAATTTGTAGCAAGGGGAACCGAGATTTACAGCAAGGTGTAA

Protein sequence :
MNATVSSAVQSSLPFSGKTAQVDEGTVKPLPRSQKTYLSGSRPDIRVPMREISQSDTPASMGAEKNPPIYVYDTSGPYTD
PAIKIDIRAGLAPLREKWIDERGDTEILSGPASIYGRQRLNDPRLAELRFDLKRSPRRARAGANVTQMHYARGGIVTPEM
EFIAIRENQRCEHLADQQREMLARQHPGQDFGAFLPRHITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINAN
IGNSALSSSIQEEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTL
IEQAEQGVDYFTIHAGVRLAYVPMTAKRLTGIVSRGGSIMAKWCLAHHKESFLYTQFEEICEIMKAYDVSFSLGDGLRPG
SIYDANDEAQFAELKTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDMQLKYCAEAPFYTLGPLTTDIAPGYDHITSA
IGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDP
DKARQFHDETLPQEGAKLAHFCSMCGPHFCSMKITQDVRDFAASKGVSDQEALEKGMEEKASEFVARGTEIYSKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 76
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 76
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74