Gene Information

Name : Nmul_A0180 (Nmul_A0180)
Accession : YP_410880.1
Strain : Nitrosospira multiformis ATCC 25196
Genome accession: NC_007614
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 190904 - 192274 bp
Length : 1371 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATTCATCTGTTACGTACGCAACTGGATCACGTTGCCAGGCTTCTTGCCGAGCGTAACTACGTTTTTCCTCT
TGCTGAATTCAGTGCCCTGGAAGCGGAACGAAAAAATCTTCAAACCTCCACCCAGGAATTGCAAGCGCGCCGCAATGGCG
CGTCGAAGCAGATCGGCAATGCCAAGAGCAGGGGCGAAGATGCCAGCGCGATTCTCGCAGAGGTCGCTCATCTGGGTGAT
GAGCTGAAGCAGGCGGAATCCCGGCTGGATCAGGTACAGGCTGCGCTGCAGCACATCCTGCTGCAAATACCCAACCTGCC
GCACAGCAGCGTGCCGGAGGGCAGAAGCGAATCGGATAACAGGGAAGTGCGACGTTGGGGAACTCCACCCACATTTGATT
TCAGCCCGGCCGATCATGTGAGCATAGGCGAGCGACTGGGATTACTGGATTTTCCCACTGCTGCCAAGATCAGCGGCGCC
CGCTTCAGCCTGCTGACAGGCTCGCTTGCGCACCTGCATCGCGCACTGGCTCAATTCATGCTCGATGTTCATGTCCGCGA
ACATGGGTATACAGAGACCTACGTGCCCTATCTGGTCAATGCGGAAAGTTTGCGGGGTACCGGCCAGCTGCCGAAGTTCA
AGGAAGATTTGTTCGAGGTTCCACGAAGAAAAACAGCCGAACCTTTCCTGGAAAACCAGCCGGTTGCTGCAACGCTGCCA
TCGAATAGCAATAGTCCGCAAGGAGGACAGGACGATGATGACTTATACTTGATTCCCACTTCCGAGGTTCCGCTGAGCAA
CATCGTGCGTGACCGCATCGTCGATCCTGAATTGCTGCCTATCAAGCTTACTGCGCATACCCCCTGCTTTCGCTCCGAAG
CGGGGAGCTACGGCAGGGATACTCGCGGAATGATCCGGCAGCATCAGTTCGAGAAGGTGGAACTGGTGCAAATTGTCCAT
CCTGCACACTCCTATAAAGCGCTGGAAGAGCTGACAGGCCATGCCGAAGCAATTCTTCAGAAGCTGAAACTGCCTTACCG
GGTGATGGCGTTATGCACGGCCGACATGGGGTTTGCCGCCGCCAAGACGTACGACATCGAAGTATGGTTACCGCAGCAAG
GCACCTATCGGGAAATTTCCTCATGCAGTAACTGTGAAGCATTCCAGGCACGGCGCATGCAGGCACGTTTTCGCAATGAG
AAAGGCAAGCCGGAACTGTTGCACACACTCAACGGGTCGGGTCTGGCGGTGGGACGGACGCTGGTGGCGATACTGGAAAA
TTTCCAGAATGCAGACGGCAGCGTATCGATTCCCAAGGTTTTGCAAGGCTATATGGGCGGAACCGAGCGGCTTGTGCCCC
ATAACGCATAA

Protein sequence :
MLDIHLLRTQLDHVARLLAERNYVFPLAEFSALEAERKNLQTSTQELQARRNGASKQIGNAKSRGEDASAILAEVAHLGD
ELKQAESRLDQVQAALQHILLQIPNLPHSSVPEGRSESDNREVRRWGTPPTFDFSPADHVSIGERLGLLDFPTAAKISGA
RFSLLTGSLAHLHRALAQFMLDVHVREHGYTETYVPYLVNAESLRGTGQLPKFKEDLFEVPRRKTAEPFLENQPVAATLP
SNSNSPQGGQDDDDLYLIPTSEVPLSNIVRDRIVDPELLPIKLTAHTPCFRSEAGSYGRDTRGMIRQHQFEKVELVQIVH
PAHSYKALEELTGHAEAILQKLKLPYRVMALCTADMGFAAAKTYDIEVWLPQQGTYREISSCSNCEAFQARRMQARFRNE
KGKPELLHTLNGSGLAVGRTLVAILENFQNADGSVSIPKVLQGYMGGTERLVPHNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-93 52