Gene Information

Name : smpB (Nmul_A1203)
Accession : YP_411898.1
Strain : Nitrosospira multiformis ATCC 25196
Genome accession: NC_007614
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1389705 - 1390148 bp
Length : 444 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGCATCGTCCAGAATAAGAAAGCTTTCCATGACTATTTTATCGAGGAGAAGCATGAAGCAGGGGCAGTTCTGGAAGG
ATGGGAAGTCAAGGCGATTCGCGCGGGACGAGCGCAGCTGAAGGAAGCCTATGTCATTATCCGGAACGGTGAATTGTTTC
TCATCGGGTGTCATGTCAGTCCCTTGCTGGCAGCTTCCACCCACATCCAGCCCGACCCGGTTCGTACGCGCAAGCTGTTG
TTGCATGCTGAGGAAATCAAACGGCTTATCGGCAAAGTGGAACGGGCGGGCTACACCCTGGTTCCACTGGATATCCATTA
TAAGAAAGGGCGAATCAAGCTTGAAATCGGTCTTGCAAAGGGCAAGAAGCAGCATGACAAACGCGAATCCGAGAAGCAGA
AAGAGTGGGAACGCGACAAGCAGCGGTTGATGCGTCCAAAATAA

Protein sequence :
MSIVQNKKAFHDYFIEEKHEAGAVLEGWEVKAIRAGRAQLKEAYVIIRNGELFLIGCHVSPLLAASTHIQPDPVRTRKLL
LHAEEIKRLIGKVERAGYTLVPLDIHYKKGRIKLEIGLAKGKKQHDKRESEKQKEWERDKQRLMRPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-34 50
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-18 46
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-24 44