Gene Information

Name : serS (SBO_0826)
Accession : YP_407326.1
Strain : Shigella boydii Sb227
Genome accession: NC_007613
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 842267 - 843559 bp
Length : 1293 bp
Strand : +
Note : also charges selenocystein tRNA with serine; catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATCTGCTGCGTAATGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGCTGGGCGCTCTCGAAGAGCGTCGTAAAGTATTGCAGGTCAAAACGGAAAACCTGCAAGCGGAGCGTAACTCCC
GATCGAAATCCATTGGCCAGGCGAAAGCGCGCGGGGAAGATATCGAGCCTTTACGTCTGGAAGTGAACAAACTGGGCGAA
GAGCTGGATGCAGCAAAAGCCGAGCTGGATGCTTTACAGGCTGAAATTCGCGATATCGCGCTGACCATCCCTAACCTGCC
TGCAGATGAAGTGCCGGTAGGTAAAGACGAAAATGACAACGTTGAAGTCAGCCGCTGGGGTACCCCGCGTGAGTTTGACT
TTGAAGTTCGTGACCACGTGACGCTGGGTGAAATGCACTCTGGCCTCGACTTTGCAGCTGCAGTTAAGCTGACTGGTTCC
CGCTTTGTGGTAATGAAAGGGCAGATTGCTCGCATGCACCGCGCACTGTCGCAGTTTATGCTGGATCTGCATACCGAACA
GCATGGCTACAGTGAGAACTATGTTCCGTACCTGGTTAACCAGGACACGCTGTACGGTACGGGTCAGCTGCCGAAATTTG
CTGGCGATCTGTTCCATACTCGTCCGCTGGAAGAAGAAGCAGACACCAGTAACTATGCGCTGATCCCAACGGCAGAAGTT
CCGCTGACTAACCTGGTGCGCGGTGAAATCATCGATGAAGATGATCTGCCAATTAAGATGACCGCCCACACCCCATGCTT
CCGTTCTGAAGCCGGTTCATATGGTCGTGACACCCGTGGTCTGATCCGTATGCACCAGTTCGACAAAGTTGAAATGGTGC
AGATCGTGCGCCCGGAAGACTCAATGGCGGCGCTGGAAGAGATGACTGGTCATGCAGAAAAAGTCCTGCAGCTGCTGGGC
CTGCCGTACCGTAAAATCATCCTTTGTACCGGCGACATGGGCTTTGGCGCTTGCAAAACCTATGACCTGGAAGTATGGAT
CCCGGCACAGAACACCTACCGTGAGATCTCTTCCTGCTCCAACGTTTGGGATTTCCAGGCACGTCGTATGCAGGCACGTT
GCCGCAGCAAGTCGGACAAGAAAACCCGTCTGGTTCATACCCTGAACGGTTCTGGTCTGGCTGTTGGTCGTACGCTGGTT
GCAGTAATGGAAAACTATCAGCAGGCTGATGGTCGTATTGAAGTACCAGAAGTTCTGCGTCCGTATATGAACGGACTGGA
ATATATTGGCTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEV
PLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-102 57