Gene Information

Name : intB (SBO_4164)
Accession : YP_410419.1
Strain : Shigella boydii Sb227
Genome accession: NC_007613
Putative virulence/resistance : Unknown
Product : prophage P4 integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4215530 - 4216723 bp
Length : 1194 bp
Strand : -
Note : Code: L; COG: COG0582

DNA sequence :
ATGTCCTTACTTGTAAAACCTGGCGGTTCAAAGTATTGGCGATTTCGTTTCCGTTTTGGCGGTAAACAACATTTGATGGC
GTTCGGCGTTTACCCGGATGTTTCGCTGGCGGATGCGCGGAAGAAAAGGGAAGAGGCCAGAAAGCTGGTAGCTGCTGGTA
TCGATCCTCGTGAGCATAAGCGTGCTGTGAAAGAAGAGCAGGCGAAAGAGATTATTACTTTCGAGAAGGTTGCCAGAGAG
TGGCTCGTAACCAACCAAAAATGGTCGGAAGAGCATGCTAATCGTGTAAAAAAGAGCCTGGAGGACAATATCTTCCCGGC
AATTGGTTCCCACAATATTGCTGAACTGGGCACCCGCGATCTGTTAATTCCTATTAAAGCCGTGGAGAAATCCGGACGTC
TTGAAGTGGCTTCCCGCCTTCAACAGCGCACCACGGCCATCATGCGTTATGCAGTGCAAAGCGGGTTAATTGATTACAAT
CCGGCGCAAGAGATGGCGGGGGCGGTAGCTTCCAGTAATCGACAGCATCGTCCGGCGCTGGAGTTAAAGCGTATCCCGGA
ATTACTCCAGAAAATCGATGAATACACCGGCAGGCCACTAACCCGCTGGGCAACCGAACTTACCCTGCTTATTTTTATTC
GATCCAGTGAGCTGCGTTTTGCTCGCTGGTCAGAAATCGATTTTGAAACGTCAATGTGGACCATCCCGCCTGAGCGAGAA
CCTATTCCCGGTGTGAAACATTCTCAGCGAGGAGCAAAGATGCGTACACCTCATCTGGTGCCGCTTTCAAAGCAGGCGCT
AGCGATCCTGAAGCAGATAAAACAGTTCTGTGGCGAACATGAGCTGATTTTTATTGGCGATCACGATCCGAGTAAGCCCA
TGAGTGAAAACACGGTGAACAGTGCATTGCGGGTGATGGGCTATGACACCAAGGTTGAGGTTTGCGGCCACGGCTTCCGC
ACTATGGCCTGTAGCTCATTGATTGAGTCAGGGTTATGGTCGAAGGATGCGGTGGAAAGGCAGATGAGCCATATGGAACG
CAATTCGGTGAGGGCGGCGTATATCCATAAAGCGGAACATCTGGATGAGCGCAAGCTGATGTTGCAGTGGTGGGCTGATT
TTCTGGATGCGAACCGGGAGAAGGGGATTACGCCGTTTGACTATGCGAAGATCAATCGGGGTAATGGCGAGTGA

Protein sequence :
MSLLVKPGGSKYWRFRFRFGGKQHLMAFGVYPDVSLADARKKREEARKLVAAGIDPREHKRAVKEEQAKEIITFEKVARE
WLVTNQKWSEEHANRVKKSLEDNIFPAIGSHNIAELGTRDLLIPIKAVEKSGRLEVASRLQQRTTAIMRYAVQSGLIDYN
PAQEMAGAVASSNRQHRPALELKRIPELLQKIDEYTGRPLTRWATELTLLIFIRSSELRFARWSEIDFETSMWTIPPERE
PIPGVKHSQRGAKMRTPHLVPLSKQALAILKQIKQFCGEHELIFIGDHDPSKPMSENTVNSALRVMGYDTKVEVCGHGFR
TMACSSLIESGLWSKDAVERQMSHMERNSVRAAYIHKAEHLDERKLMLQWWADFLDANREKGITPFDYAKINRGNGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 4e-160 83
int AAK00456.1 Int Not tested SHI-1 Protein 7e-135 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 4e-135 68
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 4e-135 68
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 4e-132 67
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 7e-135 67
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-134 67
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 9e-135 67
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-133 67
int AAK16198.1 Int Not tested PAI-I AL862 Protein 9e-134 67
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 9e-134 67
int CAC81896.1 integrase Not tested LEE II Protein 2e-132 66
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-132 66
int AAL51003.1 CP4-like integrase Not tested LEE Protein 7e-133 66
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-132 66
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 6e-133 66
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 7e-133 66
int AAL51028.1 CP4-like integrase Not tested LEE Protein 6e-133 66
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 7e-133 66
int-phe AAL60261.1 Int-phe Not tested LEE Protein 6e-133 66
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 4e-131 66
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 4e-132 65
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-125 64
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-125 64
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 1e-82 58
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 6e-111 58
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 3e-95 57
int YP_002346908.1 integrase Not tested HPI Protein 2e-103 57
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 2e-103 57
int2 NP_993013.1 integrase Not tested HPI Protein 2e-103 57
int CAA21384.1 - Not tested HPI Protein 2e-103 57
int CAA08754.1 integrase Not tested HPI Protein 5e-104 57
int CAB59974.1 integrase Not tested HPI Protein 1e-104 57
unnamed AAD17660.1 unknown Not tested HPI Protein 3e-100 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 6e-107 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 6e-107 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 1e-96 52
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 4e-69 42
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-72 42
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-72 42
int ACU09430.1 integrase Not tested LEE Protein 1e-72 42
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-72 42
int AAD44730.1 Int Not tested SHI-2 Protein 6e-74 42
aec33 AAW51716.1 Int Not tested AGI-3 Protein 5e-74 42
int CAC39282.1 integrase Not tested LPA Protein 5e-74 42
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 9e-74 42
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-73 42
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-73 42
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intB YP_410419.1 prophage P4 integrase VFG1536 Protein 2e-160 83
intB YP_410419.1 prophage P4 integrase VFG0626 Protein 2e-135 68
intB YP_410419.1 prophage P4 integrase VFG1693 Protein 7e-133 66
intB YP_410419.1 prophage P4 integrase VFG0783 Protein 7e-73 42
intB YP_410419.1 prophage P4 integrase VFG0598 Protein 5e-74 42