Gene Information

Name : yhcI (SBO_3167)
Accession : YP_409495.2
Strain : Shigella boydii Sb227
Genome accession: NC_007613
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 3172124 - 3172999 bp
Length : 876 bp
Strand : +
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGACCACGTTGGCGATTGATATCGGCGGTACTAAACTTGCCGCCGCGCTGATTGGCGCTGACGGGCAGATCCGCGATCG
CCGAGAACTTCCGACACCAGCCAGCCAGACTCCGCAGGCGTTGCGTGATGCCTTAGCCGCGTTAGTCGCCCCGTTGCAAG
CTCATGCGCAGCAGGTTGCCATCGCTTCAACCGGAATTATTCGCGACGGCAGCTTGCTGGCGCTGAATCCGCATAATCTT
GGTGGATTGCTACACTTTCCGTTAGTCAAAACGCTGGAACAACTTTCCAATTTGCCGACCATTGCCATTAACGACGCGCA
GGCCGCAGCATGGGCAGAGTATCAGGCGCTGGAAGGCGATATAACCGATATGGTGTTTATCACCGTTTCCACTGGCGTCG
GCGGCGGTGTAGTGAGCGGCGGTAAACTGCTTACCGGCCCTGGCGGTCTGGCGGGGCACATCGGGCATACGCTTGCCGAT
CCACACGGCCCAGTCTGCGGCTGTGGACGCACAGGTTGCGTGGAAGCGATTGCTTCTGGTCGCGGTATTGCAGCGGCAGC
GCAAGGTGAACTCATGGGCGCGGATGCGAGAACTATTTTCACACGCGCCGGGCAGGGCGACGAGCAGGCGCAGCAACTGA
TTCACCGCTCCGCACATGTGCTGGCAAGGCTGATCGCTGATATTAAAGCCACAACTGATTGCCAGTGCGTGGTGGTCGGT
GGCAGCGTTGGTCTGGCAGAAGGGTATCTGGCGTTGGTGGAAACGTATCTGGCGCAGGAGCCAGCGGCATTTCATGTTGA
TTTACTGGCGGCGCACTACCGCCACGATGCAGGTTTACTTGGGGCTGCGCTGTTGGCCCAGGGAGAAAAATTATGA

Protein sequence : 
MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPQALRDALAALVAPLQAHAQQVAIASTGIIRDGSLLALNPHNL
GGLLHFPLVKTLEQLSNLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
PHGPVCGCGRTGCVEAIASGRGIAAAAQGELMGADARTIFTRAGQGDEQAQQLIHRSAHVLARLIADIKATTDCQCVVVG
GSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 3e-39 52
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-28 41
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-28 41
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 3e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yhcI YP_409495.2 N-acetylmannosamine kinase VFG1115 Protein 1e-28 41