Gene Information

Name : yfcU (SBO_2376)
Accession : YP_408767.1
Strain : Shigella boydii Sb227
Genome accession: NC_007613
Putative virulence/resistance : Virulence
Product : PapC-like porin protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2362690 - 2365332 bp
Length : 2643 bp
Strand : -
Note : involved in fimbrial biogenesis; Code: NU; COG: COG3188

DNA sequence :
ATGCCTGACCATTCTCTTTTTCGATTACGGATTCTTCCGTGGTGCATTGCGCTGGCAATGTCAGGGAGTTATAGCAGTGT
CTGGGCTGAAGACGACATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACAAAAATTGATCTGAAGCGTTTTT
CCAGCCAGGGATATGTTGAGCCCGGAAAATACAATTTACAGGTTCAACTAAATAAACAGCCATTGGCGGAAGAGTACGAT
ATTTACTGGTATGCTGGTGAAGATGACGCGAGCAAAAGCTATGCTTGTCTGACACCGGAACTGGTAGCGCAGTTTGGTTT
AAAAGAAGACGTGGCGAAAAATCTGCAATGGAGCCACGATGCTAAATGCCTGAAATCCGGTCAACTGGAAGGCATGGAAA
TTAAGGCTGATTTAAGCCAGTCCGCATTAGTCATTTCACTGCCACAGGCTTACCTCGAATATACTTATCCCGACTGGGAT
CCGCCTTCACGTTGGGATGACGGCATCTCCGGGATCGTCGCGGACTACAGCATCAACGCACAAACCCGGCACGAAGAAAA
TGGCGGTGATGATAGTAACGAGATCAGCGGCAACGGGACGGTCGGGGTTAACCTGGGGCCGTGGCGTATGCGTGCTGACT
GGCAGACTAACTATCAACATACTCGCAGTAATGATGACGATGAATTCAGCGGCGATGAAACTCAAAAAAAATGGGAGTGG
AGTCGCTACTATGCCTGGCGGGCGTTACCATCATTAAAAGCCAAACTGGCGCTGGGCGAGGATTACCTCAGATCCGATAT
TTTTGATGGTTTTAACTATGTTGGTGGTAGTGTCAGTACTGACGATCAAATGTTGCCTCCCAATCTGCGCGGCTACGCGC
CAGACATTTCCGGCGTGGCACACACCACAGCAAAAGTGACCGTCAGCCAGATGGGGCGTGTGATTTACGAAACGCAGGTT
CCGGCTGGACCGTTTCGTATTCAGGATCTTGGTGATTCTGTCTCCGGTACGTTGCATATTCGCATTGAAGAACAGAACGG
CCAGGTGCAGGAATATGACATCAGCACCGCCTCGATGCCATACCTCACTCGTCCAGGTCAGATTCGCTATAAGATCATGA
TGGGCCGTCCGCAAGAGTGGGGACACCATGTCGAGGGTGAATTTTTTTCTGGTGCTGAAGCTTCCTGGGGGATCGCTAAC
GGCTGGTCGTTATATGGCGGCGCACTGGGAGATGAAAACTATCAGTCTGCGGCGCTTGGCGTCGGTCGCGATTTGTCTAC
ATTCGGCGCGGTCGCGTTTGATGTTACTCACTCGCACACCAAACTGGATAAAGACACCGCTTATGGCAAAGGTTCGCTGG
ACGGTAACTCCTTCCGTGTGAGTTATTCCAAAGACTTTGACCAGCTCAACAGCCGCGTTACTTTTGCTGGATATCGCTTC
TCGGAAGAGAACTTTATGACCATGAGCGAGTATCTGGATGCCAGTGACAGCGGAATGGTACGCACGGGCAACGACAAAGA
GATGTGCACCGCCACTTATAACCAGAACTTCCGCGATGCGGGTGTTTCGGTTTATCTCAACTATACCCGCCATACCTACT
GGGATCGCGAGGAGCAGATAAACTACAACATCATGCTCTCGCACTATTTCAATATGGGCAGTATTCGTAATGTCAGCATC
TCGATGACTGGCTACCGTTACGAGTATGACAACCAGGCCGACAAAGGCATGTACATTTCGCTCAGTATGCCGTGGGGCGA
CAACAGTACCGTTAGCTATAACGGTAACTATGGCAGTGGGACGGACAGCAGTCAGGTCGGTTATTTCAGCCGTGTCGATG
ACGCGACTCACTATCAGTTGAACGTCGGCACCAGTGACAAACACACCAGCGTTGACGGCTATTACAGCCATGATGGTTCG
CTGGCGCAGGTTGACCTCAGTGCGAACTACCATGAAGGGCAATACACCTCTGCGGGCTTGTCGTTACAGGGCGGCGCAAC
GCTTACTGCCCACGGTGGCGCACTTCACCGTACCCAGAATATGGGCGGGACACGCTTGTTGATTGATGCCGATGGCGTTG
CCGATGTTCCGGTGGAAGGTAACGGGGCTGCTGTTTATACCAATATGTTTGGTAAAGCCGTCGTTTCTGACGTCAATAAC
TATTACCGCAATCAGGCGTATATCGACCTCAACAGATTGCCTGAAAACGCTGAAGCAACCCAGTCGGTGGTGCAAGCCAC
GCTAACTGAAGGTGCCATTGGCTACCGTAAATTTGCTGTCATTAGCGGACAAAAAGCGATGGCGGTGCTGCGCCTGAGCG
ACGGCAGCCATCCTCCGTTTGGCGCAGAAGTAAAAAATGATAACGAGCAGACAGTGGGCCTTGTCGATGATGACGGCAAT
GTTTATCTGGCTGGGGTGAAACCTGGCGAACACATGAGTGTGTTCTGGAGTGGTGTTGCGCATTGCGATATCAACCTGCC
GGACCCGCTGCCTGCCGATCTGTTTAACGGCTTGTTACTACCATGCCAGCATAAAGGCAATGTAGCACCTATCACTTCGC
CGGCGGTCAAACCGGCGATTCAGGAACAGACACAGCGGGTGACGCCAACGGAACCTCCGACTTCAATTTCAGTAAACCAG
TAA

Protein sequence :
MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYD
IYWYAGEDDASKSYACLTPELVAQFGLKEDVAKNLQWSHDAKCLKSGQLEGMEIKADLSQSALVISLPQAYLEYTYPDWD
PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDEFSGDETQKKWEW
SRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQV
PAGPFRIQDLGDSVSGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQIRYKIMMGRPQEWGHHVEGEFFSGAEASWGIAN
GWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRF
SEENFMTMSEYLDASDSGMVRTGNDKEMCTATYNQNFRDAGVSVYLNYTRHTYWDREEQINYNIMLSHYFNMGSIRNVSI
SMTGYRYEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGTSDKHTSVDGYYSHDGS
LAQVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNN
YYRNQAYIDLNRLPENAEATQSVVQATLTEGAIGYRKFAVISGQKAMAVLRLSDGSHPPFGAEVKNDNEQTVGLVDDDGN
VYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPITSPAVKPAIQEQTQRVTPTEPPTSISVNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 2e-150 44
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 2e-150 44
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 2e-150 44
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 1e-150 43
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 2e-149 43
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 2e-149 43
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 1e-155 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcU YP_408767.1 PapC-like porin protein VFG0884 Protein 8e-151 44
yfcU YP_408767.1 PapC-like porin protein VFG0895 Protein 7e-151 44
yfcU YP_408767.1 PapC-like porin protein VFG1548 Protein 8e-151 43