Gene Information

Name : pepA (SDY_4284)
Accession : YP_405675.1
Strain : Shigella dysenteriae Sd197
Genome accession: NC_007606
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 4012736 - 4014247 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGTCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACATTGTTGCTGCACCATGTGCCAAACGTGCTTTCTGAACGCATCCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAGCGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCAATGGA
AGCGGTCTGCTTTCTGACTGAACTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACGGCAA
AAGAGACGCTCTACAGTTTCGATCAGCTGAAAACGAACAAGAGCGAACCGCGTCGTCCGCTGCGTAAAATGGTGTTCAAC
GTGCCGACCCGCCGTGAACTGACCAGCGGTGAGCGCGCGATCCAGCACGGTCTGGCGATTGCCGCCGGGATTAAAGCCGC
GAAAGATCTCGGTAATATGCCGCCGAATATCTGTAACGCCGCTTATCTCGCCTCTCAGGCGCGCCAGCTGGCTGACAGCT
ACAGCAAGAATGTCATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGGATGCATTCTTATCTGGCGGTCGGT
CAGGGTTCGCAGAACGAATCGCTGATGTCGGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCACGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCTGGCGGTATCTCCATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGTGCGGCAGCGGTCTACGGCGTGATGCGTATGGTCGCGGAGCTACAACTGCCGGTTAACGTTATCGGCGTGCTG
GCAGGCTGCGAAAACATGCCTGGCGGTCGTGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTTGA
AGTGCTGAATACCGACGCTGAAGGCCGCCTGGTACTGTGCGACGTATTAACTTACGTTGAGCGTTTTGAGCCGGAAGCGG
TGATTGATGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTGGGTCATCATATTACTGGTCTGATGGCGAACCACAAT
CCGCTGGCCCATGAACTGATTGCCGCATCTGAACAATCCGGTGACCGCGCATGGCGTTTACCGCTGGGTGACGAGTATCA
GGAACAGCTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TATCGCGCTTTACCCGTAAGTATAACTGGGCGCACCTAGATATCGCCGGTACTGCCTGGCGTTCTGGTAAGGCGAAAGGC
GCAACCGGTCGCCCGGTGGCGTTGCTGGCACAGTTCCTGCTAAACCGCGCCGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPVNVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 3e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 3e-90 55