Gene Information

Name : tktA (SDY_3141)
Accession : YP_404646.1
Strain : Shigella dysenteriae Sd197
Genome accession: NC_007606
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2909549 - 2911540 bp
Length : 1992 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCTCACGTAAAGAGCTTGCCAATGCTATTCGTGCGCTGAGCATGGACGCAGTACAGAAAGCCAAATCCGGTCACCC
GGGTGCCCCTATGGGTATGGCTGACATTGCCGAAGTCCTGTGGCGTGATTTCCTGAAACACAACCCGCAGAATCCGTCCT
GGGCTGATCGTGACCGCTTCGTGCTGTCCAACGGACACGGCTCCATGCTGATCTACAGCCTGCTGCACCTCACCGGTTAC
GATCTGCCGATGGAAGAACTGAAAAACTTCCGTCAGCTGCACTCTAAAACTCCGGGCCACCCGGAAGTGGGTTACACCGC
TGGTGTGGAAACCACCACCGGTCCGCTGGGTCAGGGTATTGCCAACGCAGTCGGTATGGCGATTGCAGAAAAAACGCTGG
CGGCGCAGTTTAACCGTCCGGGCCACGACATTGTCGACCACTACACCTACGCCTTCATGGGCGACGGCTGCATGATGGAA
GGCATCTCCCACGAAGTTTGCTCTCTGGCGGGTACGCTGAAGCTGGGTAAACTGATTGCATTCTACGATGACAACGGTAT
TTCTATCGATGGTCACGTTGAAGGCTGGTTCACCGACGACACCGCAATGCGTTTCGAAGCTTACGGCTGGCACGTTATTC
GCGACATCGACGGTCATGACGCAGCATCCATCAAACGCGCAGTAGAAGAAGCGCGCGCAGTGACTGACAAACCGTCCCTG
CTGATGTGCAAAACCATCATCGGTTTCGGTTCCCCGAACAAAGCCGGTACTCACGACTCCCACGGTGCGCCGCTGGGTGA
TGCAGAAATCGCTCTGACCCGCGAACAGCTGGGCTGGAAATACGCGCCGTTCGAAATCCCGTCTGAAATCTATGCGCAGT
GGGATGCGAAAGAAGCAGGCCAGGCGAAAGAAGCAGCCTGGAATGAGAAATTCGCGGCTTACGCCAAAGCCTTCCCGCAG
GAAGCGGCTGAATTCACCCGTCGTATGAAAGGTGAAATGCCGTCTGACTTCGACGCGAAAGCGAAAGAGTTCATTGCTAA
ACTGCAGGCTAATCCGGCGAAAATCGCCAGCCGTAAAGCGTCGCAGAATGCTATCGAAGCGTTCGGTCCGCTGTTGCCGG
AATTCCTCGGCGGCTCCGCTGACCTGGCACCGTCTAACCTGACCCTGTGGTCTGGTTCTAAAGCAATCAACGAAGATGCT
GCGGGTAACTACATCCACTACGGTGTTCGCGAGTTCGGTATGACCGCGATTGCTAACGGTATCTCCCTGCACGGTGGCTT
CCTGCCGTACACCTCCACCTTCCTGATGTTCGTAGAATACGCACGTAATGCCGTACGTATGGCTGCGCTGATGAAACAGC
GTCAGGTGATGGTTTACACCCACGACTCCATCGGTCTAGGCGAAGATGGCCCGACTCACCAGCCGGTAGAGCAGGTTGCT
TCTCTGCGCGTGACCCCGAACATGTCTACATGGCGTCCATGTGACCAGGTTGAATCTGCAGTGGCATGGAAATACGGTGT
TGAGCGTCAGGACGGCCCGACCGCGCTGATCCTCTCCCGTCAGAACCTGGCGCAGCAGGAGCGTACTGAAGAGCAGCTGG
CAAACATCGCGCGCGGTGGTTATGTGCTGAAAGACTGTGCCAGTCAGCCGGAACTGATCTTCATCGCGACCGGTTCGGAA
GTTGAACTGGCTGTTGCCGCCTACGAAAAACTGACTGCCGAAGGCGTGAAGGCGCGCGTGGTTTCCATGCCGTCTACCGA
CGCATTCGACAAGCAGGACGCGGCTTACCGTGAGTCTGTACTGCCGAAAGCGGTTACTGCACGCGTTGCGGTAGAAGCGG
GTATTGCTGACTACTGGTACAAGTATGTTGGCCTGAACGGCGCTATCGTCGGCATGACCACCTTCGGTGAATCTGCTCCG
GCAGAGCAACTGTTCGAAGAGTTCGGTTTCACCGTTGACAACGTCGTTGCGAAAGCAAAAGAACTGCTGTAA

Protein sequence :
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAGQAKEAAWNEKFAAYAKAFPQ
EAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDA
AGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVA
SLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCASQPELIFIATGSE
VELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVGLNGAIVGMTTFGESAP
AEQLFEEFGFTVDNVVAKAKELL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 83
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 69