Gene Information

Name : lysS (Synpcc7942_2415)
Accession : YP_401432.1
Strain : Synechococcus elongatus PCC 7942
Genome accession: NC_007604
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2486856 - 2488370 bp
Length : 1515 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGATTTGCGCGCCACCCGCCTCGAAAAAGCCCTGCAATTGCGAGAGCTGGGATTTGAGCCCTACGCCTACCGTTG
GGACTGTAGCCATAGTGCCGCGCAGCTCCAAGCGCTCTATGCTGACTTGCCAGCCGGGGAGGAAGTGGCGGTTGAGGTCG
CGATCGCGGGCCGAATTATGGCGCGGCGCGTCTTCGGGAAGCTGGCCTTCTTCACGCTGCAGGATGAAAGCGGCCAAATT
CAGCTCTACCTCGAGAAGCAGCGGCTCAGTGAATCGATGGCCGCGATCGATGCCGAAGCTTTCAGTCACCTCAAAGCCCT
GACAGATGTGGGCGACATTCTTGGTGTCAAAGGTAGTGTGCGCCGCACGGAGAAAGGCGAACTCTCGATCGCAGTGGATC
AGTACGCCATTCTCACTAAGTCCCTGCAACCCCTGCCGGATAAATGGCATGGACTGACGGATGTGGAGAAGCGCTACCGC
CAGCGCTACGTGGACCTGATCGTCAACCCAGAAGTACGGGAGACGTTTCGGCGTCGCGCCAAAATCACCGCTGCCATTCG
TCGCCACCTCGAAGATCAGGGCTTCATCGAAATCGAAACGCCAGTGCTGCAAGCGGAGGCAGGCGGTGCAGAAGCTCGGC
CTTTCATCACTTACCACAACACCTTAGAACTCGACCTTTATCTGCGAATTGCAACCGAGTTGCACCTCAAGCGCCTAATT
GTCGGCGGCTTCGAGAAAGTGTTTGAACTAGGGCGCATTTTCCGCAACGAGGGCATTTCAACCCGCCACAACCCTGAGTT
CACCTCGATCGAGGTCTATCAGGCCTATGCCGACTACGAAGACATGATGCGGCTAACGGAAACCTTGATTGCCCAAGTTG
CTGAGCAGGTGGTGGGGTCGCTGCAAGTGCCCTACCAAGGTCAGACGATCGATCTGGCGCCACCGTGGAAACGGGCAACG
ATGGCGGAACTGGTGTTGGCAGCGACGGGGATCGACTTCGAGTCCCTGAAAGACCTAGAAGCAGGAATTGCAGCCGTGAA
AGCAGCAGGTATTCCGGTGCCTGAGGACTGCCCCAACCTCGGCAAACTGCTCAACCACTGCTTCGAAGAAAAAGTGGAAG
CAACGCTGATTCAGCCGACGTTTGTGATCGACTATCCGGTGGAGATTTCGCCGCTGGCGAAGCCGCACCGCAGCAAACCA
GGGTTAGTGGAACGCTTTGAGCTATTTATTGTCGGCCGAGAAACTGCTAACAGCTTCTCGGAGTTAACCGATCCGGTGGA
TCAGCGACAACGGTTGGAAGCGCAAGCGGCAGACAAAGCAGCAGGCAATGTCGAAGCGAACGACGTCGACGAAGACTTCT
TGCTGGCGCTGGAGCATGGCATGCCACCGACCGGTGGCCTCGGAATTGGCATCGATCGCCTCGTGATGTTGCTGACCGAT
AGCCCCAGCATCCGTGACGTGATTGCCTTCCCACTGCTACGCCCCGAAGCGAGCTCGGAAGAGGCCGAAGCCTAA

Protein sequence :
MSDLRATRLEKALQLRELGFEPYAYRWDCSHSAAQLQALYADLPAGEEVAVEVAIAGRIMARRVFGKLAFFTLQDESGQI
QLYLEKQRLSESMAAIDAEAFSHLKALTDVGDILGVKGSVRRTEKGELSIAVDQYAILTKSLQPLPDKWHGLTDVEKRYR
QRYVDLIVNPEVRETFRRRAKITAAIRRHLEDQGFIEIETPVLQAEAGGAEARPFITYHNTLELDLYLRIATELHLKRLI
VGGFEKVFELGRIFRNEGISTRHNPEFTSIEVYQAYADYEDMMRLTETLIAQVAEQVVGSLQVPYQGQTIDLAPPWKRAT
MAELVLAATGIDFESLKDLEAGIAAVKAAGIPVPEDCPNLGKLLNHCFEEKVEATLIQPTFVIDYPVEISPLAKPHRSKP
GLVERFELFIVGRETANSFSELTDPVDQRQRLEAQAADKAAGNVEANDVDEDFLLALEHGMPPTGGLGIGIDRLVMLLTD
SPSIRDVIAFPLLRPEASSEEAEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-99 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 7e-78 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_401432.1 lysyl-tRNA synthetase VFG1668 Protein 1e-99 48