Gene Information

Name : guaA (Synpcc7942_0189)
Accession : YP_399208.1
Strain : Synechococcus elongatus PCC 7942
Genome accession: NC_007604
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 187531 - 189258 bp
Length : 1728 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGGGGGAATCTTCAGCCCGGAAACCGAATATCAGCGTCAGCGGACGATGGCTTGTTCACCCCGCGATCGCGGCCTTCAG
TTCTGCGTTTCCCGGTTGTTTTTGCCCCTTGCCGAGCCCTGCCGTGACGCTCCAGACTGAAATGGAGGCTGCACTTGAAG
TTGCAGCCTTGAACCGTGAAATGTTGATCATTCTGGACTTCGGGTCGCAGTACTCGGAGCTGATTGCTCGCCGCATTCGC
GAAACGCAAGTTTATTCAGAAGTGCTGTCCTACCGCACCACGGCGGATCAAATTCGGCAGCTGTCTCCCAAGGGCATCAT
CCTTTCAGGCGGCCCTAATTCGGTCTACGACGACTACGCGCCAGTTTGCGATCCAGAAATCTGGAATCTGGGAATTCCGG
TGCTGGGCGTCTGCTACGGCATGCAGCTGATGGTGCAACAGCTAGGGGGCCAAGTCGATCGCGCCGAGCGTGGCGAATAT
GGCAAGGCAGCGTTGGTCATCGACGATCCGACCGATTTGCTGACCAACGTCGAACCGGGCTCGACCATGTGGATGAGCCA
TGGCGACTCTGTCAAAACCATGCCCGAGGGCTTTGAGCTGCTCGCCCACACCGATAACACCCCCTGCGCTGCGATCGCGG
ATCACCAGCGCAAGTTCTACGGCGTGCAGTTCCACCCGGAAGTCGTGCATTCCGTGCATGGCATGGCGCTGATTCGCAAC
TTTGTCTATCACATTTGCGATTGCGAACCGACTTGGACAACGGAAACCTTTGTCGAAGAAGCGATTCGCGAAATTCGGGC
ACGAGTCGGTGATAAGCGCGTTCTCCTAGCGCTATCCGGCGGTGTAGATTCTTCGACGCTGGCCTTCCTGTTACATCGGG
CAATCGGCGATCAGCTGACCTGTATGTTCATTGATCAGGGCTTCATGCGCAAAGGCGAACCGGAGCGCTTGATGGAGGTA
TTCAACGAGAAATTCAAGATTCATGTTGAATATATTCAAGCTCGCGATCGCTTCTTACAGCGACTGGAAGGCATCACCGA
TCCCGAAGAAAAACGCAAACGGATTGGCCACGAATTCATTCGCGTTTTTGAAGAAGAATCGCGTCGGCTCGGCCCCTTCG
ACTATCTGGCCCAAGGCACGCTCTATCCCGATGTGATTGAGTCGGCAGACACTAACGTCGATCCCAAAACGGGCGAGCGA
GTGGCGGTCAAGATCAAGAGCCACCACAACGTCGGTGGTCTGCCCAAAGACCTCCAGTTCAAGCTAGTTGAACCGCTGCG
GCGTCTGTTCAAAGATGAAGTGCGTCAGGTTGGGCGATCGCTGGGTCTACCAGAAGAAATCGTCAAGCGCCATCCGTTCC
CAGGCCCGGGCCTCGCGATTCGGATTCTGGGTGAAGTCACAGCTGAAAAGCTCAACATCCTGCGCGATGCAGACTTGATT
GTTCGCCAGGAAGTCAACCGTCAGGGCTATTACGACGAGTTCTGGCAAGCCTTCGCTGTGCTGCTGCCGGTCAAGAGTGT
CGGTGTGATGGGCGACAAGCGCACCTACGCCTACCCTGTTGTGCTGCGTTTTGTCAGCAGTGAAGACGGCATGACCGCTG
ACTGGTCGCGGGCTCCCTACGACCTACTGGAGACGATTTCGAATCGGATTGTCAACGAAGTGAAAGGCGTCAACCGCGTC
GTCTACGACATCACCTCGAAACCCCCTGGCACGATCGAGTGGGAATGA

Protein sequence :
MGESSARKPNISVSGRWLVHPAIAAFSSAFPGCFCPLPSPAVTLQTEMEAALEVAALNREMLIILDFGSQYSELIARRIR
ETQVYSEVLSYRTTADQIRQLSPKGIILSGGPNSVYDDYAPVCDPEIWNLGIPVLGVCYGMQLMVQQLGGQVDRAERGEY
GKAALVIDDPTDLLTNVEPGSTMWMSHGDSVKTMPEGFELLAHTDNTPCAAIADHQRKFYGVQFHPEVVHSVHGMALIRN
FVYHICDCEPTWTTETFVEEAIREIRARVGDKRVLLALSGGVDSSTLAFLLHRAIGDQLTCMFIDQGFMRKGEPERLMEV
FNEKFKIHVEYIQARDRFLQRLEGITDPEEKRKRIGHEFIRVFEEESRRLGPFDYLAQGTLYPDVIESADTNVDPKTGER
VAVKIKSHHNVGGLPKDLQFKLVEPLRRLFKDEVRQVGRSLGLPEEIVKRHPFPGPGLAIRILGEVTAEKLNILRDADLI
VRQEVNRQGYYDEFWQAFAVLLPVKSVGVMGDKRTYAYPVVLRFVSSEDGMTADWSRAPYDLLETISNRIVNEVKGVNRV
VYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-139 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-127 52