Gene Information

Name : guaA (PMT9312_0037)
Accession : YP_396534.1
Strain : Prochlorococcus marinus MIT 9312
Genome accession: NC_007577
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 34810 - 36396 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGTCAAACATCTTTAAAAAAAGAACGCGATCCTTCAATACTAATTTTAGATTTCGGATCTCAATATTCTGAATTGAT
TGCAAGAAGAATTAGAGAAACTAATGTTTTTTCTCTTGTAGTAAGTAACTGTATTTCAATTGAAGAAATTAATGATATTA
ATCCTAAAGGGATAATTTTGAGTGGCGGTCCAAATTCTGTATATGAAAAAAATGCTCCAAAATGTGATGAAAAAATTTTT
AATTTAGGAATTCCTATTCTTGGCATATGCTATGGAATGCAATTAATGGTCAAAGAACTTGGTGGATCTGTAACTTCAGC
AACCAAAAAAGCAGAATATGGTAGAGCACCAATAAATATAGATCAAGAATCTGAACTCCTTTCTGATGTAGAAGATAAAT
CCATAATGTGGATGAGTCATGGCGATTCAATTAATTGTTTGCCTGATGGATTTAATAAAATTGCTCATACCGAGAACACA
CTCCATGCAGCAATTTCAAATGATAGAAAGAAATTATTTGGCGTACAATTTCATCCTGAAGTAATTCATTCAGAGTTTGG
GATAACGGTAATTAAAAATTTTGTTTATGGCATTTCTAGTTGTGTGGCTGATTGGACAACCGAAACCTATATAGAGGAAA
CTATTCCTAGGATAAGAGATCAAGTTGGCAATAAAAAAGTTTTGCTTGCTTTGTCAGGAGGAGTTGATTCGTCAACTCTT
GCGTTTCTTCTCAATAAAGCAATTGGAAATCAGCTTACATGCATGTTTATAGACCAAGGTTTTATGAGAAAAGGTGAACC
TGAATTTTTAATGAATTTTTTTGATAAGAAATTTCATATAAAGGTTGAATATATTAATGCAAGGGAAAGGTTTATTTCCA
AATTAAAAGGGATTACTGATCCAGAACAAAAAAGGAAAATTATTGGTGAAGAATTTATTAGAGTATTTGAAGAAGAAAGT
AATAGATTGGGCCCTTTTCAGTATTTAGCCCAAGGTACTCTTTATCCTGATGTTATTGAAAGTGCTGGTACTAATATTGA
TCCAAAGACTGGGGAAAGAATAGCTGTAAAAATTAAGAGTCATCATAATGTGGGGGGATTACCAAAAGATTTACAATTTA
AATTAGTTGAGCCATTAAGAAAACTTTTTAAGGATGAAGTCCGCAAATTGGGAGCTGCCTTAGGTTTGCCGGATGAAATT
ATAAAAAGGCATCCATTCCCGGGACCAGGTTTAGCGATAAGAATTTTGGGAGAAGTTAATAATGAAAAACTTGACTGTTT
AAGAGATGCAGATTGGATAGTGCGAGACGAAATTAAAAAAGCAGGTCTTTACAATGATATTTGGCAAGCTTTCGCAGTAT
TGCTACCAGTTAAAACTGTAGGAGTTATGGGTGATAAAAGGACTTATGCATGGCCAATAGTTTTACGTTGTGTATCTAGT
GAAGATGGTATGACAGCAGACTGGTCAAAAATTCCTTTTCCGATTTTAGAGAGAATTTCTAATAGAATCGTAAATGAAGT
AGTTTCAGTTAATAGAGTGGTTTATGATATTACAAGCAAACCTCCAGGAACTATTGAGTGGGAGTGA

Protein sequence :
MSQTSLKKERDPSILILDFGSQYSELIARRIRETNVFSLVVSNCISIEEINDINPKGIILSGGPNSVYEKNAPKCDEKIF
NLGIPILGICYGMQLMVKELGGSVTSATKKAEYGRAPINIDQESELLSDVEDKSIMWMSHGDSINCLPDGFNKIAHTENT
LHAAISNDRKKLFGVQFHPEVIHSEFGITVIKNFVYGISSCVADWTTETYIEETIPRIRDQVGNKKVLLALSGGVDSSTL
AFLLNKAIGNQLTCMFIDQGFMRKGEPEFLMNFFDKKFHIKVEYINARERFISKLKGITDPEQKRKIIGEEFIRVFEEES
NRLGPFQYLAQGTLYPDVIESAGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRKLGAALGLPDEI
IKRHPFPGPGLAIRILGEVNNEKLDCLRDADWIVRDEIKKAGLYNDIWQAFAVLLPVKTVGVMGDKRTYAWPIVLRCVSS
EDGMTADWSKIPFPILERISNRIVNEVVSVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-134 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-134 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-134 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-122 50