Gene Information

Name : lysS (PMT9312_1711)
Accession : YP_398208.1
Strain : Prochlorococcus marinus MIT 9312
Genome accession: NC_007577
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1599215 - 1600753 bp
Length : 1539 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTCTGAAATAAGAGAAGCACGCTTACAAAAAGCTAATTCACTAGTTAGTAAAGGATTTGCTTCTTACGCAGAGAGTTT
TAGCGTTTCACATACTACAAAATTTCTTATTCAAAAATTTGATTATTTAGAAAATGGTCAAGAGGAAGACTTCAGTGTTT
CTCTCGCTGGTAGAGTGATGGCAAAAAGGGTAATGGGTAAAATTGCTTTTTTCACAATAAGCGATCAAGAAGGACAGATT
CAGCTTTATCTAGATAAAAGGATGATTAATTGCAATTTAGAAAACCAAAAATTACTTTCTTTTGAAGATATTAAGGAAAT
AGTAGATATTGGTGATTGGATAGGCGTATACGGCACTATTAAAAAGACTAATAAAGGGGAGCTTTCAATTAAAGTAGAAA
AATGGGAAATGTTATCCAAATCATTACAGCCTTTACCCGATAAATGGCATGGATTGACTGATATTGAAAAAAGATATAGA
CAACGTTATCTAGATTTAATAGTTAATCCACACTCTAAAAATGTATTTAAAACAAGAGCAAAATGTATAAGTTTTATAAG
ACAATGGCTAGATAATAGAAATTTTTTAGAGATAGAGACTCCAATTCTTCAATCTGAAGCTGGTGGTGCTGAAGCAAGAC
CATTTATTACTCATCACAATACATTGGATATTCCGCTGTATCTAAGAATAGCTACAGAATTACATTTAAAAAGAATGGTT
GTTGGAGGATTTGAGAAAGTTTATGAATTGGGAAGAATCTTCCGTAATGAGGGGATAAGTACAAAGCATAATCCAGAATT
TACCTCAGTTGAAATTTATCAAGCTTTTTCTAACTATGTCGATATGATGAATCTAACAGAAGAACTGATTAAAGATATTG
TATTTAATGTGTGTGGTTCTTTAGTTATAAATTATCAAAATAAGGAAATTGATTTTTCTAAACCTTGGTCAAGAATATCC
ATGAAAGATATTGTCAAAAAATATACAGGGATTGATTTTGATTCTTTCAGTGGAGACTTTCAATCAGCAAAACAAGCCGT
TAAAAGTATAAATGTTGAATTTTCTAATAAAGTGAATTCTATGGGAAGACTTTTAAATGAGGTCTTCGAGCAAAAAGTTG
AGTCAGAACTTATAGAACCTACTTTTGTTATCGATTATCCTGTTGAAATTTCTCCTTTAGCTAGGCCTCATCTTGATAAT
AAAGAAATGGTTCAGAGATTCGAATTATTTATTGTTGGACGAGAGCTAGCAAATGCGTTTAGTGAGTTGATAGATCCAGT
AGATCAAAGAGAAAGAATGCAATTACAGCAATCTCTTAGAGATGAAGGAGATCATGAGGCTCATTGTATAGATGAAGATT
TTTTGAATGCTTTGGAGATTGGTATGCCTCCTACTGGGGGATTAGGCATAGGTATTGATAGACTGATTATGCTAATTACT
AATAGTCCATCAATTAGAGATGTAATCCCTTTCCCATTGTTAAAACCAGAAATAACTTCCAATAAAAACGAAAAATTACC
CTTGAATGAAGTAAAATAA

Protein sequence :
MSEIREARLQKANSLVSKGFASYAESFSVSHTTKFLIQKFDYLENGQEEDFSVSLAGRVMAKRVMGKIAFFTISDQEGQI
QLYLDKRMINCNLENQKLLSFEDIKEIVDIGDWIGVYGTIKKTNKGELSIKVEKWEMLSKSLQPLPDKWHGLTDIEKRYR
QRYLDLIVNPHSKNVFKTRAKCISFIRQWLDNRNFLEIETPILQSEAGGAEARPFITHHNTLDIPLYLRIATELHLKRMV
VGGFEKVYELGRIFRNEGISTKHNPEFTSVEIYQAFSNYVDMMNLTEELIKDIVFNVCGSLVINYQNKEIDFSKPWSRIS
MKDIVKKYTGIDFDSFSGDFQSAKQAVKSINVEFSNKVNSMGRLLNEVFEQKVESELIEPTFVIDYPVEISPLARPHLDN
KEMVQRFELFIVGRELANAFSELIDPVDQRERMQLQQSLRDEGDHEAHCIDEDFLNALEIGMPPTGGLGIGIDRLIMLIT
NSPSIRDVIPFPLLKPEITSNKNEKLPLNEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-101 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_398208.1 lysyl-tRNA synthetase VFG1668 Protein 1e-101 46