Gene Information

Name : panE (LSA0041)
Accession : YP_394653.1
Strain : Lactobacillus sakei 23K
Genome accession: NC_007576
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 38535 - 39473 bp
Length : 939 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGACAAAAATTGCAATTGCCGGTTCTGGTGCAATGGGCAGCCGTTTTGGCTACATGCTACAAGCAGCCGGGAACGATGT
CGTCTTACTAGACAATTGGGTCGAACATGTTCAGGCAATTAATACCAAGGGTTTAACGGTAGCGATTGCGGGACAAGACG
TGCAACACGTTCAAATTCCAGCAGCCTTACCCACAGCGATTAAAGACGTTCAAGATGTGATTATCATCTTCACGAAATCG
ATGCAATTAGGGGCGATGCTACAATCGATTAAACCGCTGATTGGTGAGAAGACGAAGGTCGTTTGTTTATTAAATGGCTT
GGGTCATCCCGAAACAATTGAACGCTACTTACCCAAACATAATATCTTCGTCGGCATTACGTTGTGGACTGCTGGTTTAA
CCGGTCCTGGGGAAATTAGCCTTAGTGGTTCCGGCAGTGTTGAACTTCAAAACGTGGCCCCAGAAGCCAAAGGTGCCGCT
GAAGAATTAGTCGCGATGTTGAGTGCCGCTGGTTTACATGCGACCTATAGTGCTGATGTCTTGTTTTCAATTTGGCGCAA
AGCTTGTGTGAATGGCACCTTGAATAGCCTCTGTGCTTTATTGGATTGTAACATTGCCCAACTCGGTCGGACGAGTCAGG
TCAACTCATTACTGGCTTCGATTGTGGCTGAATTTTCAGCAGTGGCAGCGACCGAAGCGGTTGATTTGGATGTGCCAACA
ACGATTGCGCATATCGATCAATTATTTGATCCCACCCAAGCTGGCGAACATTATCCATCGATGCACCAAGATTTAATCCA
ACACCATCGTTTAACGGAAATTGATTACTTAAACGGCTACGTTGCGCGCAAAGGCCAAGAACGTGGCATTCCAACGCCCG
TCAACCAATTGATTACCCAACTTGTGCATACTAAAGAAGCACTCGTCATCGAAAAATAA

Protein sequence :
MTKIAIAGSGAMGSRFGYMLQAAGNDVVLLDNWVEHVQAINTKGLTVAIAGQDVQHVQIPAALPTAIKDVQDVIIIFTKS
MQLGAMLQSIKPLIGEKTKVVCLLNGLGHPETIERYLPKHNIFVGITLWTAGLTGPGEISLSGSGSVELQNVAPEAKGAA
EELVAMLSAAGLHATYSADVLFSIWRKACVNGTLNSLCALLDCNIAQLGRTSQVNSLLASIVAEFSAVAATEAVDLDVPT
TIAHIDQLFDPTQAGEHYPSMHQDLIQHHRLTEIDYLNGYVARKGQERGIPTPVNQLITQLVHTKEALVIEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 9e-82 53
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 7e-82 53