Gene Information

Name : serS (LSA1803)
Accession : YP_396416.1
Strain : Lactobacillus sakei 23K
Genome accession: NC_007576
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1792494 - 1793768 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATCAGAGTAATTCGGGAAAATGTCCAATGGGCAAAGGATAAATTAGCGACTCGCGGCATTGATGCTGCAGA
AATCGACGAGGTAGTTGCCTTAGATGAAAAACGCCGCGCTTTAATCGTCCGCACAGAAGAATTGAAGAAAAATAGAAACG
CTGCTTCAGAAGCAATCGCTGTTGCTAAACGCAATAAGGAAGATGCAACTGAACAAATCGCTGCTATGAAGAACGTCGGT
GCAGAAATTAAAGAATTAGATGCACAATTAGCTGAAGTGAAGGAAAAAGTAGACTATATCTTGGTTCGCTTACCTAACTT
CCCTGATGATTCAGCACCAGTTGGTTTGGATGAAAGCTTCAGCCGTGAAGAACGTAAATGGTCAACACCACGTGAATTTG
ATTTCGAACCATTAGCACACTGGGATATCGGTGAAAAACTTGGTATTTTAGATTTCGAACGTGCTGCTAAAGTTTCAGGC
AGCCGTTTCGTTTATTACAAGGGTGCTGGTGCACGTTTGGAACGGGCCGTTTATAACTTTATGTTAGATCAACATGCCAA
AGAAGGTTATGAAGAAATGATTACCCCTTACTTGGTTAATGGTGAATCAATGTTTGGAACTGGCCAATTTCCTAAGTTTA
CGGAAGATGTTTACACAATGACTAACGAAGGCGAACCAATGACCTTGATTCCAACTGCCGAAGTGCCATTGACAAACTTC
TACCGTGATGAAATCTTAGATGGTGCACAATTGCCAATCTACTTCACAGCCTTATCACCAGCCTTCCGTTCAGAAGCTGG
GAGTGCCGGCCGTGATACGCGTGGTTTAATCCGGATGCACCAATTTAACAAAGTTGAAATGGTGAAATTCACAAAACCTG
AAGAATCATTCAACGAATTAGAAAAAATGACCGCCGATGCTGAAAATATCTTAAAAGCATTGAACTTGCCATACCACGTT
ATCACATTGGCAACTGGCGATGCCAGCTTCACATCAGCTAAGACTTATGATATTGAAGTTTGGTTACCCGCTCAAAATAC
GTACCGCGAAATCTCAAGCTGTTCAGATTGTACAGACTTCCAAGCACGCCGCGCCCAAATTCGTTACCGTGACGAAGATG
GCCACGTCAACTTGGTCCACACATTGAACGGTTCAGGCCTAGCAGTTGGCCGGACAGTTGCAGCTATTTTGGAAAACTAT
CAAAATGAAGACGGTACTGTTACAATCCCAGAACCATTAGTACCATACATGGGCGGTATGACAAAAATTGGCTAG

Protein sequence :
MLDIRVIRENVQWAKDKLATRGIDAAEIDEVVALDEKRRALIVRTEELKKNRNAASEAIAVAKRNKEDATEQIAAMKNVG
AEIKELDAQLAEVKEKVDYILVRLPNFPDDSAPVGLDESFSREERKWSTPREFDFEPLAHWDIGEKLGILDFERAAKVSG
SRFVYYKGAGARLERAVYNFMLDQHAKEGYEEMITPYLVNGESMFGTGQFPKFTEDVYTMTNEGEPMTLIPTAEVPLTNF
YRDEILDGAQLPIYFTALSPAFRSEAGSAGRDTRGLIRMHQFNKVEMVKFTKPEESFNELEKMTADAENILKALNLPYHV
ITLATGDASFTSAKTYDIEVWLPAQNTYREISSCSDCTDFQARRAQIRYRDEDGHVNLVHTLNGSGLAVGRTVAAILENY
QNEDGTVTIPEPLVPYMGGMTKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-142 69