Gene Information

Name : lysS (LSA1594)
Accession : YP_396207.1
Strain : Lactobacillus sakei 23K
Genome accession: NC_007576
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1577615 - 1579132 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGGCACAAAAAGATAATCAAAAAGAAATGAATGACCAACTTAAGGTCCGTCGCGAAAAAATGCAATTTTTAAAGGATGA
AGGCATTGATCCTTTTGGGAGCCGTTTTGAACGGACGCATTTAGCAGCAGCGCTACACGAAGAATTTGAAGCAATTGAAA
AAGACGACTTGGATGTTAAAAACCAAGAAGTCACAATTGCAGGACGAATGATGTCTAAACGGGGTAAAGGTAAAGTTGGT
TTTGCCGATATCCGTGATCGTTCTGGTAAAATTCAAATTTATGTTCGTAAAGACGAAGTCGGTGAAGATAACTACAAAAT
TTTCAAGAAAGCCGATTTAGGGGATCACTTAGGCATTACCGGTCAAATCATGAAAACTGATATGGGTGAGTTAACGGTTA
AGGCAACTCATCTAACATTCTTGTCAAAGGCATTACGCCCATTACCTGATAAGTATCACGGTTTAACGAATGTCGAACAA
ATTTATCGTCAACGTTATTTAGATTTGATTGCTAATCCTGAAAGTATGGATCGTTTCACGAAGCGGAGCAAGATTATTTC
TGCTGTTCGTGAATATTTAGATACACATGACTTTACTGAAGTTGAAACACCTGTCTTGCATGGTCAAGCTGGTGGGGCTT
CAGCACGGCCATTTATTACACATCACAATGCATTAGACATTAACCTCTATTTACGAATTGCGCTTGAATTACACTTGAAG
CGACTAATCGTTGGTGGGATGGAACGGGTCTATGAAATTGGCCGTGTATTCCGGAATGAAGGTATTGATACCAAACATAA
CCCTGAATTCACGATGTTAGAAACATACGCTGCATACTTTGATTACAAAGATGTCATGGATGAAACCGAAGGCATTATCC
GTTTTGCAGCTCATAAAGTCTTGGGAACTGGTCAAATTTCATACCAAGGCCAAGCAATTGATTTAGATAGTGATTTTGCC
CGTGTACACATGGTCGACGCTATTAAGGCTGAAACAGGTGTCGATTTCTGGCAACCAATGACAGTTGAATCTGCTCGTGA
ATTAGCAGACCAACACCACGTTAAGTATGAAGAATACTGGCAAGTGGGTCATATCATTAACGCCTTCTTTGAAGAATTCG
TTGAAGATACATTAGTACAACCAACATTCATTTATGGCCATCCAGTGGAAATTTCACCATTGGCTAAGAAGAATGCCGAA
GACGATCGTTTTACAGATCGTTGGGAACTCTTCATGCATGGTAACGAATATGCAAATGCCTTTACTGAATTGAATGATCC
AATCGATCAACGTGAACGTTTTGAAGCACAAGCTAAGGAACGTGAAAATGGTAATGATGAAGCTGAAGGTATCGATGAAG
ATTATGTCGAAGCATTAGAATACGGGATGCCGCCTACAGGTGGACTCGGTATTGGGATTGACCGGCTTGTTATGTTATTA
ACTGACGCTGCTTCGATCCGCGATGTCCTTTTATTCCCAACAATGCGTCCAGACAAGCAAGAAAATGAAGAAATTTAA

Protein sequence :
MAQKDNQKEMNDQLKVRREKMQFLKDEGIDPFGSRFERTHLAAALHEEFEAIEKDDLDVKNQEVTIAGRMMSKRGKGKVG
FADIRDRSGKIQIYVRKDEVGEDNYKIFKKADLGDHLGITGQIMKTDMGELTVKATHLTFLSKALRPLPDKYHGLTNVEQ
IYRQRYLDLIANPESMDRFTKRSKIISAVREYLDTHDFTEVETPVLHGQAGGASARPFITHHNALDINLYLRIALELHLK
RLIVGGMERVYEIGRVFRNEGIDTKHNPEFTMLETYAAYFDYKDVMDETEGIIRFAAHKVLGTGQISYQGQAIDLDSDFA
RVHMVDAIKAETGVDFWQPMTVESARELADQHHVKYEEYWQVGHIINAFFEEFVEDTLVQPTFIYGHPVEISPLAKKNAE
DDRFTDRWELFMHGNEYANAFTELNDPIDQRERFEAQAKERENGNDEAEGIDEDYVEALEYGMPPTGGLGIGIDRLVMLL
TDAASIRDVLLFPTMRPDKQENEEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-109 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_396207.1 lysyl-tRNA synthetase VFG1668 Protein 1e-109 48