Gene Information

Name : leuS (LSA1436)
Accession : YP_396045.1
Strain : Lactobacillus sakei 23K
Genome accession: NC_007576
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1408408 - 1410831 bp
Length : 2424 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTTACGATCATCGCGCAGTTGAACAAAAGTGGCAAGCCTACTGGCAATCACATAAATCTTTTAAAACAACAGAAGA
TAAAGATAAGAAAAATTTCTACGCATTAGATATGTTCCCATATCCATCAGGACAAGGGTTGCACGTTGGCCATCCTGAAG
GCTATACGGCAACTGATATCTTGGCCCGGATGAAACGGATGCAAGGCTTCAACGTGTTGCACCCAATGGGTTGGGATGCA
TTCGGCTTACCTGCTGAACAATATGCGTTAGATACGGGGAATAACCCTGCTGATTTCACGCAAAAAAATATCAACACTTT
CAAACGTCAAATCAATTCATTAGGCTTCTCATACGATTGGGATCGCGAAGTGAATACAACGGATCCTGATTTCTACAAAT
GGACCCAATGGATTTTTGAAAAAATGTACGAAAAAGGCTTGGCTTATGAAGCCGAAGTTGCTGTTAACTGGAGCCCAGAT
TTAGGGACAGTTGTGGCCAACGAAGAAGTGATCGACGGTAAAACTGAACGTGGTGGTTACCCTGTTTACCGGAAACCAAT
GCGTCAATGGATGTTGAAGATTACGGCTTATGCTGATCGTTTAATTGACGACTTAGACCTTGTTGATTGGCCTGAAAGTG
TCAAGGATATGCAACGTAACTGGATTGGCCGCTCAAAAGGCGCTGAAGTTTCATTTGCTGTTGAAAACCATGACGCTAAT
ATTGACGTCTTCACAACACGTGCCGACACAATGTTTGGTGTGAGTTACATCGTGATGGCGCCAGAACACAAATTAGTAGC
TGACATCACAACGCCTGAACAAAAAGCTGCCGTTGATGCATACTTAAAAGAAATCGAACACAAGAGTGATCTTGAACGGA
CTGATTTGGCTAAGGACAAAACAGGTGCCTTTACGGGTGCTTATGCCATCAATCCAGTGAACGGCGAACGTTTACCAATC
TGGATTTCAGATTACGTTTTAGCTTCATACGGGACTGGTGCTGTCATGGCCGTTCCTGCACATGACCCTCGCGATTGGGA
ATTTGCCAAGAAATTCGGTTTACCATTGAAACCAGTTGTTTCAGGCGGTAACCCTGAAGAAGCTGTTCACACAGAACCTG
GTGTGATGATCAATTCAGATTTCTTAGATGGCTTAGACAAACAAGCTGCTATCGACAAGATGATTCCATGGTTGGTTGAA
CACAAAGTGGGTCATGAACAAATCAGTTATAAATTACGTGACTGGTTATTCTCACGTCAACGCTACTGGGGTGAACCAAT
TCCAATTATTCATTGGGAAGATGGCACAACATCTGTCGTTCCAGAAGATCAATTGCCACTTGAATTACCATTAACAAGCG
ATATCAAACCTTCTGGTACTGGTGAAAGTCCACTTGCGAACTTAACAGACTGGTTAAACGTGACGGACGAAAATGGTCGT
AAAGGCCGTCGTGAAACGAATACAATGCCACAATGGGCTGGTAGTTCATGGTATTACCTCCGTTATATCGATCCTAAGAA
CCCTGATAAATTGGCTGATTTTGACAAGTTGAAGGACTGGTTACCAGTTGACATGTACATCGGTGGTGCAGAACATGCTG
TTCTTCATTTACTATATGTTCGTTTCTGGCACAAATTCTTGTATGATATCGGTGTCGTCCCAACGAAGGAACCATTCCAA
CACCTATACAATCAAGGGATGATTTTAGGCGATAACCACGAAAAAATGTCTAAATCAAAAGGGAACGTTGTTAACCCTGA
TGATGTTGTTGATCGTTTTGGTGCTGATACATTACGTCTATACGAAATGTTCATGGGCCCATTAGATGCTTCAATTTCAT
GGAGTGAAAAGGGCTTAGCCGGCGCTCGTAAATTCTTGGACCGTGTATGGCGTTTATACACAGAAGAAGATACGGACGAA
AACGACCAACTTTCAAGCAAGATTGTCGCTGACAACAACGATCAATTGAAGAAGGTTTATAACGAAACTGTTAAGAAAGT
GACAGAAGACTTCGAAAGCATGCACTTTAACGTGGCCATTTCACAATTGATGGTCTTCATCAACGATGCTTATAAAGCAG
ATACATTCCCACGTGAATATGCTGAAGGCTTCGTGAAATTATTAGCCCCAATCGCACCACATATGATGGAAGAATTATGG
GCAATGCTTGGTCATGATGATTCAATCAGCTATGTTGATTGGCCAACATTTGACCCAGCAGCATTAATCGCTAATGAAGT
AGAAGTTATCTTCCAAGTTAACGGTAAGTTAAAGGCCAAAGTAACAGTGGCGAAAGATACACCGAAGGAAGAATTAGAAG
CGATGGCAAAGGCCAACGAAAAAGTAGCCGAATTTATCGCAGACAAGACAGTCCGTAAAGTGATTGCCATTCCAAACAAA
TTGGTAAACATTGTAGCGAATTAG

Protein sequence :
MTYDHRAVEQKWQAYWQSHKSFKTTEDKDKKNFYALDMFPYPSGQGLHVGHPEGYTATDILARMKRMQGFNVLHPMGWDA
FGLPAEQYALDTGNNPADFTQKNINTFKRQINSLGFSYDWDREVNTTDPDFYKWTQWIFEKMYEKGLAYEAEVAVNWSPD
LGTVVANEEVIDGKTERGGYPVYRKPMRQWMLKITAYADRLIDDLDLVDWPESVKDMQRNWIGRSKGAEVSFAVENHDAN
IDVFTTRADTMFGVSYIVMAPEHKLVADITTPEQKAAVDAYLKEIEHKSDLERTDLAKDKTGAFTGAYAINPVNGERLPI
WISDYVLASYGTGAVMAVPAHDPRDWEFAKKFGLPLKPVVSGGNPEEAVHTEPGVMINSDFLDGLDKQAAIDKMIPWLVE
HKVGHEQISYKLRDWLFSRQRYWGEPIPIIHWEDGTTSVVPEDQLPLELPLTSDIKPSGTGESPLANLTDWLNVTDENGR
KGRRETNTMPQWAGSSWYYLRYIDPKNPDKLADFDKLKDWLPVDMYIGGAEHAVLHLLYVRFWHKFLYDIGVVPTKEPFQ
HLYNQGMILGDNHEKMSKSKGNVVNPDDVVDRFGADTLRLYEMFMGPLDASISWSEKGLAGARKFLDRVWRLYTEEDTDE
NDQLSSKIVADNNDQLKKVYNETVKKVTEDFESMHFNVAISQLMVFINDAYKADTFPREYAEGFVKLLAPIAPHMMEELW
AMLGHDDSISYVDWPTFDPAALIANEVEVIFQVNGKLKAKVTVAKDTPKEELEAMAKANEKVAEFIADKTVRKVIAIPNK
LVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 67