Gene Information

Name : guaA (Suden_0422)
Accession : YP_392938.1
Strain : Sulfurimonas denitrificans ATCC 33889
Genome accession: NC_007575
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 422554 - 424104 bp
Length : 1551 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAAATGTTAGCATTATAGTATTGGACTTTGGCTCTCAATATACACAGCTTATAGCTCGCCGTCTTAGAGAAGATAA
AATTTATTGTGAAATTCTTCCATATCACACAAAAGTAGCAGATATTAAAGCAAAAAATCCACAAGGTATTATTTTAAGCG
GTGGTCCATCTTCAGTTTACAATAAAGATGCTTACGAGGTTGACCAAGGCGTTTATAAGATGGATATTCCAGTTCTTGGA
ATCTGTTATGGTATGCAAAGAATTGCAGCTGACTTTGGTGGAAGTGTTGTCCGTGCATCTCATCATGAATATGGCAAAGC
GGAACTAAAAATATTAAATCTAGAAACAAACCCTTCACCACTTTTTAAAGATTGTGATGATGAGAGAATTGTATGGATGA
GCCACAGTGATAAGGTAGATACCCTTCCTGCGGGCTTTGAACCAATTGCAGTCTCTTCTAACTCTCCATACGCTGCAATA
GCAAATGAAGAAAAACGCATCTACGCAATGCAGTATCATCCTGAAGTTCAACACTCAGAAGAGGGCTATTTGATGCTTCG
TAACTTTGCAAGAAATATTTGTGGAGTTACTGAGAAGTGGAAGATGGAGCACTTCTTAAAAGAGCAGATTAAGAATATTC
GCGCAAAAGTCGGTAGTGGAAAAGTACTGTGTGGACTTAGCGGCGGAGTTGATAGTTCCGTTGTAGCAGCTATGCTTTAT
GAGGCAATAGGAGATCAACTAGTACCTGTTTTTGTAGATAATGGGCTTCTTAGAAAAGGTGAGAGAGAGCAAGTTGAAGA
GGTTTTTAAAATAAATCTTAAGGTGCCTCTTGTTGTAGTTGATGCAAGAGAGAATTTCTTAAGTAAACTAGCAGGTGTTA
GTGACCCTGAGAAAAAAAGAAAGATTATTGGGCATACATTCATAGAGGAGTTTGAAAAAGAGGCTAAAAAACATGATGGT
ATTAAGTTTTTAGCTCAAGGAACTCTCTATCCAGATGTTATTGAATCTATAAGCGTTAATGGACCATCTGAGGTTATAAA
ATCTCATCATAATGTTGGCGGATTGCCTGATTGGATGGATTTCGAATTAATAGAGCCACTAAGAGAACTTTTTAAAGATG
AGGTTCGTAAAATCGGACTAGAATTAGGACTTCCCGAATCCATGATAAACCGTCATCCATTCCCTGGTCCAGGACTTGCA
ATTCGTATCATGGGAGATGTAAATGAGGCTGATTTAACACTTCTTCGTGAAGCAGATGTTATTTTGCTAGATGAGCTAAA
AGCTAGTGGGTACTATGCAAAAACATGGCAAGCGTTTGTGGTTTTATTAAATGTAAAATCGGTTGGAGTTATGGGCGATA
ACCGCACTTATGATAATACTGTTTGTGTAAGAGTTGTTGAGGCAGTTGATGGAATGACTGCAACATTTGCTCATCTGCCT
CATGACTTACTAGAGAGAATTAGTAGAAGAATTATAAATGAAGTAGATGGAATTAACCGTGTGGTTTATGATATAAGCTC
AAAGCCGCCTGCTACAATAGAGTGGGAATAA

Protein sequence :
MTNVSIIVLDFGSQYTQLIARRLREDKIYCEILPYHTKVADIKAKNPQGIILSGGPSSVYNKDAYEVDQGVYKMDIPVLG
ICYGMQRIAADFGGSVVRASHHEYGKAELKILNLETNPSPLFKDCDDERIVWMSHSDKVDTLPAGFEPIAVSSNSPYAAI
ANEEKRIYAMQYHPEVQHSEEGYLMLRNFARNICGVTEKWKMEHFLKEQIKNIRAKVGSGKVLCGLSGGVDSSVVAAMLY
EAIGDQLVPVFVDNGLLRKGEREQVEEVFKINLKVPLVVVDARENFLSKLAGVSDPEKKRKIIGHTFIEEFEKEAKKHDG
IKFLAQGTLYPDVIESISVNGPSEVIKSHHNVGGLPDWMDFELIEPLRELFKDEVRKIGLELGLPESMINRHPFPGPGLA
IRIMGDVNEADLTLLREADVILLDELKASGYYAKTWQAFVVLLNVKSVGVMGDNRTYDNTVCVRVVEAVDGMTATFAHLP
HDLLERISRRIINEVDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-140 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-140 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-140 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-125 52