Gene Information

Name : tkt-2 (GBAA_3744)
Accession : YP_020383.1
Strain : Bacillus anthracis Ames Ancestor
Genome accession: NC_007530
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3443842 - 3445842 bp
Length : 2001 bp
Strand : -
Note : 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exp

DNA sequence :
ATGTCACATTCAATCGAACAACTTTCTATCAACACGATTCGCACATTATCCATCGATGCGATTGAAAAAGCAAACTCTGG
TCACCCAGGAATGCCAATGGGTGCAGCACCAATGGCTTATACATTATGGACTCAATTTATGAAACACAATCCAAATAACC
CAACGTGGTTTAACCGTGATCGTTTCGTATTATCTGCAGGTCATGGTTCAATGTTATTATACAGCCTACTTCACCTATCT
GGTTATGATGTAACAATGGATGACTTAAAGAACTTCCGTCAATGGGGAAGCAAAACTCCAGGGCATCCTGAGTACGGTCA
TACAGCTGGTGTAGATGCAACTACTGGTCCACTTGGACAAGGTATTGCAACTGCTGTAGGTATGGCAATGGCAGAAAGAC
ATTTAGCTGCTAAATATAACCGTGATGCGTATAATATAGTAGATCATTATACATACGCTATTTGTGGTGATGGAGATTTA
ATGGAAGGCGTTTCTGCTGAAGCATCTTCATTAGCTGCTCATTTACAATTAGGTCGTCTTGTTGTGCTTTATGATTCAAA
CGATATTTCATTAGATGGCGATTTAAATCGTTCATTCTCTGAAAGTGTAGAAGATCGTTACAAAGCATACGGATGGCAAG
TAATCCGTGTTGAGGATGGAAACGATATTGAAGCTATCGCGAAAGCAATCGAAGAAGCGAAAGCTGACGAAAAACGCCCA
ACGCTAATTGAAGTAAGAACGACAATTGGTTTCGGTTCTCCAAACAAATCAGGAAAATCAGCTTCACATGGTTCTCCACT
TGGTGTAGAAGAAACAAAGTTAACGAAAGAAGCATACGCTTGGACTGCTGAACAAGACTTCCATGTAGCAGAAGAAGTAT
ATGAAAACTTCCGTAAAACAGTACAAGATGTTGGTGAAACTGCACAAGCTGAGTGGAATACTATGCTAGGTGAATATGCA
CAAGCATATCCAGAATTAGCAAACGAACTGCAAGCAGCAATGAACGGTCTTCTTCCAGAAGGTTGGGAGCAAAACTTACC
AACTTATGAATTAGGATCAAAAGCAGCAACTCGTAATTCTTCAGGTGCTGTAATTAATGCAATTGCAGAGTCTGTACCAT
CATTCTTCGGTGGATCTGCTGACCTTGCTGGTTCTAACAAAACATACATGAATAACGAAAAAGACTTTACAAGAGATGAT
TACAGCGGTAAAAACATTTGGTACGGTGTACGTGAGTTCGCAATGGGTGCAGCAATGAACGGTATTGCACTACATGGTGG
TTTAAAAACTTACGGTGGTACGTTCTTCGTATTCTCTGACTACTTACGCCCAGCAATTCGTCTTGCAGCATTAATGCAAT
TGCCGGTAACGTATGTATTCACACACGACAGTATCGCTGTTGGTGAAGATGGTCCAACACATGAACCAATCGAGCAATTA
GCAGCGCTACGTGCAATGCCAAATGTATCTGTTATTCGTCCAGCTGACGGTAACGAATCTGTTGCAGCTTGGAGACTAGC
TCTAGAATCTACAAACAAACCAACTGCTTTAGTATTAACTCGTCAAGATCTTCCAACATTAGAAGGTGCAAAAGACGATA
CGTATGAAAAAGTAGCAAAAGGTGCGTATGTAGTTTCTGCAAGCAAGAAAGAAACAGCTGATGTAATCTTACTTGCAACT
GGATCTGAAGTAAGTCTAGCTGTTGAAGCTCAAAAAGCATTAGCAGTAGACGGCGTTGATGCATCTGTTGTCAGCATGCC
ATCTATGGATCGCTTTGAAGCTCAAACAGCTGAGTACAAAGAATCTGTATTACCAAAAGCAGTAACAAAACGTTTCGCAA
TCGAAATGGGTGCTACATTCGGATGGCACCGTTACGTAGGTCTTGAAGGAGATGTGTTAGGTATCGATACATTCGGTGCT
TCTGCTCCTGGTGAGAAGATTATGGAAGAGTATGGATTTACTGTAGAGAACGTTGTTCGTAAAGTAAAAGAAATGCTTTA
A

Protein sequence :
MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLS
GYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNIVDHYTYAICGDGDL
MEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIAKAIEEAKADEKRP
TLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGETAQAEWNTMLGEYA
QAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDD
YSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL
AALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVSASKKETADVILLAT
GSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGA
SAPGEKIMEEYGFTVENVVRKVKEML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-155 50
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-155 50