Gene Information

Name : guaA (GBAA_0268)
Accession : YP_016877.2
Strain : Bacillus anthracis Ames Ancestor
Genome accession: NC_007530
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 260908 - 262446 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAGAAGCAACACGATACAATTATCGTTTTAGATTTTGGAAGTCAATACAATCAGTTAATAGCACGTCGAATTCGTGA
GTTCGGTGTATACAGTGAGCTTCATCCACATACAATTACTGCGGAAGAAATTAAAGCAATGAATCCAAAAGGGATTATCT
TCTCTGGTGGACCAAATAGTGTATACGGTGAAGGCGCATTACATTGTGATGAAAAAATCTTTGACCTAGGATTACCGATC
TTCGGTATTTGTTACGGTATGCAACTTATGACGCAACAATTCGGTGGTACAGTAGAGCGTGCAAACCACCGTGAGTACGG
AAAAGCTGTTCTGAAAGTAGAGAACGAGTCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGATGAGTCATG
GCGACTTAGTAACTGGTTTACCTGAAGGATTCGTAGTAGACGCGACAAGTGAGTCTTGCCCAATTGCTGGTATGAGCAAT
GAAGCGAAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGTAACGATTTAATTAAAAACTT
CGTATTCGGCGTATGTGGCTGTTCTGAAGGATGGAACATGGAGAACTTTATTGAAGTAGAACTAGAGAAAATCCGTGAAA
CTGTTGGAGACAAAAAAGTACTATGTGCGCTTAGCGGCGGTGTAGATTCTTCTGTTGTAGCAGTATTAATTCATAAAGCA
ATCGGCGATCAGTTAACATGTATTTTCGTTGACCATGGTTTACTTCGTAAAGGCGAAGCAGAAGGTGTTATGAAAACATT
TAGCGAAGGCTTCCACATGAACGTTATTAAAGTGGATGCAAAAGAACGCTTCATGAACAAGTTAAAAGGTGTAGAAGATC
CAGAACAAAAACGTAAAATTATCGGTAACGAATTCATTTACGTATTTGATGATGAAGCTTCTAAATTAGAAGGAATGGAC
TTCTTAGCACAAGGTACACTGTACACAGATATCGTTGAAAGTGGTACAGCAACTGCACAAACAATTAAATCTCACCATAA
CGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAACACGTTATTTAAAGATGAAGTACGTGTAT
TAGGATCTGAACTAGGAATTCCTGATGAGATCGTATGGCGTCAACCATTCCCAGGTCCTGGTCTTGGTATTCGTGTACTA
GGTGAAATCACGGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCGATTTTACGTGAAGAAATTATTAAAGCAGGCTT
AGACCGCGAAATCTGGCAATACTTCACTGCGCTTCCTGGTATGCGTAGCGTAGGTGTTATGGGTGACGAGCGTACTTACG
ATTACACAGTGGGTATCCGTGCAGTAACATCTATCGACGGTATGACAGCTGACTGGGCACGTATCCCTTGGGACGTATTA
GAGAAAATCTCTGTACGTATCGTAAACGAAGTGAAACACGTTAACCGTATCGTGTATGATGTAACGAGTAAGCCACCAGC
AACTATTGAGTGGGAATAG

Protein sequence :
MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLGLPI
FGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSN
EAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKA
IGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLEGMD
FLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVL
GEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVL
EKISVRIVNEVKHVNRIVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-140 55