Gene Information

Name : dhbE (GBAA_2370)
Accession : YP_019014.1
Strain : Bacillus anthracis Ames Ancestor
Genome accession: NC_007530
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2204067 - 2205683 bp
Length : 1617 bp
Strand : +
Note : 'similar to GB:L20320, GB:X79193, GB:X77303, SP:P50613, PID:1486357, PID:2125816, PID:348243, PID:468789, PID:485909, GB:L20320, GB:X79193, GB:X77303, SP:P50613, PID:1486357, PID:2125816, PID:348243, PID:468789, and PID:485909; identified by sequence simi

DNA sequence :
ATGTTAACAGGTTATACAAAATGGCCAAAAGAATTTGCCGATCGCTATCGAGAGGAAGGGTGTTGGCTTGGGGAAACATT
TGGCGGAGTGTTAAGAGAGCGTGCTGAAAAATATGGAGATCAAATTGCGGTTGTAAGTGGTAATACGTATATAACATATA
GTGAGCTTGATAAAAAAGTAGATCGCTTAGCGTCAGGTTTACTGAATTTAGGAATAAAGCCAGAAGATCGAGTTGTAATC
CAACTACCTAATGTTATCGAGTTTTTTGAAATGTGTTTTGCACTATTTCGAATTGGAGCACTTCCTGTTTTTGCATTACC
TTCACATCGCAGTAGTGAAATTAGTTATTTTTGTGAGTTTGGTGAGGCAAGTGCGTACGTTATTTCAGATAAGGCTCTTG
GTTTTGATTATCGAAAACTAGCAAGAGAAGTGAAAGAGAAAGTACCAACTTTACAACATGTAATTGTAGTGGGAGAAAAA
GAAGAGTTTGTGAACATAAGTGATTTATATATAGATCCCGTTCTATTGCCAGAAGTTCAGCCAAGTGATGTTGCGTTTCT
CCAATTATCAGGAGGGACAACAGGACTTTCTAAATTAATTCCTAGAACGCATGATGACTATATTTATAGTTTACGTGTTA
GCGCTGAAATTTGTAATTTAAGTGCAGAGAGCGTCTATATGGCAGTTCTTCCAGTAGCACATAATTACCCAATGAGTTCT
CCTGGAACATTTGGAACCTTTTATGCGGGTGGAAAAGTTGTGCTGGCAACTGGGGGTAGTCCGGATGAGGCATTTGCACT
TATCGAAAAAGAAAAAGTTACGATTACTGCTCTCGTACCGCCATTAGCAATGATATGGCTTGACGCTGCATCTTCACGTA
ATAACGATTTATCAAGCCTAGAAGTGATTCAAGTAGGTGGTGCAAAATTTAGTGCTGAAGTTGCAAAACGGATACGTCCT
ACATTTGGATGTACATTACAGCAAGTGTTCGGTATGGCAGAAGGATTAGTGAACTATACAAGATTAGATGATCCGGAAGA
AATTATAATTCATACACAAGGTAGACCAATGTCTGCACTTGATGAAGTACGAGTTGTTGACGAATATGATAACGATGTAA
AACCTGGTGAAGTAGGTAGTTTATTAACACGGGGTCCATATACAATTCGTGGTTATTATAAAGCAGAAGAGCATAATGCA
CGATCATTTACAAATGATGGATTTTATCGCACAGGAGATCTTGTAAAAGTAAATGAACAAGGTTACATCATTGTAGAAGG
AAGAGATAAAGATCAAATTAATCGTGGTGGTGAGAAAGTCGCTGCGGAAGAAGTTGAAAATCATCTATTAGCACATGATG
CAGTACATGATGTAGCGATTGTATCTATGCCTGACGATTATTTAGGAGAGCGTACTTGTGCATTTGTAATAGCTCGCGGA
CAAGCTCCGGCAGTAAGTGAATTAAAAAGGTTCTTAAGAGAACGCGGTATAGCAGCTTATAAGATTCCAGATCGAATTGA
ATTTATTGAATCATTCCCGCAAACAGGTGTTGGAAAGGTAAGCAAAAAAGAATTACGTAAAGTCATTGCGGAAAAACTTG
TTACGGTAAAAAGATAA

Protein sequence :
MLTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVSGNTYITYSELDKKVDRLASGLLNLGIKPEDRVVI
QLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISYFCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEK
EEFVNISDLYIDPVLLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVAHNYPMSS
PGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSRNNDLSSLEVIQVGGAKFSAEVAKRIRP
TFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQGRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNA
RSFTNDGFYRTGDLVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTCAFVIARG
QAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKELRKVIAEKLVTVKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-126 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-125 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-126 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-125 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-125 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-125 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-125 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-125 50
ybtE CAA21394.1 - Virulence HPI Protein 1e-125 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_019014.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-140 52
dhbE YP_019014.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-116 48
dhbE YP_019014.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-116 45