Gene Information

Name : Tcr_2141 (Tcr_2141)
Accession : YP_392403.1
Strain : Thiomicrospira crunogena XCL-2
Genome accession: NC_007520
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2362280 - 2363026 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAACTTACGTCTTTATTCCTGCTCGTTACGGTTCTTCGAGACTGCCTGGCAAGCCGCTTAAATTAATTAATGGCAA
ACCGATGATTCAACATGTTTTTGAGCGCATTTCAAAAGCAACGGGCATTGAAGCCGTCTACGTCGCGACCGATGACGACC
GCATTAAAGAAGTGGTTGAAAAATTCGGTGGAAACGTTGTCATGACCCCACCTGAAGCGGAATCGGGTACAGACCGAATT
GCTCAAGCCGCGCAGGCGTTGGATTTAAAAGAGGACGACCTGATTGTCAATGTTCAAGGCGACCAGCCGCTGGTCAATCA
AGGTTCGATTGAAGCGGTTATCGCCCCTTTCAAAGCAGCTGATTACGATGGTTCGTTTGAAATGAGCACCCTTTCTTTTA
AAATCGTTAATGAAGCGGAAATTACCAGTCCGAAAGACGTTAAGCTGGTCACCGATGTCAACGGATTTGCACTCTACTTC
TCACGGGCAACCATTCCTCATGGTCGCGACTACTGGGATCATGATTCTTATAAGCATTTAGGGGTTTACGCTTATACCAA
GCGTTTTGTGGATCTTTTTAATACCTTACCAATGGGTCACTTGGAAGACATCGAAAAACTTGAACAGCTACGAGCACTCG
AATATGGGCATAAAATCAAGGTCGTCGAAAGTGAATGGGATTCCCCTGAAGTGGATTTGCCGGGCGATATCGAAATGATG
GAAGCACTGTTAAACGCAGGCCATTAA

Protein sequence :
MKTYVFIPARYGSSRLPGKPLKLINGKPMIQHVFERISKATGIEAVYVATDDDRIKEVVEKFGGNVVMTPPEAESGTDRI
AQAAQALDLKEDDLIVNVQGDQPLVNQGSIEAVIAPFKAADYDGSFEMSTLSFKIVNEAEITSPKDVKLVTDVNGFALYF
SRATIPHGRDYWDHDSYKHLGVYAYTKRFVDLFNTLPMGHLEDIEKLEQLRALEYGHKIKVVESEWDSPEVDLPGDIEMM
EALLNAGH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-39 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-39 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-39 41