Gene Information

Name : smpB (Tcr_1409)
Accession : YP_391678.1
Strain : Thiomicrospira crunogena XCL-2
Genome accession: NC_007520
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1520152 - 1520628 bp
Length : 477 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAGAAAAAAAAGCAAAACAATCCAAACAGTATCGCTCAAAATAAAAAAGCGCGTTTCGACTATTTTATTGAAGA
AACCTTTGAAGCGGGCTTAGCGCTTGAAGGCTGGGAAGTCAAAAGTCTCCGCCAAGGAAAAGTGCAAATTAATGAAAGCT
ATATTTTGCTTAAAAACAACGAAGCCTGGCTTTTTGGCGCGCTGATTACCCCACTTATCACAGCTTCAACCCACTCCAAT
CACGACCCGTTAAGGCTTAGAAAACTCCTGATGCACCGAAGAGAAATCGATCGTTTAATGGGGTTGGTCGACCAAAAAGG
CTTTACGGTGGTTCCATTAGGCCTTCATTGGAGCAAAGGAAAAGTCAAAATTTCCATTGGCCTCGCAAAAGGTAAAAAAC
TTCATGACAAACGCGCGACTCAAAAAGAGCGTGATTGGAACCGTGACAAACAACGTATCATGAAGTACCACGCATAA

Protein sequence :
MAKKKKQNNPNSIAQNKKARFDYFIEETFEAGLALEGWEVKSLRQGKVQINESYILLKNNEAWLFGALITPLITASTHSN
HDPLRLRKLLMHRREIDRLMGLVDQKGFTVVPLGLHWSKGKVKISIGLAKGKKLHDKRATQKERDWNRDKQRIMKYHA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 7e-39 57
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-24 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-21 44