Gene Information

Name : Dde_1859 (Dde_1859)
Accession : YP_388351.1
Strain : Desulfovibrio alaskensis G20
Genome accession: NC_007519
Putative virulence/resistance : Virulence
Product : Restriction endonuclease, type I, EcoRI, R subunit/Type III
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 1907890 - 1910883 bp
Length : 2994 bp
Strand : -
Note : KEGG: geb:GM18_2921 hypothetical protein; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal

DNA sequence :
ATGAAACCGACTGACACCAGCGAAAAGGGCCTGGAATCGATTATCGTCGCCTCCCTTGTGGAGGATGCCGGATACGTTCA
GGGTGATCCGCAGGACTACGACCGGGAACACGCTGTCGACCTGGCCAAACTACTGCAATTCCTCGCCGCCACCCAACCAG
ATACCTATGAGGCTCTCGGCATCGACGAGGAAGGCCCCAAGCGCACCCAGTTTCTGCACCGCCTGCAGGGCGAAATCGCC
AAACGCGGCGTGGTAGACGTGCTGCGCGGCGGCATCAAGCACGGCCCGGCCCATGTGGACCTTTTCTACGGCACGCCGAC
GCCGGGCAACGTGAAGGCGGCCGAACGGTTCGCGGCCAACATCTTCAGCGTCACCCGCCAGCTTCGCTACAGCCGCAACG
AGACCGCGCTCTCCCTCGACATGGCCGTGTTCATCAACGGCCTGCCCATCGCCACCTTCGAACTCAAGAACAAACTCACC
AAGCAGACGGTGCTCGATGCCGTGCAACAGTACCAGCGCGACCGCGACCCGAAGGAGCTGCTGTTCCAGTTCGGCCGCTG
CGCCGTGCATTTTGCCGTGGACGATCACGAGGTGCGTTTCTGTACCCACCTCAAGGGCAAGGGCTCGTGGTTTCTGCCCT
TCGACAAGGGCTACAACGATGGCGCGGGCAATCCGCCCAACCCGGCCGGGCTCGCCACCGACTACCTTTGGAAGGAGACC
CTCTCCAAGGAGGGTCTGACCGACATCCTGGAAAACTACGCTCAGGTGGTGGAGGAAAAAGACGAGAAGACCGGCAAAAA
GAGGTACAAGCAGATATTCCCTCGCTACCACCAGTTGAAGGTGGTGCGCATGCTGCTGGCCAATGCCGCTGAGAGCGGCA
TCGGCAGGCGCTACCTGATCCAGCACTCGGCGGGCAGCGGCAAAAGTAACTCCATCGCCTGGCTGGCGCACCAGCTTGTG
GGGCTGGAACACGAGAGCAAGGCGTTGTTCGACTCGGTGATCGTGGTCACCGACCGACGGGTGCTCGACAAACAGATCCG
CGACACCATCAAGCAGTTCGCCCAGGTCTCCGCCACAGTCGGCCATGCCGAACACTCCGGCGACCTACGCAAATTCCTCA
AGGCCGGGAAGAAAATCATCATCACCACCGTGCAGAAGTTTCCGTTCATCCTCGACGAGATCGGTGACGAACACCGCAAG
AGCAAATTCGCCATCATCATCGACGAGGCCCATTCCAGCCAGGGCGGCAAAACCACCGCTGCCATGAACCGCGTGCTGGA
GGAGACCGCGCCCTATGGCGGCTCTGATGACGAGGAGGAAGAGACGGTCGAGGACAAGATCAACAAGATCATGGAAGGCC
GGAAGATGGTGACCAACGCCAGCTACTTCGCCTTCACCGCGACCCCCAAGAACAAGACCCTGGAGATCTTCGGCGAGCCG
GACCCGCAGCCGGACGGCACCGTGAAGCATCACCCGTTCCACAGCTACACCATGAAGCAGGCCATCCAGGAGGGTTTCAT
CCTCGATGTGCTGAAGAACTACACCCCGGTGGAGAGCTATTACCGCCTGGCCAAGACCGTGGAGGACGACCCGCTCTTCG
ACGCCAACAAGGCCCAGAAAAAGCTGCGCCGCTATGTGGAGTCCCACGAGCACGCCATCCGCGAGAAGGCGGAGATTATG
GTGGACCATTTCCACGCCCAGGTGATCGGCCACCGCAAGATCGGCGGCCATGCCCGGGCCATGGTCATCACCAACGGTAT
CGAGCGGGCCATCCAGTATTTCCACGCCTTCAGGGACTATCTCAAAGAGCGCAAAAGCCCTTACGCACCCATCGTGGCTT
TTTCCGGGGAGCACGAGTACGGCGGCAAGAAAGTCACCGAGTCGACGCTGAACGGCTTTCCCAGCAGCCAGATCCCGGAC
AAGGTACAACAGGACCCGTACCGCTTCCTGATCGTCGCCGACAAGTTCCAGACCGGCTACGACGAACCGCTGCTGCACAC
CATGTACGTGGACAAGGCGCTCTCCGGCATCAAGGCGGTGCAGACCCTCTCGCGGCTCAATCGCGCCCATCCGCAGAAGC
ACGACACTTTTGTGCTCGATTTCTACAACGACTCGGAGACCATCCAGAGGTCGTTCGAGCCCTATTACCGCACCACCATC
CTCAGTGACGAGACCGACCCCAACAAGCTCCATGATCTGAAGTCGGATCTGGACGGCTACCAGGTCTATTCGCAGGTACA
AATCGACGACCTGGTGGGGCTCTATCTGAACGGCGCGGACCGCGACAAGCTCGACCCGATCCTGGATGCCTGCGTGGCCA
CCTACAACGCCGATCTCGATGAGGACGGCCAGGTGGACTTCAAAGGCAAAGCCAAGGCCTTCGTCCGCACCTACGGCTTT
CTGTCCTCGATCCTGGCGTACTCGAATGCCGACTGGGAAAAGCTGTCGATCTTCCTGAACTTCCTGATCCCGAAACTCCC
CGCGCCCAAGGAAGAGGACCTGTCCCGGGGCATCCTGGAGGCCATCGACATGGACAGCTACCGTGTCGAGGTGAAAACCA
GCCTGAAGATCGGCCTTCCGGATCAGGATGCCGAAATCGGACCGGTGCCGACCACCGGTAGTGGCCGCAAACCGGAACCG
GAGCTGGACCAACTGAGCAACATCATCAAGGCGTTCAACGACCAGTTCGGCAACATCGATTGGAAGGACGGCGACAAGAT
CCGCAAGGTCATTGCCGAGGAGATCCCGGCCAAGGTCGCGGCGGACGCGGCCTACCAGAACGCCATGAAGAACAACGACA
AGAAGACCGCCCGGATCGAGCACGACGCCGCGCTGCAACGCGTCATGATCGACCTCTTGTCCGACCACACCGAGCTGTTC
AAGCAGTTCAGCGACAACCCGTCGTTCAAGAAATGGCTTGGCGACACCATCTTCGGCGTGACCTATCAGCAACAGGCCGA
ACAATCCGCAACGGGGGCGAGCCATGGACGTTAA

Protein sequence :
MKPTDTSEKGLESIIVASLVEDAGYVQGDPQDYDREHAVDLAKLLQFLAATQPDTYEALGIDEEGPKRTQFLHRLQGEIA
KRGVVDVLRGGIKHGPAHVDLFYGTPTPGNVKAAERFAANIFSVTRQLRYSRNETALSLDMAVFINGLPIATFELKNKLT
KQTVLDAVQQYQRDRDPKELLFQFGRCAVHFAVDDHEVRFCTHLKGKGSWFLPFDKGYNDGAGNPPNPAGLATDYLWKET
LSKEGLTDILENYAQVVEEKDEKTGKKRYKQIFPRYHQLKVVRMLLANAAESGIGRRYLIQHSAGSGKSNSIAWLAHQLV
GLEHESKALFDSVIVVTDRRVLDKQIRDTIKQFAQVSATVGHAEHSGDLRKFLKAGKKIIITTVQKFPFILDEIGDEHRK
SKFAIIIDEAHSSQGGKTTAAMNRVLEETAPYGGSDDEEEETVEDKINKIMEGRKMVTNASYFAFTATPKNKTLEIFGEP
DPQPDGTVKHHPFHSYTMKQAIQEGFILDVLKNYTPVESYYRLAKTVEDDPLFDANKAQKKLRRYVESHEHAIREKAEIM
VDHFHAQVIGHRKIGGHARAMVITNGIERAIQYFHAFRDYLKERKSPYAPIVAFSGEHEYGGKKVTESTLNGFPSSQIPD
KVQQDPYRFLIVADKFQTGYDEPLLHTMYVDKALSGIKAVQTLSRLNRAHPQKHDTFVLDFYNDSETIQRSFEPYYRTTI
LSDETDPNKLHDLKSDLDGYQVYSQVQIDDLVGLYLNGADRDKLDPILDACVATYNADLDEDGQVDFKGKAKAFVRTYGF
LSSILAYSNADWEKLSIFLNFLIPKLPAPKEEDLSRGILEAIDMDSYRVEVKTSLKIGLPDQDAEIGPVPTTGSGRKPEP
ELDQLSNIIKAFNDQFGNIDWKDGDKIRKVIAEEIPAKVAADAAYQNAMKNNDKKTARIEHDAALQRVMIDLLSDHTELF
KQFSDNPSFKKWLGDTIFGVTYQQQAEQSATGASHGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 2e-178 42
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 1e-178 42
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 1e-178 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dde_1859 YP_388351.1 Restriction endonuclease, type I, EcoRI, R subunit/Type III VFG1098 Protein 5e-179 42