Gene Information

Name : guaA (Syncc9605_0046)
Accession : YP_380380.1
Strain : Synechococcus sp. CC9605
Genome accession: NC_007516
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 43316 - 44902 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCCAGCCCTCGTCCGACACTCAGCGTCAGCCGGCCATCGTCATTCTTGATTTCGGCTCCCAGTATTCGGAACTGAT
TGCCCGACGGGTGCGCGAGACCGAGGTGTTTTCGGTGGTGCTCGGTTACAGCACTTCGGCGGAGGAGCTGCGACGCATGG
CTCCGAAGGGAATCATCCTCAGCGGTGGCCCCAGCTCCGTGTATGCCGAACATGCGCCGCTCTGCGATCCCGGCATCTGG
GATCTGGGCATTCCCGTGCTGGGGGTTTGCTACGGGATGCAGTTGATGGTGCAGCAGCTTGGTGGCGTTGTGGAAGCCGC
CACGGGCAAGGCCGAATACGGCAAGGCGCCCCTGGAAGTGGATGACCCAACGGACCTGCTCACCAACGTCGACAACGGCT
CGACGATGTGGATGAGCCATGGCGACTCGGTGAAGGCCCTCCCCGAGGGGTTTGTGCGCTTGGCCCACACCGCCAACACC
CCGGAAGCGGCGGTGGCGCACCTGCAACGCAAGCTCTACGGCGTGCAGTTTCACCCCGAGGTGGTGCATTCCACCTGCGG
CATGGCCCTGATCCGCAATTTCGTGTATCACGTTTGCGGTTGTGACCCGGATTGGACCACCGCGGCATTCATCGATGAAG
CCGTTGCCCTGGTTCGGGAGCAGGTGGGCGACAAACGCGTCCTGCTGGCCCTCTCCGGCGGTGTGGATTCATCCACTCTC
GCCTTTCTGCTGAAAAAGGCGATCGGTGATCAGCTCACCTGCATGTTCATCGATCAGGGCTTCATGCGGAAGGGCGAGCC
TGAGTTCCTGATGGACTTCTTCGATCGGAAGTTCAACATCCATGTGGAGTACATCAATGCGCGCCAGCGGTTCATCGGCA
AGCTGGAGGGCATCACCGATCCGGAGGAGAAGCGCAAGATCATCGGCACCGAGTTCATCAGGGTGTTCGAAGAGGAGAGC
AAGCGCCTCGGACCCTTTGATTACCTGGCCCAGGGAACGCTTTACCCCGATGTGATCGAAAGTGCCGGCACCAACGTTGA
TCCGAAGACGGGTGAACGGGTTGCCGTGAAGATCAAGAGCCACCACAACGTGGGCGGCCTGCCCAAGGATCTTCAGTTCA
AGCTGGTGGAGCCCCTTCGCAAGCTGTTCAAGGACGAAGTGCGCAAGGTGGGCCGCAGCCTCGGTCTGCCCGAGGAAATT
GTGCGCCGCCATCCCTTCCCGGGGCCTGGTCTAGCCATACGGATCCTGGGTGAAGTCACCGACGAAAAGCTGGATTGTCT
GCGTGATGCCGACTTGATCGTTCGCCAGGAAATCAAGGAGGCAGGGCTGTATCACGACATCTGGCAGGCCTTTGCAGTGC
TGCTGCCGGTGCGTTCCGTTGGGGTGATGGGCGACAAGCGCACCTATGCTTGGCCGATCGTGCTGCGCTGTGTGTCCAGT
GAGGACGGGATGACCGCCGATTGGTCCCGCCTCCCCTACGACCTGATGGAGACCATCTCCAATCGGATCGTGAATGAGGT
GAAGGGGGTGAACCGGGTGGTGCTCGACATCACCAGCAAGCCTCCCGGCACGATTGAGTGGGAATAG

Protein sequence :
MSQPSSDTQRQPAIVILDFGSQYSELIARRVRETEVFSVVLGYSTSAEELRRMAPKGIILSGGPSSVYAEHAPLCDPGIW
DLGIPVLGVCYGMQLMVQQLGGVVEAATGKAEYGKAPLEVDDPTDLLTNVDNGSTMWMSHGDSVKALPEGFVRLAHTANT
PEAAVAHLQRKLYGVQFHPEVVHSTCGMALIRNFVYHVCGCDPDWTTAAFIDEAVALVREQVGDKRVLLALSGGVDSSTL
AFLLKKAIGDQLTCMFIDQGFMRKGEPEFLMDFFDRKFNIHVEYINARQRFIGKLEGITDPEEKRKIIGTEFIRVFEEES
KRLGPFDYLAQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRKVGRSLGLPEEI
VRRHPFPGPGLAIRILGEVTDEKLDCLRDADLIVRQEIKEAGLYHDIWQAFAVLLPVRSVGVMGDKRTYAWPIVLRCVSS
EDGMTADWSRLPYDLMETISNRIVNEVKGVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-140 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-140 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-140 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-134 53