Gene Information

Name : lysS (Syncc9605_0110)
Accession : YP_380441.1
Strain : Synechococcus sp. CC9605
Genome accession: NC_007516
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 108346 - 109854 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGTCTGAGCTGCGCGACACCCGTCTGGAAAAGGCGAGGACATTGGAGGAGCTGGGGCAGGGCCCCTATGCCCTCACCTT
TAGCCCCAGCCACCGCATGGCTGAGCTACAGGTGACCCATGCCGATCTCCCCAAGGGGGAAGAGCGGGACGTCAGCGTTT
CCGTGGCGGGGCGGGTGATGACCCGCCGGGTGATGGGAAAGTTGGCCTTTTTCACCCTGGCCGATGAGACGGGTTCCATC
CAGCTGTTCCTGGAGAAGGCGGGGCTGGAGGCCCAGCAGGAGGGCTGGTTCAAACAGATCACCTCGTTGGTGGACAGTGG
CGACTGGCTTGGGGTGAGCGGCACCCTGCGTCGCACTGACCGAGGTGAACTGTCGGTAAAGGTGAGCGACTGGCGCATGC
TCACCAAGGCGCTGCAGCCCCTTCCCGACAAGTGGCATGGTCTGGCCGACGTGGAGAAGCGCTACCGCCAGCGTTACCTG
GATCTGGTGGTGTCTCCCGACAGCCGGGAGACGTTCCGGCGCCGGGCCCGCCTGGTGAGCGGCATTCGCCGCTGGCTTGA
TCAACGGGATTTTCTCGAGATCGAGACCCCCGTGTTGCAGAGCGAACCCGGTGGCGCCGACGCGCGACCGTTCGAGACCC
ATCACAACGCTCTCGATCTGCCCCTCACCCTCCGGATTGCCACCGAGTTACACCTCAAGCGCCTGGTGGTGGGCGGCTTT
GAGCGGGTTTATGAACTGGGCCGGATCTTCCGCAATGAAGGGGTTAGCACCCGCCATAACCCCGAGTTCACTTCGGTGGA
GATCTATCAGGCCTACAGCGACTACGTCGGGATGATGGAGCTCACCGAGCAGATGGTCAGCGCGGTGTGTGAAGAGGTCT
GCGGCACGACCACCATCACCTACCAGGGCACCGAGATCGATCTGGCACCGCCGTGGCGGCGCGCCACCATGCACGAGCTC
GTGCAAGACGCGACGGGGCTTGATTTCAATGGCTTCAGCAGTCGGGAGGAGGCGGCCGCGGCGATGACCGCCAAGGGTCT
GCATGCACCTGAACTGGCCGACTCGGTGGGCCGTCTGCTCAATGAAGCCTTTGAGCAAGCGGTGGAGACGACCCTGATTC
AGCCCACCTTCGTCACCGATTACCCGGTAGAGATTTCGCCCCTGGCCCGGCCCCATCGCAGCAAGCCAGGCCTGGTGGAG
CGCTTTGAGTTGTTCATCGTCGGCCGCGAGCACGCCAATGCCTTCAGTGAGCTCACCGATCCTGTGGATCAACGGCAGCG
CCTCGAGGCCCAGCAGGCGCGCAAGGCGGCGGGCGACCTGGAAGCGCAGGGGTTGGACGAGGATTTCGTAATGGCCCTGG
AGGTGGGCATGCCCCCCACGGGAGGTCTGGGGATCGGCATCGACCGGTTGGTGATGCTGCTCACCGACTGCCCTTCGATT
CGGGATGTGATCGCCTTCCCGCTGTTGCGGCCGGAGTCCCGCAAGGGAGAACCACCCTCAGTGGAATAA

Protein sequence :
MSELRDTRLEKARTLEELGQGPYALTFSPSHRMAELQVTHADLPKGEERDVSVSVAGRVMTRRVMGKLAFFTLADETGSI
QLFLEKAGLEAQQEGWFKQITSLVDSGDWLGVSGTLRRTDRGELSVKVSDWRMLTKALQPLPDKWHGLADVEKRYRQRYL
DLVVSPDSRETFRRRARLVSGIRRWLDQRDFLEIETPVLQSEPGGADARPFETHHNALDLPLTLRIATELHLKRLVVGGF
ERVYELGRIFRNEGVSTRHNPEFTSVEIYQAYSDYVGMMELTEQMVSAVCEEVCGTTTITYQGTEIDLAPPWRRATMHEL
VQDATGLDFNGFSSREEAAAAMTAKGLHAPELADSVGRLLNEAFEQAVETTLIQPTFVTDYPVEISPLARPHRSKPGLVE
RFELFIVGREHANAFSELTDPVDQRQRLEAQQARKAAGDLEAQGLDEDFVMALEVGMPPTGGLGIGIDRLVMLLTDCPSI
RDVIAFPLLRPESRKGEPPSVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 9e-107 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 8e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_380441.1 lysyl-tRNA synthetase VFG1668 Protein 5e-107 48