Gene Information

Name : tpx (Cag_0624)
Accession : YP_378940.1
Strain : Chlorobium chlorochromatii CaD3
Genome accession: NC_007514
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 898616 - 899122 bp
Length : 507 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCACAAATTAATTTAAAGGGAAATCCCATTGAAACCGTTGGAACGCTACCTGTAAAAGGTACCGAAGCGCCATTTTT
TTGTTTGGTGAAAACTGATTTATCGGAAGCTGGTCCCGCTGATTTTGCCAGCAACAAGTTGGTATTAAACATTTTTCCAA
GTCTCGATACTCCTGTTTGTGCCGCTTCAGTGCGCCGTTTTAATCAAGAAGCTGCATCCTATCCCAACACGGTAGTGCTC
TGCATTTCAGCCGATTTACCTTTTGCCCACAATCGTTTTTGTGAAGTTGAAGGGTTAAAAAATGTTGTTCCCCTTTCAGT
GTTTCGTTCACCTGAATTTGGACAGCAATATGGTGTTACTATTACAACTGGTCCATTAAAAGGATTGCTTTCTCGTGCAT
TAGTTGTTGTTGATGCCGATGGTGTGGTTCGTTACACCGAGCAGGTGCCTGAAATTGTGCAGGAACCCGATTATGATGCA
GCATTAAAAGTGGTTGCTTCGCTCTAA

Protein sequence : 
MAQINLKGNPIETVGTLPVKGTEAPFFCLVKTDLSEAGPADFASNKLVLNIFPSLDTPVCAASVRRFNQEAASYPNTVVL
CISADLPFAHNRFCEVEGLKNVVPLSVFRSPEFGQQYGVTITTGPLKGLLSRALVVVDADGVVRYTEQVPEIVQEPDYDA
ALKVVASL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-30 43
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-30 43
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-30 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-30 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_378940.1 thiol peroxidase VFG0087 Protein 8e-31 43