Gene Information

Name : guaA (Cag_0589)
Accession : YP_378905.1
Strain : Chlorobium chlorochromatii CaD3
Genome accession: NC_007514
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 691317 - 692852 bp
Length : 1536 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAATCAGTTTTAGTGCTTGATTTTGGTTCACAATACACCCAGCTTATTGCTCGCCGCATTCGCGAACTCAATATTTA
CTCCGAAATTCTTCCCTACAACACTCCAGCCGATACCATTCGCACCCATCAGCCAAAAGCCATTATTCTTTCAGGCGGAC
CAAACAGCGTTTATGACCAAACCGCTTTTATGCCCGATCCCGCTATCTTTTCGCTTGGCATTCCCGTGCTTGGCATTTGT
TATGGCTTGCAAGCAATTGCCAAACACTTTGGCGGCGTAGTTGCAAGTTCCAACAAGCATGAATTTGGACGCTCAAAAAT
TTTGGTGGAACAGCAAGGCGATAATCCCCTCTTTCAAAACATCCCTAACTCTGATGTGTGGATGAGCCATGGCGACAAAG
TGATGCAGCTCCCCGAAGGCTTTCGAGCTACCGCCAGCAGCGACAACTCCGAAATTTGCGCCTTTGAAAGCACAGGAGTT
AATAGCCCCGCTCATATTTACGGCTTACAATTCCACCCCGAAGTTCAGCACACCCTTTACGGCAAAGAGATGCTTGGCAA
CTTTTTGCTCAACATTGCAGCCATTACGCCCGACTGGTCCAGCAAAAGCTTTATAGAGCACCAAATTGAGGAGATTCGCC
GCAAAGCAGGCAACAACACCGTTATTTGCGGCATTAGCGGCGGCGTGGACTCTACGGTTGCCGCCGTGTTAGTTAGCAAA
GCTATTGGCAAGCAACTCCACTGCGTTTTTGTAGATAATGGCTTGTTGCGCAAAAATGAAGCCGAAAAAGTGATGCACTT
CCTCAAACCACTTGGCTTACACATCACCTTAGCCGACTCCTCCGACCTCTTTTTAAAACGCTTAAAAGGCGTTGCCTCAC
CCGAAAAAAAGCGCAAAATTATTGGACGCACCTTTATTCAAGTCTTTGAAGAGCAAATCCATCACGAAAAATTTCTTGTG
CAGGGCACGCTTTACCCCGATGTAATTGAAAGTATAAGCGTTAAAGGACCATCGGAAACCATTAAATCGCACCACAACGT
TGGCGGACTACCCAAACGCATGAAGCTCAAGCTCATTGAGCCACTACGCGAACTTTTTAAGGATGAAGTACGGGCGGTTG
GCAGAGAACTTGGTATTCCTGAAGATATTCTCATGCGCCACCCCTTCCCTGGTCCAGGACTTGCCGTCCGAGTGCTTGGC
TCACTTACGCATGAACGGTTAGAAATACTGCGCGAAGCTGATGAAATTTACATTGAAGAATTACAAGCAAGCGGACTTTA
CAGTAAAGTTTGGCAAGCCTTTGCCGTGCTGCTCCCCGTGCAATCGGTAGGCGTTATGGGCGATAAACGCACCTACGAAA
ACGTGCTTGCCTTGCGTGCTGTGGAATCAAGCGACGGTATGACGGCAGATTGGGCTCCCCTACCGCACGACTTTCTTGCT
CGCGTTTCAAACCGCATTATCAATGAAGTTCGAGGTATTAACCGCGTAGCTTACGACATTTCATCGAAGCCTCCAGCAAC
GATTGAGTGGGAATAG

Protein sequence :
MQSVLVLDFGSQYTQLIARRIRELNIYSEILPYNTPADTIRTHQPKAIILSGGPNSVYDQTAFMPDPAIFSLGIPVLGIC
YGLQAIAKHFGGVVASSNKHEFGRSKILVEQQGDNPLFQNIPNSDVWMSHGDKVMQLPEGFRATASSDNSEICAFESTGV
NSPAHIYGLQFHPEVQHTLYGKEMLGNFLLNIAAITPDWSSKSFIEHQIEEIRRKAGNNTVICGISGGVDSTVAAVLVSK
AIGKQLHCVFVDNGLLRKNEAEKVMHFLKPLGLHITLADSSDLFLKRLKGVASPEKKRKIIGRTFIQVFEEQIHHEKFLV
QGTLYPDVIESISVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIPEDILMRHPFPGPGLAVRVLG
SLTHERLEILREADEIYIEELQASGLYSKVWQAFAVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAPLPHDFLA
RVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-134 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-134 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-134 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-125 51